Sentences with phrase «placebo controlled phase»

Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III trial.

«Whenever possible, we try to do a very rigorous placebo control phase 2 study,» Scheller says.

Not exact matches

In households where women between the ages of 15 and 40 were pregnant, volunteer participants were administered either influenza vaccine or placebo as part of a randomized, placebo - controlled Phase 4 clinical trial.

Two hundred twenty - five people with schizophrenia, schizoaffective disorder or a mood disorder participated in the phase 3 randomized double blind, placebo - controlled trial.

Healthy adults mounted strong immune responses after receiving an investigational whole inactivated Zika virus vaccine, according to interim analyses of three Phase 1, placebo - controlled, double - blind trials conducted at Beth Israel Deaconess Medical Center (BIDMC), Walter Reed Army Institute of Research (WRAIR), and Saint Louis University School of Medicine.

A total of 2,129 patients with mild dementia due to Alzheimer's disease participated in the double - blind, placebo - controlled, phase 3 multicenter trial.

The resveratrol clinical trial was a randomized, phase II, placebo - controlled, double blind study in patients with mild to moderate dementia due to Alzheimer's disease.

The phase 2 program was comprised of two prospective, randomized double - blind, placebo - controlled, parallel group trials (ATHENA and ATHENA II).

This Phase 2a, randomised, double - blind, placebo - controlled multicentre study included 149 active PsA patients.

A Phase 3, Multicenter, Randomized, Double - Blind, Placebo - Controlled Study of AG - 120 in Previously - Treated Subjects with Nonresectable or Metastatic Cholangiocarcinoma with an IDH1 Mutation

A Phase 3, 12 - week, Double - Blind, Placebo - Controlled, Ran

ARandomized, Phase III, Double - Blind Placebo - Controlled Trial of Sunitinib as Maintenance Therapy in Non-Progressing Patients following an Initial Four Cycles of Platinum - Based Combination Chemotherapy in Advanced, Stage IIIB / IV Non-Small Cell Lung Cancer

Phase 2 Randomized, Double - Blinded, Controlled Study of Tucatinib vs. Placebo in Combination with Capecitabine and Trastuzumab in Patients with Pretreated Unresectable Locally Advanced or Metastatic HER2 + Breast Carcinoma

Phase III Randomized, Placebo - Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy + / - One Year of Everolimus in Patients with High - Risk, Hormone Receptor - Positive and HER2 / neu Negative Breast Cancer.

A Phase III, Multicenter, Randomized, Placebo - Controlled, Double - Blind Study Of Atezolizumab (Anti − PD - L1 Antibody) As Adjuvant Therapy In Patients With Renal Cell Carcinoma At High Risk Of Developing Metastasis Following Nephrectomy

A Phase III, Multicenter, Randomized, Placebo - Controlled Study of Atezolizumab (ANTI − PD - L1 Antibody) as Monotherapy and in Combination with Platinum - Based Chemotherapy in Patients with Untreated Locally Advanced or Metastatic Urothelial Carcinoma

In that randomized, double - blind, placebo - controlled, phase III trial, 561 patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who were in complete or partial response to platinum - based chemotherapy were treated with either rucaparib 600 mg orally twice daily (372 patients) or to placebo (189 patients).

The double - blind, variable - dose, placebo - controlled, crossover Phase IIa study was conducted in Iceland with 172 participants completing the trial.

Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo - controlled, phase 3 trial.

In their first - in - human, double - blind, placebo - controlled Phase I trial, Prothena scientists recruited 40 healthy people without PD to receive either placebo injections or or one of 5 doses of PRX002, ranging from 1 to 30 mg / kg.

Within monts, PRX002 became the subject of two randomized, double - blind, placebo - controlled clinical trials: a three - month single - dose trial (Phase Ia) and a six - month multiple - dose ascending trial (Phase Ib).

REFLECT is a randomized, double - masked, placebo - controlled Phase III trial evaluating the safety and efficacy of bilateral injections of GS010 in patients with < 1 year of onset of vision loss in LHON.

A Double Blind Placebo - Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients with Stage 0 - III Colon or Rectal Cancer Phase III Preventing Adenomas of the Colon with Eflornithine and Sulindac (PACES)

In this double - blind, placebo - controlled phase II study (NCT00848692), 30 CFS patients were randomised to either Rituximab 500 mg / m2 or saline, given twice two weeks apart, with follow - up for 12 months.

A double - blind, placebo - controlled phase III study has been designed to include 660 patients with treatment - naive, stage III / IV melanoma with injectable lesions.

In a study published in 1999, A placebo - controlled clinical trial of L - tryptophan in premenstrual dysphoria, tryptophan was found to reduce symptoms of PMS when used in the luteal phase or second half of the cycle (i.e. after ovulation)

A randomized, double - blind, placebo - controlled study of luteal phase dydrogesterone (Duphaston) in women with minimal to mild endometriosis.

The approval was supported by two placebo - controlled Phase III clinical studies comparing Fanapt ™ to placebo and active control in patients with schizophrenia, as well as safety data from more than 3,000 patients.