The study was performed in 2002 and found that «
plasma amino acid elevation induces skeletal muscle insulin resistance in humans» (18).
Not exact matches
These results concur with previous data indicating that only moderate insulin
elevations (15 — 30 mU / L) are required to maximize net muscle protein balance in the presence of elevated
plasma amino acids [96].
This is in line with earlier experimental
elevations of
plasma amino acids by infusion, which resulted in impaired insulin - stimulated glucose disposal and insulin - mediated suppression of (hepatic) glucose production (36,37).