Sentences with phrase «plasma levels of»

These changes are important because both stressors and depression can sensitize the inflammatory response in such a way that they produce heightened responsiveness to stressful events as well as antigen challenge.25, 27,28,60 Furthermore, more frequent or persistent stress - related changes in plasma levels of these key cytokines have broad implications for health; elevated levels of proinflammatory cytokines have been linked to a variety of age - related disease, including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes mellitus, certain cancers, and frailty and functional decline.29 Moreover, inflammatory activation can enhance development of depressive symptoms.30, 31 Thus, relationships characterized by hostility, repeated conflicts, and heightened IL - 6 levels could have negative consequences for both physical and mental health.

Although greater early local production of proinflammatory cytokines at wound sites is beneficial because it is associated with enhanced healing, greater systemic production of proinflammatory cytokines can represent a maladaptive response.24 Both physical and psychological stressors can provoke transient increases in plasma levels of proinflammatory cytokines, particularly IL - 6,25 as can negative emotions like depression and anxiety.26 - 28 More frequent or persistent stress - related changes have broad implications for physical and mental health; sustained elevated levels of proinflammatory cytokines have been linked to a variety of age - related diseases, including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes mellitus, certain cancers, and frailty and functional decline.29 - 31

The journal «Psychosomatic Medicine» reports that in one study of 38 cohabiting couples, those with higher perceptions of partner support from warm contact — which included hugging — showed higher blood plasma levels of oxytocin, the hormone responsible for bonding and attachment.

All dogs regardless of breed that exhibit symptoms of prolonged bleeding times or spontaneous bleeding may be tested for plasma levels of vWf to confirm a diagnosis.

Plasma levels of closely related tricyclic antidepressants have been reported to be increased by the concomitant administration of hepatic enzyme inhibitors (e.g., cimetidine, fluoxetine).

Missing a dose will lead to some changes in the plasma levels of the active ingredient of Apoquel.

Caffeinated coffee increased plasma levels of granulocyte - colony stimulating factor (GCSF), which seemed to improve the cognitive performance of AD transgenic mice with the recruitment of bone marrow cells, enhanced synaptogenesis, and increased neurogenesis.

Low serum levels of certain B vitamins (folate and vitamins B12 and B6) have been associated with elevated plasma homocysteine levels in several studies and with an increased risk of dementia in a few investigations.38 - 42 In our study, the observed association between plasma homocysteine and risk of dementia was not significantly altered by adjustment for the plasma levels of these vitamins (Table 3).

The results show quicker and higher plasma levels of HMB with improved utilization by the tissues.

Low plasma levels of zinc have been observed in congenital diseases such as sickle cell anemia (Ballester et al. 1986), Down's syndrome (Licastro et al. 1992) and acrodermatitis enteropathica.

Reyes - Izguierdo T, Nemzer B, Shu C, Huynh L, Argumedo R, Keiler R, Pietrzkowski Z. Modulatory effect of coffee fruit extract on plasma levels of brain - derived neurotrophic factor in healthy subjects.

Research shows it may produce higher plasma levels of creatine than monohydrate, but this doesn't translate into greater muscle absorption or performance enhancement.

Despite the small size of the pilot study, researchers demonstrated reduced plasma levels of kynurenine with increased tryptophan levels.

(iii) Many cancer patients, in particular those with advanced stages of the disease, exhibit altered whole - body metabolism marked by increased plasma levels of inflammatory molecules, impaired glycogen synthesis, increased proteolysis and increased fat utilization in muscle tissue, increased lipolysis in adipose tissue and increased gluconeogenesis by the liver.

The acne - ridden men had blood and plasma levels of 1.59 and 1.22 respectively, whereas the healthy men had levels of 1.80 and 1.36.

Monocyte and lymphocyte release of proinflammatory cytokines and plasma levels of C - reactive protein (CRP) were assessed.

Phenylketonunics, who have a genetic error of phenylalanine metabolism, have elevated serum plasma levels of phenylalanine up to 400 times normal.

Leucine and BCAAs acids do spike insulin but they increase plasma levels of insulin levels temporarily and they have almost no effect on glucose or urea nitrogen [xiii].

Yasmina Ykelenstam: But the — the testing that exists at the moment for histamine intolerance is only the — the plasma levels of histamine.

Patients with hypothyroidism have significantly higher plasma levels of homocysteine (16).

Accordingly, plasma norepinephrine (NE) concentrations, NE appearance rate, and plasma levels of triiodothyronine (T3), free T3, and total thyroxine (T4) were lower after training.»

2) Eur J Clin Nutr, 2009 Sep, 63 (9): 1076 - 83, Epub 2009 May 27, «Differential effects of casein versus whey on fasting plasma levels of insulin, IGF - 1 and IGF - 1 / IGFBP - 3: results from a randomized 7 - day supplementation study in prepubertal boys»

Sebekova K, Krajcoviova - Kudlackova M, Schinzel R, Faist V, Klvanova J, Heidland A. Plasma levels of advanced glycation end products in healthy, long - term vegetarians and subjects on a western mixed diet.

One group of men who were given wave therapy also saw an increase in plasma levels of testosterone, and a decrease in the stress hormone cortisol.

DHA is especially important for kids because studies have shown that lower plasma levels of this oil are associated with poorer reading ability and working memory performance.

(C) Fasting plasma levels of 3 - hydroxybutyrate (3 - HB) in mutant mice treated for 4 weeks with control or ApoC - III ASO (n = 3 — 9 / group).

Since SLC6A14 is up - regulated in patients with ulcerative colitis indicating potential association between inflammation and the transporter [18], we measured the plasma levels of various cytokines, but again failed to detect major changes in most of the cytokines analysed (result not shown).

The results suggest that elevated plasma levels of inflammatory biomarkers, including complement proteins, associate with polygenic risk scores in AD, further strengthening the link between genetic and biomarker disease predictors and indicating a potential role for these markers in disease prediction and patient stratification in AD.

We monitored the plasma levels of amino acids in wild - type and knockout mice and found no significant differences between the two genotypes (Table 1).

Brain serotonin content is dependent on plasma levels of the essential amino acid tryptophan.

Plasma levels of bacterial antigen specific IgA anti-Hsp60 antibodies were also lower in the patient group (P = 0.0001).

Dosing of mebendazole of 30 - 87 mg / kg / day in humans resulted in plasma levels of 120 -218 nM (260 nM for continuous administration) with coefficients of variation ranging from 27 to 72 %.

Plasma levels of markers for arteriosclerosis and indices of inflammation in 50 patients with severe periodontitis were compared with those in 46 healthy cases.

Plasma levels of sNKG2D - L, and verexpression of ADAM10, correlate with disease progression and are prognostic marker in some hematologic malignancies, including Hodgkin lymphomas (HL).

In alligators, plasma levels of perfluorooctane sulfonate (PFOS) ranged from 1,360 to 452,000 parts per trillion.

In the U.S. study, median plasma levels of certain PFAAs were highest in alligators on Kiawah Island, an Atlantic Ocean barrier island southwest of Charleston, South Carolina, and on Merritt Island in Florida.

No decrease was observed in patients whose plasma levels of HIV had already been reduced through ART.

These outcomes were determined by measuring plasma levels of a liver enzyme called alanine aminotransferase (reduced by approximately 55 percent) and levels of liver triglycerides (reduced by approximately 21 percent).

The investigators measured four Aβ peptides and found that no significant differences in plasma levels of any of the Aβ peptides were found among the three genetic groups.

The Brain Trauma Indicator measures blood plasma levels of the UCH - L1, a protein scientists believe helps dispose of cellular waste in the brain, and GFAP, a structural protein found in non-neuronal cells called astrocytes.

Plasma levels of this biomarker rose with kidney deterioration in patients with MMA, and may serve as a valuable indicator of MMA kidney disease progression in the clinic.

The test measures blood plasma levels of a sticky protein called amyloid - beta.

The plasma levels of these drugs are extremely low, and thus milk levels would be even lower.

One study of 16 women indicated decreased plasma levels of prolactin especially in the luteal phase of the menstrual cycle.11

Differences in release of insulin and other pancreatic and gut hormones have also been observed between breastfed and formula - fed infants, with formula feeding leading to higher plasma levels of insulin which in turn would stimulate fat deposition and early development of adipocytes, the cells that store fat (18).

Increased plasma levels of oxytocin in response to afferent electrical stimulation of the sciatic and vagal nerves and in response to touch and pinch in anaesthetized rats.

Additionally, the kangaroo diet led to a rise in the plasma levels of the polyunsaturated fatty acid arachidonic acid, which is high in the meat, and which has a positive effect on blood flow.

In the U.S., the average blood plasma level of gamma - tocopherol is four or more times higher than those of European and Scandinavian countries that consume sunflower and olive oil, Cook - Mills noted.

Fortunately, that did not prove an issue in the phase 1 trial, which showed that a single infusion of the VRC01 antibody could suppress the blood plasma level of HIV in infected individuals not taking antiretroviral therapy.

This study studied the relationship between plasma level of insulin - like growth hormone I (IGF - I), changes in lean body mass and in adipose mass, and adverse side - effects during human growth hormone (HGH) treatment of elderly men who had low IGF - I levels.