Pathways and mechanisms of protein trafficking in
polarized epithelia; Wilson and Menkes Diseases; copper ATPases
Of the many types of
polarized epithelia, we have focused on liver hepatocytes, which exhibit a complex polygonal polarity, and simple columnar cells of the intestine.
Septin GTPases spatially guide microtubule organization and plus end dynamics in
polarizing epithelia.
Not exact matches
In the Intestine Chip, the
epithelium forms villi - like projections lined by
polarized epithelial cells that undergo multi-lineage differentiation similar to that of intestinal organoids, however, these cells expose their apical surfaces to an open lumen and interface with endothelium.