Sentences with phrase «platelet reactivity»

Dr. Stone added: «Platelet reactivity on aspirin was unrelated to stent thrombosis, heart attack, or death, but may be related to bleeding.

At one year, researchers found that high platelet reactivity was significantly associated with stent thrombosis (1.3 percent vs. 0.5 percent) and heart attack (3.9 percent vs. 2.7 percent), but was also found to be protective against major bleeding (5.6 percent vs. 6.7 percent).

However, because high platelet reactivity is also associated with other patient risk factors and baseline characteristics, multivariable modeling was also performed; it showed no independent association between high platelet reactivity and mortality.

High platelet reactivity was also associated with one - year mortality (2.4 percent vs. 1.5 percent).

ADAPT - DES is the largest study ever to explore the overall treatment implications of platelet reactivity on patient outcomes after successful coronary drug - eluting stent implantation.

High platelet reactivity, defined as a PRU of greater than 208, was present in 42.7 percent of patients.

«Results from the ADAPT - DES registry definitely demonstrate that high platelet reactivity after implantation of drug - eluting stents is an independent predictor of one - year stent thrombosis and heart attack, but it is also protective against major bleeding, both of which impact mortality,» said lead investigator Gregg W. Stone, MD..

Patients who receive a drug - eluting stent (DES) and demonstrate high platelet reactivity on clopidogrel are more likely to have blood clots form on the stent and to suffer a heart attack; however, these patients are less likely to develop bleeding complications.

«Because of the counteracting effects of ischemia and bleeding, platelet reactivity was not an independent predictor of one - year mortality.

Not exact matches

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock - in mouse model of essential thrombocythemia.

Garlic also lowers blood pressure; inhibits platelet aggregation; promotes fibrinolysis; reduces plasma viscosity; prevents LDL oxidation; and exerts positive effects on endothelial function, vascular reactivity, and peripheral blood flow.