Sentences with phrase «plays key functions»

However, given that APOE plays key functions in peripheral immune cells that are very similar to microglia (eg, macrophages), it is surprising that the role of APOE in microglia is practically unexplored and remains largely unknown.

Technology will play a key function in facilitating Token Sale compliance and harmonising this rising business.

Synopsis: We're talking about handoffs and sales development a lot in this eBook, because those play a key function in this strategy.

● Play a key function in researching, resolving and applying applicable credits while maintaining positive business relationships with vendors.

Not exact matches

Selenium support thyroid function, cognitive function and immune system, and plays a key role in metabolism.

A happy tummy is so important as digestive health plays a key role in every aspect of the body's functions.

«Water plays a vital role in helping the body perform many essential functions, and making smart hydration choices is a key first step to maintaining a healthy lifestyle,» said Sarah Ladden, a registered dietitian and Director, Nutrition, Health & Wellness at Nestlé Waters North America.

Take Steven Gerrard for instance: he, too, doesn't have the physical power of a Yaya Toure or Nemanja Matic but, playing at No. 4 for the Scousers, the former England skipper still plays a key role in the functioning of Liverpool machine.

«This process may therefore play a key role in neural development and central nervous system function in adults, as well as in chronic brain disorders and various acute brain injuries.»

Myelin plays a key role in the health and function not only of neurons but the brain and the rest of the nervous system, too.

Zinc plays a role in many key body functions, including immune system response, so it's important to get enough of it, which vegans can do by eating nuts, legumes, miso and other soy products, pumpkin and sunflower seeds, tahini, wheat germ, and whole - grain breads and cereals.

Brainstem abnormalities that involve the medullary serotonergic (5 - hydroxytryptamine [5 - HT]-RRB- system in up to 70 % of infants who die from SIDS are the most robust and specific neuropathologic findings associated with SIDS and have been confirmed in several independent data sets and laboratories.37, — , 40 This area of the brainstem plays a key role in coordinating many respiratory, arousal, and autonomic functions and, when dysfunctional, might prevent normal protective responses to stressors that commonly occur during sleep.

It should go without saying that, by shifting the attention to the design and implementation of the «78 regime as a key latent root cause of the current political crisis in Spain, I am not denying the important conciliatory and transitory functions the constitution played at the time.

«This is problematic because visual periphery — which plays a critical role in mobility and other key visual functions — is often less affected by visual impairments.»

They also identified genomic hotspots that seem to play a key role in adaptation and survival, with many having an unknown function.

These play a key role in controlling gene expression and, thereby help regulate the cell's development, growth and function.

«While it has been established that prostaglandins play a key role in the way many species reproduce, Dr. Miller's research has uncovered a novel effect that prostaglandins may have on sperm function,» said Richard Okita, Ph.D., of the National Institute of Health's National Institute of General Medical Sciences, which partially funded the research.

Cannabinoid receptors are part of a large class of receptors known as G protein - coupled receptors (GPCR), which account for about 40 percent of all prescription pharmaceuticals on the market, and play key roles in many physiological functions.

«Because many broadly expressed genes that play key roles in essential cellular functions are under the control of cell - specific enhancers, the ability to affect enhancer function by knocking down eRNAs could potentially provide a new strategy for altering gene expression in vivo in a cell - specific manner,» said Glass, noting that in his research, anti-sense oligonucleotides were developed in conjunction with Isis Pharmaceuticals, which suppressed enhancer activity and reduced expression in nearby genes.

For example, work by Whitfield and his colleagues suggests that social support might play a key role in preserving cognitive functioning among African - Americans.

Hancock's group showed that inhibiting the enzyme p300 can affect the functions of another protein, Foxp3, which plays a key role in controlling the biology of Tregs.

Dr. Espen Spangenburg, associate professor of kinesiology, and his laboratory team are the first to identify that the BRCA1 protein is expressed in the skeletal muscle of both mice and humans, and that it plays a key role in fat storage, insulin response and mitochondrial function in skeletal muscle cells.

T cells, white blood cells that are a key part of the immune system, may also play an important role in cognitive function.

Astrocytes could thus play a key role in the early stages of the disease and changes in the function of these cells could lead to neurodegeneration.

«Proteins in the cell envelope play key roles in cell function and bacterial physiology,» Sikora said.

Subjects would indicate to researchers when they were planning the movement, so the researchers could see what part of the cerebral cortex — the outermost region of the brain, which plays a key role in functions from movement to attention to learning — responded if a button - push was or was not executed.

«We found that a specific cellular pathway, AMPK - PGC1a, likely plays a key role to reduce mitochondrial function and content, which means that new therapeutic approaches that restore and increase mitochondrial function and content could ameliorate or perhaps even arrest chronic kidney disease.»

In plants, zinc plays a key role in essential functions such as carbohydrate metabolism, photosynthesis, and sugar and starch synthesis.

«The real story here is that we probably need sea otters more than they need us, as they play key roles in the functioning and resiliency of kelp forest and estuarine ecosystems that provide a wide range of services to human societies,» said Dr. M Tim Tinker, a research scientist with the U.S. Geological Survey who is presenting an overview of the latest research on southern sea otters and is coauthor of several other new studies presented at the conference.

Many of the insertion sites were located within genes that play key roles in normal brain function.

The FUS protein normally plays a key role in the healthy functioning of neurons, which transmit nerve signals in the brain and spinal cord.

By demonstrating that key individual species within the ecosystem can play a disproportionally large role in carbon cycling, this study helps bring us a step closer to understanding the function these microbes play in larger questions of climate warming and increased acidity in the ocean.

O - GlcNAc not only plays a key role in signaling, in transcription and in cytoskeletal functions, but it also underlies glucose toxicity in diabetes, is important in neurodegenerative diseases and is important in cancer etiology.

Sugars, and the lectins that attach to them, seem to play a key role in how cells «talk» to one another, call for help, and perform other functions.

In new research being presented at the meeting, scientists suggest that the blood - brain barrier in the brainstem — the primitive brain area responsible for many of the body's basic functions, such as breathing, heart rate, sleeping, and eating — could play a key role salt - induced baroreflexin regulating blood pressure.

This led the researchers to conclude that the abnormal functioning of the astroglial cells plays a key role in the occurrence of Down syndrome.

March 6, 2013 One region, two functions: Brain cells» multitasking may be a key to understanding overall brain function A region of the brain known to play a key role in visual and spatial processing has a parallel function: sorting visual information into categories, according to a new study by researchers at the University of Chicago.

She chose the dynamics and function of the tumor suppressor protein p53, which plays a key role in cancer and is widely studied.

Scientists from the UNC School of Medicine have developed a new tool for studying a key process in cells called G - protein signaling, which plays a central role in the normal functioning of cells and can go awry to cause severe disease, including cancers.

Chromatin structure and function as well as epigenetic processes play key roles in regulating pluripotency and early differentiation events.

In addition, autophagy inhibition is starting to be considered in clinical trials and autophagy plays a key role in the regulation of mitochondrial function.

Cyclic proteins that assemble from multiple identical subunits (homo - oligomers) play key roles in many biological processes, including cell signaling and enzymatic catalysis and protein function.

While much remains to be learned about the details of the processes involved in that decline, it now looks as though chromatin, so important to so many cellular functions, plays a key role.

Different species within an ecosystem may play vital roles in ensuring that specific key functions are performed - for example, insects pollinating flowers or earthworms decomposing organic matter.

They do, however, play a key role in helping to boost the anti-tumor immune response by: (1) expanding the number and improving the function of existing CTLs that are specific to the same tumor antigen; and (2) providing help to other immune cells, including B lymphocytes that are precursors to antibodies and natural killer (NK) cells that are also important in the overall anti-tumor immune response.

But magnesium is incredibly important for many of the body's functions — it plays a key role in your immune system, nerves, and muscles, and helps keep your heart and bones strong.

Potassium is a mineral that plays a key role in cell function, including regulating fluid balance.

Selenium is essential for the proper functioning of the thyroid gland and thyroid hormone production and is a key component of the enzyme which helps convert thyroxine to triiodothyronine, which plays a key role in keeping the metabolism rate elevated.

These minerals play a key role in your health and regulate diverse biochemical reactions, from nerve and muscle function and protein synthesis.

However, recent findings suggest that lutein may also play a key role in preserving brain function, slowing down cognitive decline that starts as early as mid-adulthood.