Sentences with phrase «plaque burden»

Quantification of amyloid plaque burden was based on the image captured by immunohistochemical staining with antibody 6E10.

Cortical plaque burdens in Tg2576, APPSwe PS1Δ E9, and 5XFAD mice eventually far exceeded those measured in the human cohort.

Having increased prevalence of carotid plaque burden or coronary artery calcium are signs of atherosclerosis or diseased arteries.

Novel 3D vascular ultrasound imaging technology allowed researchers to quantify the amount of carotid artery plaque burden lining each patient's carotid arteries in their neck, while a coronary artery calcium score CT scan allowed for the identification of any narrowing or hardening of the coronary arteries due to the buildup of fatty cholesterol and calcified plaque.

Since some compounds that reduce memory loss in AD mice reduce the Aβ plaque burden, we next examined plaque size and density in the hippocampus of J147 - treated and control aged huAPP / PS1 mice.

BACKGROUND: AN1792 (beta - amyloid [Abeta] 1 - 42) immunization reduces Abeta plaque burden and preserves cognitive function in APP transgenic mice.

We also compared the dense - core plaque burdens in the mice to those measured in a set of pathologically - confirmed AD cases from the Nun Study.

provide a direct quantitative comparison of amyloid plaque burdens and plaque sizes in four lines of AβPP transgenic mice.

The study shows those apparently healthy individuals identified with increased carotid plaque burden and coronary artery calcium were two to three times more likely to have an adverse event such as an artery blockage, or a piece of plaque becoming loose causing a heart attack or stroke.

«Healthy patients with elevated calcium and plaque burden are at increased risk of experiencing adverse cardiovascular events in even a short period of just three years.»

We found that the plaque burdens among the transgenic lines varied by an order of magnitude: at 15 months of age, the oldest age studied, the median cortical plaque burden in 5XFAD mice was already ∼ 4.5 times that of 21 - month - old Tg2576 mice and ∼ 15 times that of 21 — 24 - month - old rTg9191 mice.

Keywords: Alzheimer's disease, amyloid plaque, amyloid - β protein precursor, plaque burden, plaque size, Thioflavin S, transgenic mouse

Plaque burden was reduced in SUS - treated AD mice compared to sham - treated animals, and cleared plaques were observed in 75 % of SUS - treated mice.

«zero plaque burden» is the result on the Cardio - risk report... and my arterial age is YOUNGER than my actual age according to the report.

It drew mass attention when researchers were astonished to find that low doses of the golden spice significantly reduced amyloid plaque burden — something brain health doctors had been seeking to do for decades.