Sentences with phrase «placebo controlled clinical»

Summit raised the additional capital through an issue of 8,333,333 new ordinary shares (before expenses) whereby the proceeds will be used to: accelerate preparatory activities for a placebo controlled clinical trial of the utrophin modulator ezutromid in patients with -LSB-...]

The logistical difficulties and considerable expense of long term placebo controlled clinical trials of dietary components mean it is unlikely that high level evidence linked to cardiovascular disease outcome will be obtained in the near future.

Furthermore, Asensia ®'s formula has been used safely for more than 12 years with over a million bottles sold and studied in a double - blind placebo controlled clinical trial.

Of note today: non-exclusive breastfeeding increases the risk of HIV transmission via the alteration of gut microbiome / T - cell activation; Fasting altered the gut microbiome in beneficial ways but only in mice previously fed a high fat diet; An investigation into new species of the honey and bumblebee gut commensal genus Gilliamella; Catfish development shapes gut microbial community structure independent of diet; A metagenomic analysis of the skin microbiome of the frog, Craugastor fitzingeri; The microbiome is altered during the bioremediation of herbicide contaminated soil; The impact of urban density on the soil microbiome; A randomized placebo controlled clinical trial of a microbiota based drug for the prevention of Clostridium difficile Infection; and the virome of the Cuatro Ciénegas Basin of Mexico

«We have now found a potential mechanism, and at this point in our research, we need to test human participants in a blinded, placebo controlled clinical study — the same technique we used to study the behavioral effects of acupuncture in rats,» says Eshkevari, a nurse anesthetist and licensed acupuncturist.

Not exact matches

He contributes to other large - scale clinical trials including SAVE (evaluating whether treatment of obstructive sleep apnoea with continuous positive airways pressure can reduce the incidence of serious CV events in patients with established CVD), and CREDENCE, a randomised, double - blind, placebo - controlled trial assessing whether canagliflozin can slow the progression of diabetic nephropathy in patients with type 2 diabetes.

Dr Jaeger and Dr Wilson recruited 24 healthy, college - aged, resistance - trained participants with an average age of 21 to participate in their double - blind, placebo - controlled clinical trial.

While the gold standard of clinical research is the double - blind, placebo - controlled, randomized clinical trial, it is impossible to blind a mother to whether she is giving birth at home or in a hospital, and most mothers are unwilling to be randomized to a home birth or hospital birth.

Lactobacillus reuteri for infants with colic: A double - blind, placebo - controlled, randomized clinical trial.

In households where women between the ages of 15 and 40 were pregnant, volunteer participants were administered either influenza vaccine or placebo as part of a randomized, placebo - controlled Phase 4 clinical trial.

A larger placebo - controlled clinical trial, sponsored by the National Institute of Mental Health (NIMH), is now underway.

High doses of vitamin D taken one hour after sunburn significantly reduce skin redness, swelling, and inflammation, according to double - blinded, placebo - controlled clinical trial out of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center.

The small trial was not randomized, double - blinded or placebo - controlled — the combination of which is considered the gold standard in clinical research.

The determination of each efficacy level was also based on the rigor and quantity of published studies on the drug class: to be in Level A, for example, a class of drugs must have been supported by at least two «Class I» studies — well - designed, double - blind, randomized, placebo - controlled clinical trials.

Researchers conducted a double - blind, randomized, placebo - controlled clinical trial to evaluate the safety and efficacy of pinaverium.

Motivated by their previous finding of the presence of P - glycoprotein overexpression in the nasal lining of patients with CRS with nasal polyps, the study authors conducted a randomized, double - blind, placebo - controlled clinical trial studying the use of low - dose Verapamil in 18 patients with CRS with nasal polyps.

Seventy women who were between the ages of 18 and 40 and had PCOS participated in the prospective randomized double - blind, placebo - controlled clinical trial.

Kosten recently completed the first placebo - controlled clinical trial for a cocaine addiction vaccine.

The resveratrol clinical trial was a randomized, phase II, placebo - controlled, double blind study in patients with mild to moderate dementia due to Alzheimer's disease.

In a controlled clinical trial published in 2005 in Gastroenterology, Weinstock and his colleagues gave 52 participants with colitis 2,500 pig whipworm eggs or a placebo every two weeks for three months.

However, the first Mayo trial, designed to be double - blind, randomised, placebo - controlled research and purporting to have duplicated the conditions in Cameron's clinical trial, disproved the Cameron - Pauling thesis.

The authors identified 35 clinical trials: 23 compared ACEIs with placebo or other active drugs (n = 32,827 patients) and 13 other trials compared ARBs with no therapy (controls)(n = 23,867 patients).

Using a randomized, placebo - controlled clinical trial (RCT) design, they randomized 48 participants into four equal groups of 12 people: low - to - moderate intensity, high - volume aerobic exercise (LO: HI); high - intensity, low - volume aerobic exercise (HI: LO); low - to - moderate intensity, low - volume aerobic exercise (LO: LO); and placebo (PLA) for an eight - week period.

The gold standard in clinical trials is a randomised, placebo - controlled study.

And it remains true that no homeopathic remedy has ever been shown to work in a large randomised placebo - controlled clinical trial.

In clinical trials conducted in patients with type 2 diabetes, sitagliptin has been shown to be effective in improving glycemic (blood sugar) control, cholesterol, lipoproteins and other health measures compared to placebo.

In the double - blind, placebo - controlled, randomized clinical trial, 16 individuals were randomly assigned to treatment (n = 8) or placebo (n = 8) groups.

Participants taking a placebo form the control group in blinded clinical trials.

Phase III Randomized, Placebo - Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy + / - One Year of Everolimus in Patients with High - Risk, Hormone Receptor - Positive and HER2 / neu Negative Breast Cancer.

* Results from a Randomized Placebo - Controlled Clinical Trial of a RBX2660 — a Microbiota - based Drug for the Prevention of Recurrent Clostridium difficile Infection — Erik R Dubberke — Clinical Infectious Dieases

BACKGROUND Whether endovascular stroke treatment improves clinical outcomes is unclear because of the paucity of data from randomised placebo - controlled trials.

Dr Brooks will be presenting the results of a single - center, randomized, double - blind, placebo - controlled clnical trial which was conducted to evaluate the safety, tolerability and clinical endpoint responsiveness of a drug called Ibudilast (or MN - 166) in subjects with the neurodegenerative condition, Amyotrophic Lateral Sclerosis (or ALS — also known as motor neuron disease; Click here to read a previous SoPD post about ALS and Click here to learn more about this clinical trial).

8/6/2008 Medicinal Marijuana Effective for Neuropathic Pain in HIV In a double - blind, placebo - controlled clinical trial to assess the impact of smoked medical cannabis, or marijuana, on the neuropathic pain associated with HIV, researchers at the University of California, San Diego School of Medicine found that repo... More...

Within monts, PRX002 became the subject of two randomized, double - blind, placebo - controlled clinical trials: a three - month single - dose trial (Phase Ia) and a six - month multiple - dose ascending trial (Phase Ib).

As director of the pediatric motor disorders research program at the University of Utah School of Medicine in Salt Lake City, she led the Project Cure SMA Investigators Network, a trial consortium that recently published the results of two placebo - controlled trials of the HDAC - blocking agent valproic acid, neither of which demonstrated much clinical advantage from the drug1, 2.

And despite the thousands of research papers published on turmeric, the reviewers were unable to find any double - blind, placebo - controlled clinical trials (the gold - standard of medical research) to support its myriad health claims.

Low - level laser in the treatment of patients with hypothyroidism induced by chronic autoimmune thyroiditis: a randomized, placebo - controlled clinical trial.

The outcomes of this preliminary study have resulted in the implementation of larger, placebo - controlled clinical studies to assess if individuals with heart failure as well as diabetes show improvement in their exercise capacity when given epicatechin - rich cocoa.

According to a double - blind, placebo - controlled, randomized 2009 study out of Brazil, women with clinical abdominal obesity (waist circumference of more than 88 cm) who used coconut oil daily for 12 weeks — in conjunction with a balanced, low - calorie diet and moderate exercise program — enjoyed a statistically greater reduction in waist circumference than those women taking soybean oil.

In a study published in 1999, A placebo - controlled clinical trial of L - tryptophan in premenstrual dysphoria, tryptophan was found to reduce symptoms of PMS when used in the luteal phase or second half of the cycle (i.e. after ovulation)

4) Montgomery SA, Thal LJ, Amrein, R. Meta - analysis of double blind randomized controlled clinical trials of acetyl - L - carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease.

In support of this hypothesis, the redox sensitivity of the basic insulin receptor signaling activity in vivo has been confirmed in a placebo - controlled clinical study of non-diabetic obese persons in whom basic (i.e., post-absorptive) insulin receptor signaling decreased after supplementation with relatively small doses of N - acetyl cysteine (200 mg NAC t.i.d. for a total daily dose of 0.6 g for 8 weeks).27

Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo - controlled, double - blinded, randomized clinical trial..

A number of placebo - controlled clinical studies have demonstrated Relora's ability to help ease the neurological symptoms associated with dieting.

However, there are a few that actually directly support body composition improvement (i.e., they're backed by peer - reviewed, placebo - controlled clinicals trials).

In general, there's a lack of peer - reviewed, placebo - controlled clinical trials for most supplements on the market.

The impact of metformin, oral contraceptives and lifestyle modification, on polycystic ovary syndrome in obese adolescent women in two randowmized, placebo - controlled clinical trials.

• KSM - 66 Ashwagandha clinical studies follow gold standards of substantiation: randomized, double - blind, placebo - controlled designs.

The U.S. National Institutes of Health counts 135 registered trials of curcumin in the last 15 years, according to the study authors, but not one double - blind, placebo - controlled clinical trial on curcumin can support all of the benefits we've been attributing to it, and when it comes to research that seemed to prove curcumin's effects on pancreatic and colon cancers, Alzheimer's disease, and radiation - induced rashes, it seems that the supposed benefits are all cracked up.

All were clinical trials that randomly assigned people with constipation to take either probiotics or a placebo (or other control treatment).