Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward
plasma cell differentiation.
Not exact matches
«Together,» explains Dr. Ramiro, «the results indicate that CTCF is important for maintaining the germinal center
differentiation program and prevents premature
differentiation towards
plasma cells.»
Anaplastic, plasmablastic, and plasmacytic plasmacytomas of mice: relationships to human
plasma cell neoplasms and late - stage
differentiation of normal B
cells.
CD20 is a B - lymphocyte surface molecule that is widely expressed during B -
cell ontogeny, from early pre-B-
cell developmental stages until final
differentiation into
plasma cells.
Atherosclerosis is initiated by high
plasma cholesterol leading to monocyte entry into the artery wall and
differentiation into macrophages, which take up lipoprotein cholesterol to become lipid engorged foam
cells.
These include a reduction in B
cell differentiation to
plasma cells and a reduced proliferation of T
cells.
Unlike normal
plasma cells, the malignant
plasma cells look large and round with a high mitotic index (measure of the proliferation of a
cell population) in early stages of cellular
differentiation.