Low - fat diets do not lower
plasma cholesterol levels in healthy men compared to high - fat diets with similar fatty acid composition at constant caloric intake
[9]-
Plasma cholesterol levels in rabbits fed low fat, low cholesterol diets.
(D) Fasting
plasma cholesterol levels in mutant mice on a high - fat diet treated for 5 weeks with control or ApoC - III ASO (n = 5 — 10 / group).
The lipoprotein transport system holds the key to understanding the mechanisms by which genes, diet, and hormones interact to regulate
the plasma cholesterol level in man.
Not exact matches
Dr. Jiang found that LPCAT3 deficiency significantly reduces polyunsaturated PC
levels in the
plasma membrane of the cells that line the intestines, which
in turn reduces lipid absorption and decreases
levels of lipids (
cholesterol, triglyceride, and phospholipid)
in circulation.
Researchers at the University of Chicago have found an unsuspected link between the immune system and high
plasma lipid
levels (
cholesterol and triglycerides
in the blood)
in mice.
The iLpldf mice presented with elevated
plasma TG and
cholesterol levels (Supplemental Figure 5, C and D, respectively), along with a dramatic increase
in VLDL TGs and a reduction
in HDL
cholesterol levels (Supplemental Figure 5, E and F), as observed
in patients with LPL deficiency (16).
Total
cholesterol and TG
levels in plasma were determined using kits from Genzyme or Thermo Fisher Scientific.
ApoE as a major causative factor and therapeutic target
in Alzheimer's disease and other neurodegenerative disorders; small - molecule structure correctors to convert apoE4 to apoE3 and reverse the detrimental effects of apoE4 on mitochondria and the cytoskeleton; small - molecule protease inhibitors to block the formation of toxic fragments of apoE4;
Plasma lipoprotein metabolism regulation involving apoE and apoB;
cholesterol homeostasis modulation by lipoprotein receptors controlling lipoprotein clearance by the liver;
Plasma HDL
cholesterol (HDL - C) metabolism
in the progression of atherosclerosis; the genetic epidemiology of the metabolic syndrome and low HDL - C
levels established by the Turkish Heart Study.
Nevertheless, the reduction
in plasma TG and
cholesterol levels induced by ApoC - III ASO did not enhance hepatic steatosis (Figure 5, E and F) or induce weight gain or loss
in the mice (Supplemental Figure 4).
«While the major CVD benefit of statins is due to reduction
in plasma low density lipoprotein
cholesterol (LDL - C), [2] statins also produce moderate increases, ranging from 4 % to 10 %,
in levels of high density lipoprotein
cholesterol (HDL - C).
Increased
plasma lycopene
levels have also been correlated with lower cardiovascular disease and lower
cholesterol — since studies are showing that lycopene
in the diet can help to increase the breakdown of low - density lipoproteins (LDL
cholesterol, the kind that builds up)
in the body.
Depression of
cholesterol levels in human
plasma following ethylenediamine tetracetate and hydralazine.
The amino acids and plant phosphatides and phytosterols
in GenFX can with exercise and a balanced diet help maintain muscle mass and strength, decrease fat deposits, keep
cholesterol and LDL
levels at low healthy
levels in plasma, and help maintain or improve memory and cognition.
In relation to CVD, elevated blood pressure has been shown to be positively associated with higher intakes of red and processed meat, even though the mechanism is unclear, except that possibly meat may substitute for other beneficial foods such as grains, fruits, or vegetables.32 Mean plasma total cholesterol, low - density lipoprotein cholesterol, very - low - density lipoprotein cholesterol, and triglyceride levels were found to be decreased in subjects who substituted red meat with fish.33, 34 Vegetarians have lower arachidonic, eicosapentaenoic, and docosahexaenoic acid levels and higher linoleate and antioxidant levels in platelet phospholipids; such a biochemical profile may be related to decreased atherogenesis and thrombogenesis.34 -
In relation to CVD, elevated blood pressure has been shown to be positively associated with higher intakes of red and processed meat, even though the mechanism is unclear, except that possibly meat may substitute for other beneficial foods such as grains, fruits, or vegetables.32 Mean
plasma total
cholesterol, low - density lipoprotein
cholesterol, very - low - density lipoprotein
cholesterol, and triglyceride
levels were found to be decreased
in subjects who substituted red meat with fish.33, 34 Vegetarians have lower arachidonic, eicosapentaenoic, and docosahexaenoic acid levels and higher linoleate and antioxidant levels in platelet phospholipids; such a biochemical profile may be related to decreased atherogenesis and thrombogenesis.34 -
in subjects who substituted red meat with fish.33, 34 Vegetarians have lower arachidonic, eicosapentaenoic, and docosahexaenoic acid
levels and higher linoleate and antioxidant
levels in platelet phospholipids; such a biochemical profile may be related to decreased atherogenesis and thrombogenesis.34 -
in platelet phospholipids; such a biochemical profile may be related to decreased atherogenesis and thrombogenesis.34 - 36
Evidence from some studies48 49 50 51 52 53 54 55 56 has indicated that a high - carbohydrate diet compared with a high - unsaturated - fat diet (ie, MUFA), both of which are low
in SFA and
cholesterol, can cause an increase
in plasma triglyceride concentrations and a decrease
in HDL
cholesterol levels.
However, when a modest
level of Î ² - glucan (3 g / d) was provided to 62 healthy adults with mild to moderate hyperlipidemia, there was no significant reduction
in plasma total or LDL
cholesterol concentra - tions (Lovegrove et al., 2000).