Caroni's group focuses on the specific mechanisms that regulate plasticity in identified circuits as a function of experience, and the roles of
this plasticity in learning and memory.
Not exact matches
«
In animal studies, exercise has been shown to specifically affect the hippocampus, significantly increasing the growth of new neurons and cell survival, enhancing memory and learning, and increasing molecules that are involved in the plasticity of the brain,» Chaddock sai
In animal studies, exercise has been shown to specifically affect the hippocampus, significantly increasing the growth of new neurons
and cell survival, enhancing
memory and learning,
and increasing molecules that are involved
in the plasticity of the brain,» Chaddock sai
in the
plasticity of the brain,» Chaddock said.
They used a somewhat bizarre technique
in which two mice were sutured together
in such as way that they shared a circulatory system (known as parabiosis),
and found old mice joined to their youthful counterparts showed changes
in gene activity
in a brain region called the hippocampus as well as increased neural connections
and enhanced «synaptic
plasticity» — a mechanism believed to underlie
learning and memory in which the strength of neural connections change
in response to experience.
For instance, every time we
learn something, the new information is transformed into
memory through synaptic
plasticity, a process
in which synapses are strengthened
and become more responsive to different stimuli or environmental cues.
This opposing regulation of synaptic
plasticity supports optimal information processing
and storage
and highlights the unique role this region plays
in learning processes
and memory formation.
«My lab works on the neural bases of
learning and memory,» says Pozzo - Miller, «so we decided to test if LM22A - 4 was able to improve spatial discrimination deficits by enhancing synaptic
plasticity in the hippocampus, the brain region responsible for spatial
learning and memory.»
Maternal alcohol consumption prior to
and during pregnancy significantly affects cognitive functions
in offspring, which may be related to changes
in cyclin - dependent kinase 5 because it is associated with modulation of synaptic
plasticity and impaired
learning and memory.
NMDA receptors are key players
in plasticity, the cellular process of
learning and memory.
Since morphology changes of synapses underlie synaptic
plasticity and our
learning and memory, this will provide us with many new insights into mechanisms of how neurons store information
in their morphology, how it changes synaptic strength
and ultimately how it creates new
memory.
Specifically, he investigated the effects of autoantibodies against NMDA receptor
in the context of synaptic
plasticity and learning and memory,
and autoantibodies mGluR1,
in the context of synaptic remodeling
and cerebellar ataxia.
Researchers have discovered a new form of synaptic
plasticity, the changes to nerve cells
in the brain that underlie
learning and memory.
Egr proteins play a role
in the regulation of synaptic
plasticity,
learning and memory [76, 77]
and Egr3
in particular is very important for the processing of both short term
and long term hippocampal dependent
memory [78].
This
plasticity underlies functions like
learning and memory and is critical
in making us who we are as individuals.
RGS14 is a natural suppressor of both synaptic
plasticity in CA2 neurons
and hippocampal - based
learning and memory.
That means I need to find ways to increase BDNF more than
in someone with the normal gene
in order to preserve my cognitive function,
memory, and emotional regulation.8 Mu, J.S., et al. «Deprivation of Endogenous Brain - Derived Neurotrophic Factor Results in Impairment of Spatial Learning and Memory in Adult... continue 9Cirulli, F., et al. «Intrahippocampal Administration of BDNF in Adult Rats Affects Short - term Behavioral Plasticity in the Morris Water Maze and... co
memory,
and emotional regulation.8 Mu, J.S., et al. «Deprivation of Endogenous Brain - Derived Neurotrophic Factor Results
in Impairment of Spatial
Learning and Memory in Adult... continue 9Cirulli, F., et al. «Intrahippocampal Administration of BDNF in Adult Rats Affects Short - term Behavioral Plasticity in the Morris Water Maze and... co
Memory in Adult... continue 9Cirulli, F., et al. «Intrahippocampal Administration of BDNF
in Adult Rats Affects Short - term Behavioral
Plasticity in the Morris Water Maze
and... continue
Brain tissue is highly sensitive to alterations
in NAD + levels.67 A mouse study showed that supplementation with nicotinamide mononucleotide increased NAD + levels
in the brain, slowed cognitive decline
in mice with Alzheimer's,
and enhanced the
plasticity in neurons that underlies
learning and memory.67
Although a great deal of synaptic
plasticity occurs during early childhood as the brain is developing,
plasticity in the form of
learning and memory continues to shape our synapses throughout our lives.