«Cold water in the left ear significantly increased patients» insight and awareness of their schizophrenia, which we measured 30 minutes after the test, compared with the sham or
placebo treatment using room temperature water,» says Dr. Gerretsen.
Not exact matches
Placebos are
used to help accurately measure clinical responses / outcomes when studying the effects of medications, therapies, and other
treatments.
In this new study and for the first time, scientists
used functional magnetic resonance imaging (fMRI) combined with a standard clinical trial design to derive an unbiased brain - based neurological marker to predict analgesia associated with
placebo treatment in patients with chronic knee osteoarthritis pain.
In a related Editor's Note, Deborah Grady, M.D., M.P.H., a deputy editor of JAMA Internal Medicine, writes: «It is possible that
treatment beyond one year would result in better outcomes, but these data provide no support for
use of higher - dose cholecalciferol replacement therapy or indeed any dose of cholecalciferol compared with
placebo.»
TRINOVA - 2 is evaluating pegylated liposomal doxorubicin in combination with either
placebo or trebananib in previously treated patients with ovarian cancer while TRINOVA - 3, also known as ENGOT - Ov2 and Gynecologic Oncology Group — 3001, is studying the
use of trebananib in front - line
treatment adding it to carboplatin / paclitaxel.
Dr Jones, said: «This new meta - analysis shows that baclofen is no more effective than
placebo on a range of key outcome measures, suggesting that the current increasing
use of baclofen as a
treatment for alcohol
use disorders is premature.»
The study, «Intravenous augmentation
treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double - blind,
placebo - controlled trail,» published online will change how clinicians understand this
treatment and encourage them to consider its early
use before the condition causes severe emphysema.
Using a sample of 10 resistance - trained men in their early 20s, protein supplementation consisted of 3
treatment groups: whey protein isolate, soy protein isolate, or a maltrodextrin
placebo control.
Some trial participants were randomly assigned to
use inhalers daily while some
used them intermittently; some received
placebos and some received no
treatment.
The patients
used each
treatment (candesartan, propranolol or
placebo) for 12 weeks, and also underwent four weeks before start and between the
treatment periods without any medication at all.
Yet concerns persist and many are «overinflated,» they add, and list recent studies supporting the
use of lithium, once labelled a «toxic
placebo,» and antipsychotics, and
treatments for mood disorders.
They also found some evidence supporting the
use of techniques such as acupuncture and spinal manipulation for acute and chronic pain — although it should be noted that several researchers have questioned whether these
treatments are superior to
placebo or sham therapies.
Among cigarette smokers not willing or able to quit smoking in the next month but willing to reduce with the goal of quitting in the next 3 months,
use of the nicotine addiction medication varenicline for 24 weeks compared with
placebo produced greater reductions in smoking prior to quitting and increased smoking cessation rates at the end of
treatment and at 1 year, according to a study in the February 17 issue of JAMA.
A pooled analysis of data from two randomised trials comparing vitamin E versus
placebo, and the
placebo group from another trial comparing vitamin E
use versus non-
use, demonstrates that the efficacy of vitamin E is comparable to other
treatments for NASH, including pioglitazone, metformin and obeticholic acid.
The researchers found that the addition of vitamin D3 to ciclesonide did not significantly reduce the rate of first
treatment failure (a composite outcome of decline in lung function and increases in
use of beta - agonists, systemic steroids, and health care utilization) compared with
placebo; 28 percent and 29 percent of participants in each group, respectively, experienced at least 1
treatment failure during 28 weeks.
These would make
use of factors contributing to the
placebo effect, applying them specifically to the
treatment of depression.
Instead, the team chose only studies that were
placebo - controlled,
used tDCS as a daily medical
treatment, and involved at least 10 participants.
«Both physical functioning and quality of life are severely affected, and while many
treatments are
used to relieve symptoms and try to get the disease under control, this largest set of
placebo - controlled information to date clearly shows that improvement can result for patients.»
The drugs and
placebo were provided to paramedics in indistinguishable boxes containing three syringes, each containing a third of the maximum total dose, to ensure that neither patients nor care providers knew which
treatment was
used for a given patient.
In many trials, some participants are randomly assigned to the «control» group and receive an inactive «
placebo»
treatment or a standard intervention currently in
use; sometimes the control subjects are later given a chance to try the experimental
treatment.
Placebos are rarely
used in cancer
treatment clinical trials.
The study looked at the effect of dietary supplementation
using 2,000 international units of nonprescription vitamin E daily in a large group of elderly Alzheimer's patients and compared their results over an average of around two years to similar patients who received a
placebo, a pharmaceutical marketed as a «
treatment» for Alzheimer's disease (memantine), or a combination of memantine along with vitamin E.
The men were treated with a Maca extract of 2400 mg or a
placebo, and the effect of the Maca
treatment was tested
using the International Index of Erectile Function (IIEF - 5) before and after 12 weeks of
treatment.
BOOKS (67) http://www.amazon.com/Bioelectromagnetic-Healing-Rationale-its-
Use/dp/0964107058 Bioelectromagnetic Healing: A Rationale for its
Use by Thomas Valone 2003 (68) http://www.amazon.com/Energy-Medicine-Scientific-James-Oschman/dp/0443062617 Energy Medicine: The Scientific Basis by James L. Oschman 2000 Therapeutic
Uses of Pulsed EMF (69)(70)(71)(72)(73)(74)(75) http://ajp.psychiatryonline.org/cgi/content/full/163/1/88 A Randomized, Controlled Trial of Sequential Bilateral Repetitive Transcranial Magnetic Stimulation for
Treatment - Resistant Depression, Am J Psychiatry 163:88 - 94, January 2006 (70) http://www.ondamed.net/publication/html/en/article15.html Impulse magnetic - field therapy for migraine and other headaches: a double - blind,
placebo - controlled study.
Extensive
placebo - controlled clinical trials will be needed before metformin can be
used as a standard cancer
treatment.
When no diagnosis was found, a
placebo treatment was
used.
Sixteen systematic reviews provided data on 17 comparisons with inactive interventions (
placebo, sham interventions or waiting list).30 — 32 35 — 37 39 — 43 45 — 50 figure 2 provides an overview of
treatment effects of non-pharmacological and common pharmacological
treatments for MDD when compared with inactive interventions
using standardised mean differences.
The
use of a single antidepressant in an open - trial design without a
placebo control did not allow us to rule out that maternal remission was due to nonspecific
treatment effects or whether the relation of maternal remission to children's outcomes may have been different if another medication or psychotherapy had been
used.
Hollander et al
used a double blind,
placebo controlled design to examine the efficacy of a 10 week
treatment of lithium on the clinical and cognitive features of gambling in pathological gamblers with bipolar spectrum disorder.
Compared with
placebo,
treatment of depressed systolic heart failure patients with escitalopram will result in a significant improvement in symptoms of depression at six months, when measured
using the Hamilton Depression Rating Scale.
Compared with
placebo,
treatment of depressed systolic heart failure patients with escitalopram will result in a significant improvement in symptoms of depression at six months, when measured
using the Cardiac Depression Scale.
This study (NIDA #R01DA025616) is a randomized clinical trial (RCT) that will compare an experimental
treatment (OutPatient Treatment for Adolescents) to an «active placebo» on key indices (drug use; mental health; behavioral, school, peer, and family functioning; and consumer satisfaction) from pre-treatment through 18 months in order to evaluate its efficacy for youth referred to outpatient treatment of co-occurring substance use and internalizing
treatment (OutPatient
Treatment for Adolescents) to an «active placebo» on key indices (drug use; mental health; behavioral, school, peer, and family functioning; and consumer satisfaction) from pre-treatment through 18 months in order to evaluate its efficacy for youth referred to outpatient treatment of co-occurring substance use and internalizing
Treatment for Adolescents) to an «active
placebo» on key indices (drug
use; mental health; behavioral, school, peer, and family functioning; and consumer satisfaction) from pre-
treatment through 18 months in order to evaluate its efficacy for youth referred to outpatient treatment of co-occurring substance use and internalizing
treatment through 18 months in order to evaluate its efficacy for youth referred to outpatient
treatment of co-occurring substance use and internalizing
treatment of co-occurring substance
use and internalizing problems.
Two
treatment conditions and two control groups were
used in a variant of the Solomon four - group study design that included an attention -
placebo manipulation instead of a posttest - only control group.