Sentences with phrase «pigmentation gene»

The same study found that in Shetland Sheepdogs a mutation of the pigmentation gene known as Silver (or Silv) is probably responsible for the merle pattern.

Previous studies of a skin pigmentation gene called MC1R had led many geneticists to think that dark skin colour — which is thought to protect against UV damage — is a fixed and consistent trait in all people of African descent.

He argues that some pigmentation genes have such a powerful effect that they override the combined contributions of many weaker genes — a phenomenon that would render the new study's simple gene addition inaccurate.

«Increased eye cancer risk linked to pigmentation genes that dictate eye color: New research identifies genetic mechanisms behind rare form of melanoma are also associated with genetic risk for skin melanoma.»

Two pigmentation genes in particular are often associated with deafness in dogs: the merle gene (seen in the collie, Shetland Sheepdog, Dappled Dachshund, Harlequin Great Dane, American Foxhound, Old English Sheepdog, and Norwegian Dunkerhound among others) and the piebald gene (Bull Terrier, Samoyed, Greyhound, Great Pyrenees, Sealyham Terrier, Beagle, Bulldog, Dalmatian, English Setter).

Not exact matches

Doctors believe Catherine has a recessive gene for the pigmentation, because baby Jonah is not albino, just white.

Another reason why a baby might have Heterochromia iridium or Heterochromia iridis is Waardenburg syndrome in which a gene mutation occurs, causing changes in the pigmentation levels of the hair, iris and skin.

More than a hundred sites in the genome showed strong evidence of recent selection, including genes that affect muscle tissue, hair, hearing, immune - system function, skin pigmentation, sense of smell, and the body's response to heat stress.

«Our work helps us to understand what causes human diversity in appearance by showing how genes involved in pigmentation subtly adapted to external environments and even social interactions during our evolution.

We identify previously uncharacterized genes and variants associated with skin pigmentation in ethnically diverse Africans.

Joint lead author Professor Manfred Kayser from Erasmus MC said: «Besides substantially increasing our understanding of human pigmentation genetics in general, finding these new hair colour genes is also important for further increasing the accuracy of hair colour prediction from DNA traces in future forensic applications, which can help to find unknown perpetrators of crime.»

Variation in pigmentation among human populations may reflect local adaptation to regional light environments, because dark skin is more photoprotective, whereas pale skin aids the production of vitamin D. Although genes associated with skin pigmentation have been identified in European populations, little is known about the genetic basis of skin pigmentation in Africans.

The researchers also looked at the gene expression of skin cells from people with psoriasis and found decreased expression of the genes involved in pigmentation signaling, correlated with increased amounts of IL - 17 and TNF.

«There are also other disease genes that lead to the pigmentation disorder,» says Betz.

In its normal form, the gene produces a hormone that inhibits eating and also influences hair pigmentation.

Several different variants are all uniquely associated with pigmentation near these genes, and variants in these genes have been associated with pigmentation in animals.

Only about 10 percent of this variation can be attributed to genes known to affect pigmentation.

By working closely with the KhoeSan, a group of populations indigenous to southern Africa, the researchers have found that the genetics of skin pigmentation become progressively complex as populations reside closer to the equator, with an increasing number of genes — known and unknown — involved, each making a smaller overall contribution.

In addition, the researchers found some unexpected insights into particular genes associated with pigmentation.

The two groups, they found, had different versions of a crucial gene, one that coded for a protein involved in pigmentation.

«If you can find a gene for blond hair that exists in Melanesia and nowhere else,» Myles says, «then there's no reason why those sorts of genes don't exist all over world in underrepresented populations, and affect not only hair pigmentation, but also disease - related traits.»

The authors report that genes encoding heme synthetic enzymes (that generate porphyrin intermediates) are expressed in pigment cells, and the first three enzymes in the heme synthetic pathway are also required for proper pigmentation.

Compared with the ancestral lineage, the East African cichlid genomes possess: an excess of gene duplications; alterations in regulatory, non-protein-coding elements in the genome; accelerated evolution of protein - coding elements, especially in genes for pigmentation; and other distinct features that affect gene expression, such as insertions of transposable elements and regulation by novel microRNAs.

We also show that genes involved in skeletal morphology have changed more than expected on the Neandertal evolutionary lineage whereas genes involved in pigmentation and behavior have changed more on the modern human lineage.

Mutations in the genes SLC24A5 and SLC45A2 are largely responsible for European pigmentation, showing only single amino acid differences between Europeans and West Africans.

But rather than changes in doublesex itself, these studies revealed changes in downstream targets of dsx, via changes to specific DNA sequences to which DSX protein binds in the cis - regulatory regions of the bric - a-brac and desatF genes and affecting sex differences in abdominal pigmentation and pheromone production.

Nearly every one of the young flies carried the gene, for yellow pigmentation.

Among the changes Gantz inserted in his flies with CRISPR was a gene for yellow pigmentation.

From the European Commission Research & Innovation website: «Scientists identify gene behind blood orange pigmentation», Researchers in China, Italy and the United Kingdom have discovered what gene is responsible for blood orange pigmentation, and how it is controlled.

Approximately 15 genes have been directly associated with skin pigmentation variation in humans, leading to its characterization as a relatively simple trait.

In addition, the data reveal that this was a more genetically diverse population than the central and western European hunter - gatherers living during the same epoch and that they also show pattern of adaptation to high latitude environments, including high frequencies of low pigmentation variants as well as a gene region associated with physical performance, which shows strong continuity into modern - day northern Europeans.

In their study, researchers gave the name Ruby to the gene they identified as playing a key role in the pigmentation of the blood orange.

All these things like; skin pigmentation, eye color, certain diseases are the result of our parent's genes which present in our body.

The Catahoula leopard dog is very well known for its Merle gene and pigmentation but seems to always be an ignored breed by dog enthusiasts for some unknown reason

This is actually a natural trait of the breed as opposed to Weimaraners, for example, who have blue eyes due to a gene that inhibits pigmentation.

The merle gene affects the production of melanin, a molecule responsible for pigmentation, sight and hearing.

Siberian Huskies have a specific gene that causes a loss of pigmentation in the irises but not the coat, which is why Huskies can have dark coats and blue eyes.

Usually, though, blue coloring is due to a gene that dilutes the pigmentation of the dog's coat and eyes.

Dogs who have the merle gene, such as Australian shepherds and Weimaraners, may have light blue eyes as a result of a random loss of pigmentation caused by the gene.

In addition to affecting coat colors, genes also control pigmentation of the total body including the eyes and skin as well as coat color.

Dogs with green eyes and the Merle gene also have less pigmentation in the iris of the eye, which can affect their eyesight.

It's because of the merle gene, which decreases pigmentation.

In this case the deafness is neither dominant nor recessive, but is linked to a dominant gene that disrupts pigmentation and as a secondary effect produces deaf dogs.

Instead, he receives his blue coloring from a recessive gene that forms a clump of color pigmentation around the hair shaft and leaves the tip of the hair without color.

The researchers have shown that Synechococcus cyanobacteria — which use light to capture carbon dioxide from the air and produce energy for the marine food chain — contain specific genes which alters their pigmentation depending on the type of light in which they float.