Sentences with word «pigmentary»

We have to be absolutely sure that the Goldens we think are clear of pigmentary uveitis truly are clear as we start screening genes.

Symptoms of Pigmentary Uveitis (PU) include, but aren't limited to, squinting, increased tearing or discharge, redness, photophobia (light sensitivity) and cloudiness of the eye or eyes.

Clinical features shared by all 5 subgroups of canine ischemic dermatopathy given above include alopecia with crusting and post-inflammatory, mottled pigmentary change.

Corneal changes called pigmentary keratitis (brown to black pigment deposition on the surface of the eye causing a «marble» like appearance) were apparent, which commonly occurs in dogs afflicted by Keratoconjunctivitis Sicca («dry eye»).

We will discuss the unique clinical presentation that differentiates Golden Retriever Pigmentary Uveitis from other causes of canine uveitis.

Dr. Theos» research seeks to better understand changes within the cells of the eye that die as a prelude to the development of a type of inherited glaucoma known as pigmentary glaucoma.

Dr. Rachel Keller immediately diagnosed Piper with pigmentary uveitis in both eyes, a condition common to golden retrievers, in which an inflammation develops and may block the normal drainage of fluids from the eye, resulting in higher than normal pressure within the eye, or glaucoma.

Dr. Pandya, the only full - time pigmentary disorders specialist in Texas, has spent more than a decade treating vitiligo patients in the Pigmentation Disorders Clinic at UT Southwestern.

The cause of pigmentary keratopathy is multifactorial.

Annual eye examinations are recommended for the lifetime of the dog due to late onset of eye disorders such as pigmentary uveitis.

It remains now to investigate whether this novel secretory route may be exploited by other specialized cells, or targeted in pigmentary disorders or skin cancers like melanoma.

They examined skin color variation in 2000 African individuals from different geographic locations and ethnic groups; the range, from light - skinned San hunter - gatherer populations in southern Africa to dark - skinned pastoralist populations in eastern Africa, far exceeds pigmentary diversity anywhere else on the planet (see the figure).

He said while AMD is not necessarily hard to diagnose, the early forms, which show pigmentary changes and few small drusen, can be very subtle and require a very detailed fundus examination.

There has been a great deal of discussion regarding pigmentary uveitis since it was first described as a disease of Golden Retrievers (Sapienza et al, 2000).

Pigmentary aberrations give rise to poikilodermatous change with either hyper or hypopigmentation.

Canine Anterior Uveitis Canine Lens Luxation Chronic Superficial Keratitis (Pannus) Corneal Dystrophy and Corneal Degeneration Entropion Follicular Conjunctivitis in dogs Keratoconjunctivitis Sicca (Dry Eye) Parotid Duct Transposition Pigmentary Kera and GC Uveitis Progressive Retinal Atrophy SARDS Uveal Cyst Uveodermatologic Syndrome

If the eyelids can not protect the eyes, blinding pigmentary changes will form where the eyes become irritated.

This disease also goes by the names Golden Retriever Uveitis, and also Pigmentary Uveitis; the most recently embraced term, however, is GRPU.

Golden Retriever Pigmentary Uveitis (GRPU) was first described and published in 1996 within the American College of Veterinary Ophthalmologists Genetic Committee report of «Ocular Disorders Presumed to be Inherited in Purebred Dogs».

(2008) Early transport deficits and distal axonopathy in the DBA / 2J mouse model of pigmentary glaucoma (Investigative Ophthalmology & Visual Science, 49: ARVO E-Abstract 3664).

If this dog has previously provided a blood sample at a National Specialty or directly to the CHIC DNA Repository, and has since been diagnosed with pigmentary uveitis:

Pigmentary keratopathy occurs in dogs with shallow orbits and incomplete blinking, especially the Pug.

Pigmentary keratitis: an inflammatory condition of the cornea characterized by abnormal pigmentation.

pigmentary disorders (melasma), infection (warts), hair loss, and even neoplasms (basal cell carcinoma).

(2008) Age - dependent changes in morphologically identified glial cell populations in the optic nerve of the DBA / 2J mouse model of pigmentary glaucoma (Investigative Ophthalmology & Visual Science, 49: ARVO E-Abstract 3693).

Many dogs have pigmentary changes as they grow older.

«This is a very important discovery that will guide future research efforts to explore the interactions of these pigmentary genes with other genetic and environmental risk factors in cancers not linked to sun exposure, such as eye melanoma.

However, it will take more research to determine whether other forms of the disease, like normal tension, acute, pigmentary, and trauma - related glaucoma, could also benefit from these encouraging findings.

Project: GPNMB Deficiency and Associated Cytotoxicity in Pigment Dispersion Syndrome, a Precursor of Pigmentary Glaucoma

More specifically, we investigate the interactions between physical (mechanics, reaction - diffusion, photonics) and biological (cell signalling, proliferation, differentiation) mechanisms that generate and constrain the variety and complexity of skin appendages (scales, hairs, spines), skin colours (pigmentary and structural), and skin colour patterns in tetrapods (four - limbed vertebrates).

(2009) Structural Persistence of the Retinal Ganglion Cell Projection in the DBA / 2J Mouse Model of Pigmentary Glaucoma (Investigative Ophthalmology & Visual Science, 50: ARVO E-Abstract 2777).

Fossil specimens of adult macrolepidopterans often exhibit light - and dark - toned areas on their wings [14] and can retain ultrastructural details of their scales [15]; preservation of pigmentary or structural colors has not been reported.

I have a pigmentary abnormality on my forehead, nose, and on my cheeks.

Pigmentary Uveitis (PU) or Pigmentary Cystic Glaucoma (PCG) is a bilateral inherited disease of Golden Retrievers.

Pigmentary keratopathy / keratitis in the dog is due to pigment migration onto the cornea and is a frequent cause of blindness in the Pug, Shih Tzu and Pekingese.

More severe cases of GVIID and GIID must be differentiated from other inflammatory diseases where extensive alopecia and pigmentary changes are seen.

Blood samples from families (parents and offspring if possible) in which both parents of a litter have been diagnosed with pigmentary uveitis.

The best way to be sure the individual is not affected with pigmentary uveitis is to have histopathologic (microscopic) examination performed of the eyes.

Pigmentary Uveitis (PU) is a disease of the eye, it seems to be found at around age 8, but there are many cases found much earlier (2) and some much later.