Sentences with phrase «pluripotent cell source»
In the several years since those first reports, new advances in the derivation of hiPSCs from various tissue sources (including those from human patients) and using diverse reprogramming techniques, and in their use as a pluripotent cell source in the induced differentiation of a wide array of somatic cell types, have appeared with almost startling rapidity.
https://stemcellres.biomedcentral.com/ Not exact matches
According to the National Institutes of Health's definition, however, pluripotent embryonic stem cells are «the embryonic source of all cells of the body.»
But on the same day, he also revoked the very kind of policy that promoted the «purple» governance he claimed to want, e.g., Bush's directive that funding priority be given to funding non embryonic — and hence, societally uniting sources of pluripotent stem cells — even though they had already been discovered in the induced pluripotent stem cell breakthrough.
Although liver cells created from induced pluripotent stem cells reflect the defects of their source, they may offer a new tool to study inherited disorders
Whatever the source of pluripotent cells, Thomson says, researchers face the same scientific challenges — namely, understanding how to convert them into key tissues such as the beta islet cells that are impaired in diabetics, and then how to introduce them safely and effectively into humans.
«Induced pluripotent stem cells have tremendous potential as a source for personalized cellular therapeutics for organ repair,» said Joseph Wu, MD, PhD, director of the Stanford Cardiovascular Institute.
Derivation of pluripotent stem cells, either of embryonic origin or following genetic reprogramming, has opened the path for an alternative source for epidermal cell therapy as these cells are both immortal and pluripotent, theoretically capable of providing any requested number of cells of any desired phenotype.
Unlimited source of keratinocytes and melanocytes derived from pluripotent stem cell for epidermis cell therapy
Human pluripotent stem cells from two sources today, one physiological embryonic stem cells «ES» from the embryo, and the other experimental cells «iPS» induced pluripotency by reprogramming genetic somatic cells.
A new study describes an improved protocol for the efficient differentiation of endothelial cells from pluripotent stem cell sources and highlights the importance of the MAPK and PI3K signaling pathways
This is posited to create a safer and more robust source of induced pluripotent stem cells (iPSCs) from patient samples for subsequent differentiation towards transplantable RGCs.
Embryonic stem cells (ESCs) represent a source for the large numbers of modified EPCs required to therapeutically inhibit tumorigenesis [3], although patient - specific induced pluripotent stem cells (iPSCs) represent a more attractive option.
Researchers take the first steps towards creating a clinically - relevant source of platelets from human induced pluripotent stem cells.
Our platform includes two distinct approaches to create these vaccines: AST - VAC1, an autologous (patient - specific) vaccine based on cells sourced from the patient, and AST - VAC2, an allogeneic (non-patient specific) vaccine manufactured from our proprietary pluripotent stem cell platform.
Scientists create organoids from a variety of cellular sources, including induced pluripotent stem cells.
A series of alternative sources of human pluripotent stem cells, perhaps most notably so - called induced pluripotent stem (or iPS) cells, have been increasingly proving their utility.
However, the further development this type of therapy requires a reliable source for the large amounts of homogenous functional patient - specific NK cells needed and this has led to the generation of NK cells from human induced pluripotent stem cells (iPSCs)[3].
In sum, human NSCs represent an invaluable source of cells to investigate human iPS induction, and also represent a potential source of cells for deriving patient - specific pluripotent stem cells for modeling human disease.
CReM's research using induced pluripotent stem cells (iPSCs), which self - renew indefinitely as undifferentiated cells that become specific adult cell types, has helped create an inexhaustible source of disease - or patient - specific stem cells.
Reprogramming by nuclear transfer might provide an important source of pluripotent stem cells from human beings, including patients needing cell therapies.