BUT, we now know from the PROTECT2 study that in Dobermanns with early - stage DCM (i.e. heart enlargement on ultrasound but no symptoms of CHF), treatment with
pimobendan delays the onset of CHF by an average of 9 months.
Not exact matches
The EPIC Study showed that administration of
pimobendan resulted in a 15 ‑ month
delay in time to primary endpoint compared with dogs receiving placebo.
To determine whether chronic oral administration of
pimobendan in dogs with evidence of increased heart size secondary to preclinical myxomatous mitral valve disease (MMVD) can
delay the onset of clinical signs of congestive heart failure (CHF).1
This is because the recently published EPIC1 study showed that early treatment with
pimobendan in MVD Stage B2 dogs will
delay the development of symptoms of congestive heart failure (CHF) by an average of 15 months.
The QUEST Study established
pimobendan as the new standard of treatment for dogs with congestive heart failure (CHF) caused by MMVD as it extended survival time.2 The veterinary community also sought to answer this question: Can
pimobendan also
delay the onset of clinical signs of CHF?
The EPIC Study showed that administration of
pimobendan resulted in a 15 ‑ month
delay in onset of clinical signs of CHF, cardiac ‑ related death, or euthanasia compared with dogs receiving placebo.
This groundbreaking study sought to answer a key question: Can
pimobendan — with proven efficacy in treating dogs with congestive heart failure (CHF) caused by myxomatous mitral valve disease (MMVD)-- also
delay the onset of CHF caused by MMVD?
Recent results from the EPIC Study, however, show that
pimobendan, when administered to dogs in stage B2 — before clinical signs of heart failure appear — succeeded in
delaying the onset of CHF.
The EPIC (Evaluation of
Pimobendan In dogs with Cardiomegaly) Study1 analysed whether long - term administration of pimobendan to dogs with stage B2 myxomatous mitral valve disease (MMVD) and echocardiographic and radiographic evidence of cardiac enlargement will delay onset of clinical signs of congestive heart failure (CHF), cardiac - related death, or euthanasia (composite primary
Pimobendan In dogs with Cardiomegaly) Study1 analysed whether long - term administration of
pimobendan to dogs with stage B2 myxomatous mitral valve disease (MMVD) and echocardiographic and radiographic evidence of cardiac enlargement will delay onset of clinical signs of congestive heart failure (CHF), cardiac - related death, or euthanasia (composite primary
pimobendan to dogs with stage B2 myxomatous mitral valve disease (MMVD) and echocardiographic and radiographic evidence of cardiac enlargement will
delay onset of clinical signs of congestive heart failure (CHF), cardiac - related death, or euthanasia (composite primary endpoint).