Sentences with phrase «plasma cell disorder»
KLF9 - Novel Transcriptional Regulator of Multiple Myeloma Chemotherapy Resistance Multiple myeloma (MM) is a plasma cell disorder that accounts for approximately 10 % of all hematologic malignancies.
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In a related editorial, Niklhil C. Munshi, M.D., of the Dana - Farber Cancer Institute, Boston, writes: «The study by Landgren et al has brought clarity to the risk of AO [Agent Orange] exposure and plasma cell disorder.
Not exact matches
The new findings build on prior research from the Dhodapkar lab demonstrating that patients with Gaucher disease, an inherited lipid storage disorder, have a significant increased risk for developing myeloma; and the discovery of a subset of lipid - reactive immune cells, called type II NKT - TFH, that promote the development of plasma cells.
Multiple myeloma is preceded by a blood disorder called monoclonal gammopathy of undetermined significance (MGUS) in which abnormal plasma cells produce many copies of an antibody protein.
Most MGUS cases are never diagnosed; MGUS is characterized by a detectable M protein without evidence for end - organ damage or other related plasma cell or lymphoproliferative disorders.
The analysis of cell free DNA in maternal plasma has led to widespread introduction of less invasive testing for aneuploidy, but less so for monogenic disorders.
INFLAMMATORY BOWEL DISEASE (IBD) The inflammatory bowel diseases (IBD) are the most common causes of chronic vomiting and diarrhea in dogs, and refer to a group of idiopathic, chronic gastrointestinal tract disorders, characterized by infiltration of the lamina propria by lymphocytes, plasma cells, eosinophils, macrophages, neutrophils, or combinations of these cells.12 The diagnosis of IBD requires the comprehensive exclusion of potential causes of gastrointestinal inflammation, including intestinal parasites, small intestinal bacterial overgrowth, bacterial enterocolitis, dietary intolerances or allergies, and neoplasia.12 Failure to eliminate known causes of gastrointestinal inflammation which can mimic IBD can result in frustration for the owner and clinician due to poor responsiveness of the animal to dietary or pharmacologic therapy.