Sentences with phrase «plasma homocysteine»
In simpler terms, "plasma homocysteine" refers to a substance called homocysteine that is found in our blood. Homocysteine levels can sometimes be used as a marker to measure the risk of certain health problems, such as heart disease. Full definition
In a sample of 1,092 men and women without dementia followed for an average of 10 years, those with higher plasma homocysteine levels at baseline had a significantly higher risk of developing Alzheimer's disease and other types of dementia.
lpi.oregonstate.edu
Inadequate dietary intake of methyl groups leads to hypomethylation in many important pathways, including 1) disturbed hepatic protein (methionine) metabolism as determined by elevated plasma homocysteine concentrations and decreased S - adenosylmethionine concentrations, and 2) inadequate hepatic fat metabolism, which leads to steatosis (fatty accumulation) and subsequent plasma dyslipidemia.
Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism.
+ / + - Homozygotes for this variant allele in the CTH gene had significantly higher plasma homocysteine levels than other genotypes in a cohort of 496 Caucasian individuals.
Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects
However, when methionine - rich diets are used to induce hyperhomocysteinemia... Mice fed methionine - rich diets had significant atheromatous pathology in the aortic arch even with normal plasma homocysteine levels, whereas mice fed B vitamin - deficient diets developed severe hyperhomocysteinemia without any increase in vascular pathology.
Several factors influence plasma homocysteine levels, such as intake of folic acid and vitamin B12, age, gender, heredity, smoking, hypertension, and physical activity39.
In addition, no causal relationship has been established between high total plasma homocysteine levels (tHCYs) and cardiovascular disease43.
Meat - eating populations have been shown to maintain lower plasma homocysteine concentrations than nonmeat eaters (128,129).
Orally administered betaine has an acute and dose - dependent effect on serum betaine and plasma homocysteine concentrations in healthy humans.
Specifically, those with plasma homocysteine levels greater than 14 μmol / L had nearly double the risk of developing Alzheimer's disease (47).
RESULTS: Plasma homocysteine levels were not affected by diet.
Low serum levels of certain B vitamins (folate and vitamins B12 and B6) have been associated with elevated plasma homocysteine levels in several studies and with an increased risk of dementia in a few investigations.38 - 42 In our study, the observed association between plasma homocysteine and risk of dementia was not significantly altered by adjustment for the plasma levels of these vitamins (Table 3).
Vegetarians and cardiovascular risk factors: hemostasis, inflammatory markers and plasma homocysteine