Sentences with phrase «placebo arms»

However, to have the statistical power to confirm trends even in these populations would probably take at least 100 people in both the treatment and placebo arms of the trial.

Two recent, late - stage clinical trials were stopped because nusinersen, developed by Ionis of Carlsbad, California, and now licensed to Biogen of Cambridge, Massachusetts, was so effective in restoring motor function in children and babies that it was deemed unethical to deny the drug to children in the placebo arms of the trials.

The study was designed to accumulate 1,612 MACE at which level the study was robustly designed to have 90 % power to detect a 15 % relative risk reduction in MACE between the Vascepa and placebo arms of the study.

Bone loss was higher in men compared to women in the placebo arm, and the protection against bone loss was higher in men than in women in the treatment arm.

Treatment with zoledronic acid was associated with an eight percent increase in lumbar spine bone marrow density at 12 weeks relative to the placebo arm, with an 11 percent increase at 24 and 48 weeks.

Participants in the placebo arm had a compensatory increase in bone formation, which was an expected result, but bone formation was flat in the treatment arm.

«Such a study would be feasible and ethically justifiable if one excluded certain high - risk groups so that antibiotic treatment would not be withheld from them in the placebo arm.

In absolute terms, the overall survival rate at five years was 11 % higher in the ipilimumab arm (65 %) than in the placebo arm (54 %).

The board recommended that the study abandon its placebo arm and now offer treatment to all uninfected participants.

Widely hailed as a «breakthrough» in HIV prevention by public health officials, the studies — one of which dropped its placebo arm today because of the convincing effects of the intervention — add powerful new tools to derail transmission of the virus in the population that accounts for most of the 34 million infections in the world.

The placebo arm received fulvestrant plus placebo.

The foundation's petition calls for a complete halt of the trial of healthy short children, and of the placebo arm of the Turner's syndrome trial.

«But human trials of sitagliptin have been limited to date because they have lacked important tools like a placebo arm and allocation concealment (in which researchers do not know what the next treatment allocation will be, further preventing selection bias in testing),» said Loomba.

Nearly 40 % of patients in the active group, vs. 6.3 % in the placebo arm, achieved PASI 100 (completely clear skin) at week 24.

100 % (n = 23) and 87 % (n = 20) achieved titers consistent with protection at day 43 as measured by HAI titers and MN titers, respectively, compared to 0 % in the placebo arm.

Yesterday, away from the conference, it was reported that the placebo arm of a European trial studying the antiretroviral Truvada used as PrEP will be stopped early and volunteers will be offered the antiretroviral because of its observed effectiveness at preventing HIV infection.

Median duration of response had not been reached in the nivolumab plus ipilimumab arm; it was 31.1 months and 18.2 months for the nivolumab plus placebo arm and ipilimumab - alone arm, respectively.

The two groups were evenly matched with regard to rates of response to induction therapy (44 % complete or partial response in the pemetrexed arm vs. 42 % placebo arm).

Second, this study included a placebo arm.

Throughout the trial, a placebo arm has been used, to help distinguish drug effects from the effects of being in the trial, such as the injection procedure.

All patients underwent induction therapy with four cycles of pemetrexed and cisplatin, and then the pemetrexed arm received pemetrexed continuation maintenance therapy until disease progression while the placebo arm received best supportive care.

In the placebo arm, GS010 will be administered as a single intravitreal injection to the first affected eye, while the fellow eye will receive a placebo injection.

In fact, more patients in the placebo arm stopped taking treatment than those who received the fish - oil supplements (17.9 % in n - 3 fatty acid group vs 19.4 % in the placebo group).

Fruits and vegetables are associated with lower lung cancer risk only in the placebo arm of the beta - carotene and retinol efficacy trial (CARET).

Not exact matches

In the study, 20 participants were randomized to receive a placebo pill or 50,000, 100,000, or 200,000 IU of vitamin D one hour after a small UV lamp «sunburn» on their inner arm.

The three - armed trial evaluated the efficacy of chiropractic spinal manipulative therapy (CSMT) in the treatment of migraine versus placebo (sham chiropractic) and control (usual drug treatment).

Among subjects who had prediabetes at the beginning of the study (arm 2), blood sugar levels reverted to normal in nearly 70 percent of those receiving liraglutide versus 32 percent of people in the placebo group, according to the abstract.

For the second arm, among 2,285 individuals with prediabetes, liraglutide went to 1,528 of them and placebo to 757.

The patients were randomized to treatment and control arms at a 2:1 ratio (with 345 treated and 172 receiving placebo).

According to the trial's crossover design, patients with refractory chronic cough of at least eight weeks» duration were randomly assigned initially to either AF - 219 or placebo treatment twice daily for two weeks, followed by a washout period, and further followed by crossover to the alternative treatment arm (AF - 219 or placebo) for an additional two weeks.

Half the men (the experimental group) applied a gel with testosterone to their shoulders, abdomen or upper arms each day for a year, and the other half (the control group) used a gel containing a placebo.

All remaining placebo patients crossed over to the guselkumab arm at week 24.

Even more impressive, 17 % of patients died in the placebo group versus 9 % in the CoQ10 arm.

No group [veggie, meat eater placebo or creatine arm] did better in word recall at the end of study than at baseline!

Perhaps the barrage of tests should be repeated with black coffee, black tea, green tea, M&M s and placebo control arms.

In the primary analysis, we will combine results across all eligible intervention arms (parent training programmes, i.e. courses or written materials), and compare them with the combined results across all eligible control arms (another intervention (s) or placebo), making single, pairwise comparisons.