Sentences with phrase «points during the replication»
To monitor such changes, they isolated DNA at several time points during the replication and repair process, and quantified the bound proteins using mass spectrometry based proteomics.
https://www.sciencedaily.com/ Not exact matches
This is because during replication, DNA polymerase can only synthesize DNA in a 5 «to 3 «direction and can only do so by adding polynucleotides to an RNA primer that has already been placed at various points along the length of the DNA.
Moreover, given that point mutations are acquired through DNA copy - errors (and / or failure of DNA damage repair mechanisms) during replication, preferentially within the paternal germline, a detailed knowledge of these basic biological processes is key to understanding the patterns of nucleotide substitutions.