Sentences with phrase «pluripotency without»
Human ES and iPS cells grow as monolayers in a completely defined and xeno - free cell culture environment that enables self - renewal and pluripotency without the use of ROCK inhibitors.
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What's more, he says, the team «took advantage of the other property» of the system, which was that it could be mobilized via an enzyme, transposase, to effect the «seamless removal» of the foreign DNA without disrupting the newly gained pluripotency.
By identifying these factors, it should be possible to induce pluripotency in somatic cells without using embryos or oocytes.
The activated AHR / NuRD complex altered the expression of differentiation - specific genes that control the first two developmental decisions without affecting the pluripotency program.