Sentences with phrase «pleuropneumoniae challenge model»

But we wanted to challenge the model.

As you read through this review, you will learn some of the challenges this model has faced in the past but seems to have overcome recently.

The so - called «human challenge model» has a long and checkered past that began with 18th century experiments by smallpox vaccine developer Edward Jenner and later fell under intense scrutiny when they were conducted by Nazi doctors, military researchers, and academic scientists working with prisoners.

Dr. Whitehead is currently developing a human challenge model using a modified dengue serotype - 3 virus.

But new findings published recently in Current Biology challenge this model, finding that the majority of toxin genes for parasitoid wasp species are instead «moonlighting» from other physiological roles.

The results of the study challenge the model that comparing mean gene expression in adjacent normal and cancer tissues is the best approach to identifying cancer - associated genes.

He explained that his research regarding human altruism ultimately challenges a model of evolution that requires merciless victors.

«We heard, «You can't treat dengue so you can't do a human challenge model,»» Durbin says.

The findings also challenge models of the planet's interior, pointing to a core that is not solid like Earth's, but is instead «fuzzy» and dilutely mingled with an overlying metallic hydrogen layer.

«Seattle BioMed's Malaria Clinical Trials Center is one of only four centers in the world approved to safely and effectively test new malaria treatments and vaccines in humans by the malaria human challenge model.

The assay will be validated against clinical outcomes in human vaccine studies (correlates of protection such as neutralising antibodies or vaccine - induced protection in human challenge models, or exploratory correlates such as multifunctional Th1 cells).

«We see a Zika challenge model as really beneficial for not only vaccine development,» Durbin said, «but also to learn more about Zika itself.»

We exposed BALB / c mice to mutant strains and the wild - type strain in an aerosol challenge model using lethal B. mallei doses.

In a next step the efficacy of the vaccine will be tested in a non-human primate challenge model.

Insectary Originally developed by WRAIR, the human malaria challenge model enables in - house testing of prophylactics, therapeutics and vaccines.

The Virology Group at Cardiff University seek to recruit a Research Associate to work on a Wellcome Trust Collaborative Grant entitled: «Exploiting a human challenge model to understand the pathogenesis of cytomegalovirus».

Since we observed robust inhibition of NFκB in the presence of RIPK2 inhibitor 1 and a > 70 % recovery of animals from DSS - induced inflammation injury (Figs. 4 and 6B), we proceeded to explore the ability to resolve lung inflammation using the ovalbumin challenge model (Kumar et al., 2008).

Moving the Needle provides quarterly updates from PATH's Center for Vaccine Innovation and Access (CVIA) on our vaccine development efforts, as well as related supporting work, such as developing human challenge models, building capacity of developing - country vaccine manufacturers, and evaluating new adjuvants and other novel vaccine technologies.

However, there is emerging evidence that challenges these models and suggests that functional connectivity between brain regions can be stronger in ASD (Uddin et al., 2013).

These computationally challenging models were calculated on computers at the National Energy Research Scientific Computing Center at Lawrence Berkeley National Laboratory in Berkeley, Calif..

Efficacy studies depend on the availability of the challenge model and can be performed in biosafety containment up to BSL3.

With tweaks, some of the challenged models can survive the latest test by the star merger, Zumalacárregui said, though they «lose some of their simplicity» in the process.

As an additional example, established anticonvulsant effects of ketogenic diets in humans and rats are countered by only mixed success in mice in various seizure models.54, 55, 56 Therefore, mice might be a challenging model for exploring the relationship between a ketogenic diet and pain and inflammation.

A group of leaders recently gathered to challenge this model at the Askwith Education Forum, «Longer Days in Better Schools: The Expanded Learning Model.»

The set includes three learning mats, a challenge mat, dual lock tape, and all of the LEGO elements required to build the challenge models.

With a release date set for the spring of 2015, the 2016 Mercedes - AMG GT will roar its way onto the Loeber Motors ready to challenge models like the Aston Martin V8 and Audi R8 V8.

You'll also unlock game situation types of challenges modeled on NBA games from the prior season.

As a modeler working among observationalists from a variety of disciplines, Jinlun has never been short of tire - kickers who probe, push, and challenge his model from all sorts of different angles and identify warts and beauty spots.

So, getting better measurements would challenge models to be more physical.

Part of the story here is that it is this very sort of very careful work done by John Kennedy and Phil Jones and other colleagues working on these datasets that has allowed us to start challenging the models and our understanding in such a detailed way — in some ways it is quite remarkable that the observational data is now good enough to identify this level of detail in how the climate varies and changes.

They can't challenge the models unless they deconstruct the code.

Challenging the models is pure obfuscation and time wasting.

Steve, I agree that we need to do a better job of challenging the models with data and interpreting the results.

Anything that challenges the model challenges the result; any test that the model passes lends credibility to the result.

For what it's worth, I have talked to model developers at length about this and I've been involved in improving the way that observations are used to challenge models.

In her postdoc, soon to start at the British Antarctic Survey, Kaitlin will be working on similarly challenging modeling, this time for the Filchner - Ronne ice shelf.

While it's true that it is risky to «bite the hand that feeds,» these cities are entirely justified in challenging a model that's clearly not working for them.

But that change would challenge a model that today delivers high profits.

But Gibbon said the company kept parts of its popular but challenged models online — which may have also contributed to its eventual shut - down.

As, android Eight.zero is Google's subsequent most challenging model to its old OS acknowledged as Marshmallow.

The challenge model: Working with strengths in children of substance - abusing parents.

Not exact matches

If you've believed the Or model of introversion and extroversion your whole life and resist the And model, try this challenge: try believing the And model for a week or a month.

Though it suffered through a challenging 2016, the company bounced back by revamping its sales model and expanding in India, where it rivals Samsung Electronics Co. (samsung - ct) as the biggest vendor.

Adding employees and shifts and paying more overtime to workers will raise costs for Tesla, another challenge to the Model 3 margins.

The challenge is that they tend to live on a business model where they get big enough to get noticed by someone big, who then buys them.

With challenges like securing small business financing, creating a workable business model for your novel idea, and carrying out your project in real life, entrepreneurs are usually the -LSB-...]

Series A will require continued discipline, and Series B and C will remain challenging for companies without reasonable scale and proven economic models.

Davis admits Home Hardware's quasi-co-operative business model presents some challenges: The firm has neither the deep pockets of its publicly traded rivals, nor the top - down control of a franchise operation.

Instead they challenged members of the old guard to defend what they call dated business models.

The technical challenge they had embarked on was indeed daunting, requiring models for turning speech, with all its nuances and inflections, into neatly labeled data that can be fed into machine - learning algorithms, which would then try to extract behavioral patterns from it.