Sentences with phrase «pivotal studies of»

NYU Langone was the first hospital in the tri-state area to use MarginProbe ®, and our physician - researchers were part of a pivotal study of over 600 women that led to its approval by the FDA.

Not exact matches

For ALKS 3831, we recently completed enrollment of the ENLIGHTEN - 2 pivotal study, with topline data expected in the fourth quarter of 2018.

Greenland's coastal glaciers and ice caps have passed a pivotal tipping point — a new study concludes that they've melted so much that they're now past the point of no return, and it's unlikely in current conditions that they'll be able to regrow the ice they've lost.

In August of 2007, for example, Health Minister Tony Clement referred to one of the RCMP studies when he told a pivotal meeting of the Canadian Medical Association, «There has been more research done, and some of it has been questioning of the research that has already taken place and questioning of the methodology of those associated with Insite.»

Management continues to believe that the refined manufacturing process utilized in pivotal studies will ranslate into improved normalization of total hemoglobin levels across all genotypes.

Incyte frankly conceded that its pivotal failure raised doubts about its entire effort, which includes a host of combination studies with checkpoint leaders like Merck and AstraZeneca.

In this dipolar case study, Gregory enunciated a pivotal maxim that may be taken to be a major principle of his pastoral care: «certain faults beget others.

The uniqueness of the child - father attachment relationship: Fathers» sensitive and challenging play as a pivotal variable in a 16 - year long study.

The uniqueness of the child - father attachment relationship: fathers» sensitive and challenging play as a pivotal variable in a 16 - year longitudinal study

The study comes at a pivotal moment for Europe, with many still reeling from an intensely bad tempered loan negotiation process which saw Greece nearly thrown out of the eurozone.

While further study of larger patient groups with longer follow - up times is needed for this cohort of prostate cancer patients, this study is pivotal in providing evidence for change in practice.»

«We are encouraging people to come in and to get to the place where they are ready to do their pivotal studies and to submit a premarket approval application,» says Stayce Beck, chief of the FDA's Diabetes Diagnostic Devices Branch.

The study, which is being conducted under the Environmental Protection Agency's Superfund program, is the first time the EPA has undertaken its own water analysis in response to complaints of contamination in drilling areas, and it could be pivotal in the national debate over the role of natural gas in America's energy policy.

Three studies presented at the American Epilepsy Society's 69th Annual Meeting in Philadelphia highlight emerging efficacy and safety data of Epidiolex, a pharmaceutical liquid formulation of cannabidiol, which is currently undergoing U.S. Food and Drug Administration (FDA) authorized Phase 3 pivotal clinical trials in the United States and across the globe by GW Pharmaceuticals.

These studies suggest that children, particularly teens, should play a pivotal role in the design and development of mobile apps designed to keep them safe online.

The study found that the insulin - like growth factor 1 (IGF - 1) hormone, known for its pivotal role in tissue growth, is also capable of increasing the lithium sensitivity of blood cells in bipolar disorder patients in whom lithium was originally ineffective.

'' «Imitate your child» is just one example of an ART intervention strategy that is targeted to address one of 12 pivotal behaviors in our study,» Baranek said.

The idea that the balance between excitatory and inhibitory inputs depends on astrocyte signals gains strong support with this new study and suggests a pivotal role for astrocytes in the development of neurological disorders involving impaired inhibitory synapse transmission.

Animal Days (1979) traced Morris's life from childhood through the pivotal event of his life, the 1967 publication of The Naked Ape, the first widely read study of Homo sapiens from the viewpoint of a zoologist.

This pivotal trial is the largest study conducted of renal artery denervation as a treatment for resistant hypertension and the most rigorously designed, including blinding and a sham treatment in the control arm.

At the end of the study, 84 percent of parents who received instruction in pivotal response training were using the therapy correctly.

«The ability of WaterFALL to simulate water flows within individual, small segments of rivers and streams was pivotal in enabling the study team to develop statistically significant correlations between changes in streamflow and biological diversity and richness at each of the locations where biological inventories had been prepared by the North Carolina Department of Environmental Quality,» said Michele Eddy, lead developer of the WaterFALL ® model and member of RTI's study team.

Indeed, the findings of this study have important implications for today's concern about the loss in diversity of bees, a pivotal species for agriculture and biodiversity.

The notion that CD4 + T cells might be the pivotal mediators of corneal graft rejection arose from studies demonstrating the close correlation between delayed - type hypersensitivity (DTH), a classical CD4 + T cell - mediated immune process, and corneal graft rejection in rodents (10, 11).

The study, published in Human Molecular Genetics, has shown that the majority of genes associated with Nephrotic Syndrome (NS) in humans are also pivotal in Drosophila renal function, validating transgenic flies as accurate pre-clinical models.

While studying a mutant strain of yeast, Horwich said he found himself in a research dilemma that became a pivotal point in his career.

Table 1: Selection, Design & Construction of HSV - based Oncolytic Viruses Table 2: Selection, Design & Construction of Adenovirus - based Oncolytic Viruses Table 3: Selection, Design & Construction of Vaccinia Virus - based Oncolytic Viruses Table 4: Selection, Design & Construction of Vesicular Stomatitis Virus - based Oncolytic Viruses Table 5: Selection, Design & Construction of Newcastle Disease Virus - based Oncolytic Viruses Table 6: Selection, Design & Construction of Various Virus - based Oncolytic Viruses Table 7: Current Company - Sponsored Clinical Trials of T - Vec Table 8: Clinical Trials of ColoAd1 Table 9: Clinical Trials with JX - 594 Table 10: Clinical Trials with GL - ONC1 Table 11: Clinical Trials of CAVATAK (CVA21) Table 12: Clinical Trials with MV - NIS Table 13: Overview of Oncolytic Viruses by Development Phase & Virus Family Table 14: Profile of Approved and Marketed Oncolytic Viruses Table 15: Pivotal Study Design of Oncolytic Viruses in Late Stage Development Based on Previous Clinical Results Table 16: Approved Indications of Immune Checkpoint Inhibitors Table 17: Active Clinical Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 18: Planned Clinical Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 19: Active or Planned Clinical Studies of Oncolytic Viruses in Combination with Other Anti-Cancer Therapeutics Table 20: Pattern of Transgenes in Oncolytic Viruses in Relation to Development Phase Tables 21a and 21b: Indications and Frquency and Way of Administration of Oncolytic Viruses in Active and / or Positive Completed Clinical Studies Table 22: Small and Medium Pharma & Biotech as Partner for Regional Co-Development of Oncolytic Viruses Table 23: Immuno - Oncology Portfolio of Major Pharma & Biotech with Interest in Oncolytic Viruses Table 24: Interests of Major Pharma & Biotech in Oncolytic Viruses Table 25: First Generation Oncology Virus Companies and their Sources of Technology Table 26: Second Generation Oncology Virus Companies and their Sources of Technology Table 27: Third Generation Oncology Virus Companies and their Sources of Technology Table 28: Fourth Generation Oncology Virus Companies and their Sources of Technology Table 29: Grants, Credits & Donations Table 30: Financing by Venture Capital, Private Equity and Other Private Placements Table 31: Collaboration & Licensing Agreements Table 32: Companies Listed on Stock Exchange & Offerings Table 33: Mergers & Acquisitions

Phase 1 clinical trials give patients at University of Michigan access to pivotal early - stage studies, connecting families to novel treatment therapies to patients before they are widely available.

This was feasible by the advent of Atacama Large Millimeter Array (ALMA), located on a mountaintop plateau in Chile, which works in tandem to detect electromagnetic waves at a wavelength range in the millimeter (pivotal for studying molecular gas) and a sensitivity level that is just starting to be explored by astronomers today.

Fueled by a recent resurgence in public financing and compelling clinical data for indications as diverse as acute macular degeneration and pancreatic cancer, a growing number of cell therapies are driving toward pivotal clinical studies and commercialization.

Commencement of the pivotal portion of either study will trigger a $ 20 million milestone payment to PTC from Roche.

Through studying human individuals with a genetic mutation that increases the activity of the glucokinase enzyme, which is responsible for a pivotal step in the pathway, they demonstrated the migratory patterns of Tregs into tissues.

The pivotal study published in the New England Journal of Medicine in 1997 showed that the DASH diet substantially reduced blood pressure.

(The primary author of that pivotal study,...

But before slapping on a global health message, we can not forget one of the most a pivotal components of analyzing research — the study population.

It takes him a while to get to the pivotal event that turns «Out of the Furnace» from a lived - in character study into a violent tale of vengeance.

In examining the causes of charter school closures in the United States, former National Charter Schools Institute CEO Brian Carpenter reported in 2008 that low enrollment was pivotal in the demise of almost three - fourths of the 100 cases he studied.

Always «at the right place at the right time,» Nieto found herself a pivotal figure in many movements in multicultural education, from bilingual education and bilingual teacher education to the introduction of ethnic studies in higher education, and has continued her activism throughout her career.

In addition to changes related to program structure, such as those raised by the recent high - profile Teachers College study, the question of content is pivotal; principals receive limited training in the use of data, research, technology, the hiring or termination of personnel, or using data to evaluate personnel in a systematic way.

Always «at the right place at the right time,» Nieto found herself a pivotal figure in many movements in multicultural education, from bilingual education and bilingual teacher education to the introduction of ethnic studies in higher education, and has continued...

A pivotal piece of the equation: Get to know your students well, and develop strong relationships, says Roberto Gonzales, who has studied the experiences of undocumented young people for years.

In a study for the University of Phoenix Research Institute, the Institute for the Future explains that we are at a pivotal point in time where several disruptive shifts are in progress.

Through his work with the HR 1103 Joint Study Committee and the Alliance of Agency Heads Math / Science Task Force, Mr. Henson played a pivotal role in advancing the preparation and compensation of Georgia mathematics and science teachers.

Reports such as the Pew Foundation study, The Digital Disconnect, have underscored the pivotal role of school leadership in ensuring that technological resources are effectively employed.

This is not a story heavy on plot, but is instead, a fascinating and deep study of the heart and head of one woman at one pivotal moment in her life.

When you are requesting custom case studies from scratch by highly qualified writers, it is pivotal for you to depict every one of the points of interest of the planned exposition to be composed.

Some puppies may have higher levels of maternal antibodies than those evaluated in our pivotal efficacy study.

A randomized, blinded, placebo - controlled pivotal field study to evaluate the effectiveness and safety of robenacoxib (tablets) when administered at a dose of 2 mg / kg once daily for 3 days for the control of postoperative pain and inflammation associated with soft - tissue surgery in dogs.

Florham Park, N.J. — August 13, 2013 — Results of a new pivotal study show that APOQUEL ® (oclacitinib tablet) provides effective and safe control of pruritus associated with allergic dermatitis in dogs with a rapid onset of efficacy within 24 hours and without the commonly reported side effects of steroids.

In a pivotal efficacy study, dogs receiving the Vanguard CIV H3N2 / H3N8 vaccine were protected from disease after CIV H3N2 challenge.2, 3,4 Vaccination also appeared to help decrease the number of days after challenge that dogs shed CIV H3N2 virus — from an average of 4.9 days in the placebo - vaccinated controls to an average of 1.3 days in Vanguard CIV H3N2 / H3N8 vaccinates.2, 5,6