Three publications were excluded: one study examined only the association between duration of breastfeeding and fasting
plasma lipids at 17 y of age, and there was no formula - fed group for comparison (21); one examined the effect of nutritional supplementation in pregnant mothers, infants, and children on serum lipids in later life (18); and one was a review (22).
Not exact matches
Thus, distribution and mobility of specific
lipid species
at the
plasma membrane appears to precisely regulated by membrane - associated proteins.
Researchers
at the University of Chicago have found an unsuspected link between the immune system and high
plasma lipid levels (cholesterol and triglycerides in the blood) in mice.
«Both the neuronal and average human membrane models — arguably the most compositionally complex
plasma membrane
lipid models to date — showed non-ideal lateral
lipid mixing
at different length and time scales, demonstrating the inherent complexity of biological membranes.»
The metabolic analysis of the mice could be combined with clinical assessments, by performing biochemical analysis in blood,
plasma, urine and tissues (i.e,
lipid and cholesterol content, glycogen content...) and by performing autopsy of the animal
at the end of phenotyping study with several tissue collections (i.e, histology, mRNA anlaysis, protein analysis...).
Palmitoylation
at Cys - 416 is important for recruitment
at both
plasma membrane and
lipid rafts and association with G protein alpha subunits.
A part of the explanation might be the changes in
plasma membrane
lipid composition that accompany the secretion process and lead to changes in signaling properties of the receptors present
at the
plasma membrane (IGF - 1R, IR).
Aβ is believed to penetrate neuronal
plasma membranes, where it leads to
lipid peroxidation.10 It has also been implicated in deactivating a subunit of the pyruvate dehydrogenase complex, thereby inhibiting conversion of pyruvate to acetyl CoA and the eventual production of cellular energy as ATP.32 Another way Aβ affects glucose metabolism in the brain is that fragments of Aβ disrupt insulin signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant
at synapses, so if the integrity of the synapse itself has been compromised, the receptors won't function effectively.
Have a look
at this article from American Society for Clinical Nutrition (© 2008): http://ajcn.nutrition.org/content/87/5/1262.full «Effect of cinnamon and turmeric on urinary oxalate excretion,
plasma lipids, and
plasma glucose in healthy subjects»
«We looked
at about 4,600 metabolites and discovered that 10
lipids were significantly altered in the
plasma of cognitively normal older adults who would go on to develop the clinical symptoms of Alzheimer's disease.
The metabolic effects of specific starches on
plasma lipids, fasting and postprandial glucose and insulin profiles, and bowel function were assessed
at the end of each intervention.