Sentences with phrase «placebo injections of»

They vaccinated another five calves with a post-F protein, while a third group of five calves received two placebo injections of saline.

Not exact matches

Researchers report that the only substantial difference in safety outcomes between the placebo and bococizumab groups was injection site reactions, which is also the result of the immunologic response in some patients.

Safety was generally similar between inclisiran and placebo apart from a small numerical excess of injection site reactions with the study drug.

For 8 weeks, they fed normal mice a high - fat diet and gave them daily injections of either TNP, a well - known IP6K1 inhibitor, or a placebo.

In addition, they were randomly assigned, in a 2 - to - 1 ratio, to a once - daily injection with either 3 mg of liraglutide (2,487 subjects) or placebo (1,244 subjects) for 56 weeks.

In the four weeks after the first treatments, people had about 15 percent fewer days of headache compared with a placebo or dummy injection.

In addition, they were randomly assigned, in a 2 - to - 1 ratio, to a once - daily injection with either 3 mg of liraglutide or placebo for 56 weeks.

The study involved 10 275 healthy children aged 2 to 14 years who were randomly assigned to receive three injections of the CYD - TDV vaccine (6851) or a placebo (3424) at 0, 6, and 12 months, and followed for up to 2 years.

In the trials, a total of 67 healthy adult volunteers received two injections, four weeks apart: 55 received the ZPIV vaccine and 12 received a placebo.

Its staff help principal investigators to work out the tiniest details of doses and delivery methods, whether they are preparing a parotid - gland injection or putting a film coating on a placebo pill to make it indistinguishable from the active drug in the trial.

The researchers followed 60 people with Parkinson's disease at the National Hospital for Neurology and Neurosurgery (NHNN) as they used either a once - weekly injection of exenatide for 48 weeks, or a placebo, in addition to their regular medications.

Each subject received six weekly injections with either a placebo or one of two doses of active vaccine.

In comparison, mice which received a placebo injection had no memory of objects seen the day before.

The women were randomized to receive two injections of the steroid betamethasone or a placebo, given 24 hours apart.

A clinical trial in which volunteers were infected with dengue virus six months after receiving either an experimental dengue vaccine developed by scientists from the National Institutes of Health (NIH) or a placebo injection yielded starkly contrasting results.

Paul D. Miller, M.D., of the Colorado Center for Bone Research, Lakewood, Colo., and colleagues randomly assigned postmenopausal women with osteoporosis to receive daily injections for 18 months of placebo (n = 821); abaloparatide (n = 824); or teriparatide (n = 818).

Among postmenopausal women with osteoporosis at risk of fracture, daily injection of the drug abaloparatide for 18 months significantly reduced the risk of new vertebral and nonvertebral fractures compared with placebo, according to a study appearing in the August 16 issue of JAMA.

The experiment was divided into two phases: Phase 1 (30 stimuli; duration 5 min) was followed by a submucosal injection of the anaesthetic articaine 4 % (group A) or 0.9 % NaCl as placebo (group P) at the left mental foramen.

For four days, some animals received injections of CRH while others received a placebo.

Two weeks after the rats sustained their injuries, Schwartz's group found that the number of surviving cells in the damaged nerves of these rats was three times higher on average than in rats with similar damage that received a placebo injection.

In subsequent tests using an immunodeficient mouse model infected by Zika, intravenous injections of sofosbuvir significantly reduced viral loads in blood serum compared to a placebo group.

Five minutes before injection of [11C] raclopride, subjects were i.v. injected with placebo (3 mL of saline) on one day and with MP (0.5 mg / kg) on another day.

Participants were randomized to received 4 weeks of subcutaneous (under the skin) injections of GM - CSF (leukine), 3 times a week (n = 80), or placebo (n = 79).

An additional cohort of non-pregnant mice (n = 20) received placebo injections at the same time points.

In their first - in - human, double - blind, placebo - controlled Phase I trial, Prothena scientists recruited 40 healthy people without PD to receive either placebo injections or or one of 5 doses of PRX002, ranging from 1 to 30 mg / kg.

REFLECT is a randomized, double - masked, placebo - controlled Phase III trial evaluating the safety and efficacy of bilateral injections of GS010 in patients with < 1 year of onset of vision loss in LHON.

REFLECT is a multi-center, randomized, double - masked, placebo - controlled study to evaluate the safety and efficacy of bilateral injections of GS010 in subjects with LHON due to the NADH dehydrogenase 4 (ND4) mutation.

Throughout the trial, a placebo arm has been used, to help distinguish drug effects from the effects of being in the trial, such as the injection procedure.

METHODS: Three hundred seventy - two patients with mild to moderate AD were randomized to receive IM injections of AN1792 or placebo (4:1) at baseline and at months 1, 3, 6, 9, and 12 in a multicenter Phase II safety, tolerability, and pilot efficacy study.

And don't they realize that even if a clinical trial fails to demonstrate that a drug or surgery or alternative medicine treatment is better than a placebo, that doesn't mean it doesn't «work» when 18 to 80 % of the time, the body heals itself when given a sugar pill or saline injection in a clinical trial.

Each dietary category was further divided into 2 groups either being administered a weekly injection of testosterone or a placebo injection.