Sentences with phrase «placebo arms of»

However, to have the statistical power to confirm trends even in these populations would probably take at least 100 people in both the treatment and placebo arms of the trial.

Two recent, late - stage clinical trials were stopped because nusinersen, developed by Ionis of Carlsbad, California, and now licensed to Biogen of Cambridge, Massachusetts, was so effective in restoring motor function in children and babies that it was deemed unethical to deny the drug to children in the placebo arms of the trials.

The study was designed to accumulate 1,612 MACE at which level the study was robustly designed to have 90 % power to detect a 15 % relative risk reduction in MACE between the Vascepa and placebo arms of the study.

The foundation's petition calls for a complete halt of the trial of healthy short children, and of the placebo arm of the Turner's syndrome trial.

Yesterday, away from the conference, it was reported that the placebo arm of a European trial studying the antiretroviral Truvada used as PrEP will be stopped early and volunteers will be offered the antiretroviral because of its observed effectiveness at preventing HIV infection.

Fruits and vegetables are associated with lower lung cancer risk only in the placebo arm of the beta - carotene and retinol efficacy trial (CARET).

Not exact matches

In the study, 20 participants were randomized to receive a placebo pill or 50,000, 100,000, or 200,000 IU of vitamin D one hour after a small UV lamp «sunburn» on their inner arm.

The three - armed trial evaluated the efficacy of chiropractic spinal manipulative therapy (CSMT) in the treatment of migraine versus placebo (sham chiropractic) and control (usual drug treatment).

Among subjects who had prediabetes at the beginning of the study (arm 2), blood sugar levels reverted to normal in nearly 70 percent of those receiving liraglutide versus 32 percent of people in the placebo group, according to the abstract.

For the second arm, among 2,285 individuals with prediabetes, liraglutide went to 1,528 of them and placebo to 757.

Widely hailed as a «breakthrough» in HIV prevention by public health officials, the studies — one of which dropped its placebo arm today because of the convincing effects of the intervention — add powerful new tools to derail transmission of the virus in the population that accounts for most of the 34 million infections in the world.

According to the trial's crossover design, patients with refractory chronic cough of at least eight weeks» duration were randomly assigned initially to either AF - 219 or placebo treatment twice daily for two weeks, followed by a washout period, and further followed by crossover to the alternative treatment arm (AF - 219 or placebo) for an additional two weeks.

«But human trials of sitagliptin have been limited to date because they have lacked important tools like a placebo arm and allocation concealment (in which researchers do not know what the next treatment allocation will be, further preventing selection bias in testing),» said Loomba.

Nearly 40 % of patients in the active group, vs. 6.3 % in the placebo arm, achieved PASI 100 (completely clear skin) at week 24.

Median duration of response had not been reached in the nivolumab plus ipilimumab arm; it was 31.1 months and 18.2 months for the nivolumab plus placebo arm and ipilimumab - alone arm, respectively.

The two groups were evenly matched with regard to rates of response to induction therapy (44 % complete or partial response in the pemetrexed arm vs. 42 % placebo arm).

Throughout the trial, a placebo arm has been used, to help distinguish drug effects from the effects of being in the trial, such as the injection procedure.

All patients underwent induction therapy with four cycles of pemetrexed and cisplatin, and then the pemetrexed arm received pemetrexed continuation maintenance therapy until disease progression while the placebo arm received best supportive care.

Even more impressive, 17 % of patients died in the placebo group versus 9 % in the CoQ10 arm.

No group [veggie, meat eater placebo or creatine arm] did better in word recall at the end of study than at baseline!

Perhaps the barrage of tests should be repeated with black coffee, black tea, green tea, M&M s and placebo control arms.