Sentences with phrase «play pivotal»

Subsets of CD4 + T lymphocytes play pivotal roles both in initiating the inflammatory process, by secreting pro-inflammatory cytokines, and by preventing inflammation, in part by secreting regulatory cytokines such as IL - 10 and TGFβ.

They play a pivotal role in regulating synaptic transmission, modulating excitotoxicity responsible for much of the neuronal damage caused by hypoxic insult in the brain [37], and are expressed in retinal photoreceptors, horizontal cells, and bipolar cells as well as the amacrine and ganglion cells of the inner retina [38 — 41].

The Genome Sequencing Centers will play a pivotal role in our systematic effort to assess the range of genomic changes associated with malignancy,» said Mark S. Guyer, Ph.D., director of NHGRI's Division of Extramural Research.

These findings suggest that prohibitin may play a pivotal role in EV1 infection of the nervous system in humans.

A balance between the activation of the inflammatory macrophages and suppression of the anti-inflammatory macrophages in the kidney may play a pivotal role in kidney stone formation.

In the future, NSF's LIGO will continue to play a pivotal role in widening the window on the universe and expanding the boundaries of science.

«Cd14 seems to play a pivotal role in the maintenance of barrier integrity.

New research shows a network of immune cells helps the appendix to play a pivotal role in maintaining the health of the digestive system, supporting the theory that the appendix isn't a vestigial — or redundant — organ.

The gradual erosion of telomeres — the strands of DNA that cap our chromosomes and wear away with each cell division — may play a pivotal role in heart disease.

Professor Gabrielle Belz has shown that a network of immune cells helps the appendix play a pivotal role in maintaining digestive health.

Submicron atmospheric aerosols, although they are not so visible, play a pivotal role in the climate system.

Normal microorganisms in the intestines appear to play a pivotal role in how the HIV virus foils a successful attack from the body's immune system, according to new research from Duke Medicine.

The authors argue that SFM can play a pivotal role in promoting desired «societal, environmental and economic outcomes».

However, regulatory affairs professionals play a pivotal role in facilitating the progression of new health products and technology through the product life cycle (see figure).

Scientists from Trinity College Dublin have made a significant breakthrough in understanding the regulation of immune cells that play a pivotal role in allergic diseases such as asthma and eczema.

In cancers, both gene mutations and aberrant regulation of genes (promoter inhibition by methylation of DNA) are known to play pivotal roles regulating cancer growth.

«Understanding biomechanics can play a pivotal role in recreating motion in dinosaurs or any other moving organism.»

Transcription factors play a pivotal role in many illnesses, including cancer as well as many hereditary diseases.

This large - scale analysis allowed us to identify exactly which genes play a pivotal role in a plant's defense mechanism against drought.

These studies suggest that children, particularly teens, should play a pivotal role in the design and development of mobile apps designed to keep them safe online.

So surround yourself with people who galvanize you — they could play a pivotal role in your own ingenuity.

Sea otters off the Alaskan coast play a pivotal role in marine ecosystems: By dining on sea urchins, the animals help preserve kelp forests that feed a range of species, from barnacles to bald eagles.

The hunt is on to find new particles and deeper, broader symmetries from which they stem, a process in which Noether's theorem continues to play a pivotal role.

These results suggest that ESR1 may play a pivotal role in modulating gene - regulatory networks after learning.

Humans will play a pivotal role in formulating the intricate complex of laws that will govern corporate behavior.

As the interface between hippocampus and neocortex, the entorhinal cortex is likely to play a pivotal role in memory.

As well as medical imaging and airport security scanning, masers could play a pivotal role in improving sensors to remotely detect bombs, new technology for quantum computers, and might even improve space communication methods to potentially find life on other planets.

Carl Heastie, the new Assembly speaker who would go on to play a pivotal role in budget negotiations, received a standing ovation when he told the member - lobbyists, «To me, it's unfair to blame teachers when some of our children have problems at home before they even walk into the schools.»

Along with the star - power that Clinton brings to his former home state, he could also play a pivotal role in bringing out African American voters, a key constituency group that Lincoln will need to beat Halter.

Quinn's Lower East Side Democratic Club will play a pivotal role in the County Committee vote.

If a working - class party is to play the pivotal role necessary to winning universal health care, there must be a wider assessment of current political weaknesses on the left, and concrete discussions of how to leverage the potential strength of both unionized and nonunionized workers to win real health care reform.

Production Manager, director, lighting engineer, sound engineer, stars and other few ones who play pivotal roles, have their privacy in hotels, the rest sleep in receptions without a room.

Everyday, mothers play the pivotal role of raising and moulding their children.

It was a twist - filled week for political wags who are closely watching the race for the 60th State Senate, a seat that could play a pivotal role in shaping Albany's balance of power.

With Cuomo already accumulating substantial institutional support, such as Sen. Kirsten Gillibrand and the major health care workers union 1199SEIU, the Working Families Party could play a pivotal role in Nixon's candidacy.

That some of those who would play a pivotal role in passing the laws of our land would do so by virtue of a title they inherited from their parents or from the patronage of another politician?

New York Republican Committee Chairman Ed Cox said because the campaigns in both the Republican and Democratic races are so close, New York could play a pivotal role.

«Their support will play a pivotal role in this election and I'm proud to be their candidate.»

In a statement announcing the Gingrich and Santorum appearances, Chairman Ed Cox said the state will play a pivotal role in deciding who the nominee might be.

Everyday, Mothers play the pivotal role of raising moulding and uniting families and communities, to build a bright future for their children to become responsible leaders.

«The Legislature, assemblymembers, senators on both sides, both political stripes, they have very good working knowledge of what goes on in their district,» said Republican Senate Majority Leader John Flanagan, «and I think we should play a pivotal and critical role in making those decisions.»

The DCCC's support could play a pivotal role in the primary.

In the past 53 years, the Conservative Party has played many pivotal rolls in electing officials from Supreme Court Justices to Town Justices, County Executives to Village Board Members, Mayors and City Council Members to Ward Leaders, and will continue to play a pivotal role in the process of electing those who are committed to conservative values.

«Our forests are a much loved part of our national natural heritage, and will play a pivotal role in the green economy and our low carbon future,» shadow environment secretary Mary Creagh said.

«We stand in solidarity with horse carriage workers who play a pivotal role in generating millions of dollars in revenue as one of the top three tourist attraction [s] in the city,» wrote Lipton, a close ally of de Blasio.

The race for the 8th district seat in the Erie County Legislature between two - term incumbent Legislator Ted Morton, a Republican, and John Bruso, a Democratic newcomer, could play a pivotal role in determining which party controls the 11 - seat body.

The new advanced medical centre is expected to help Ghana to further play a pivotal role in health research across the West African sub region.

This is an exciting and challenging time for the Liberal Democrats and we expect the Social Liberal Forum to play a pivotal role during this period.

ALBANY — While Democrats and Republicans continue to be the dominant party designations in New York, third parties also play a pivotal role in the state's political structure.

This refers to rare earth metals or rare - earth elements (REMs), a set of 17 naturally occurring non-toxic materials, which play a pivotal role for emerging technologies and which are predominantly produced and exported from China.Estimations of China «s hold on the REMs market are as high as 97 % of the world production.