Sentences with phrase «polyketide synthase»

Hendrickson, L. Davis, C. R. Roach, C. Nguyen, D. K. Aldrich, T. McAda, P. C. and Reeves, C. D. Lovastatin biosynthesis in Aspergillus terreus: characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene.

Kennedy, J. Auclair, K. Kendrew, S. G. Park, C. Vederas, J. C. and Hutchinson, C. R. Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis.

In 2014, in collaboration with Life Sciences Institute colleagues Janet Smith and David Sherman, Skiniotis published two Nature papers that describe his use of cryo - EM to reveal the structure of a modular polyketide synthase (PKS).

Defense: «Effects of canopy cover and pH on polyketide synthase gene transcription in Cladonie stygia and the polyketides produced in natural conditions.»

They first introduced three genes from a soil bacterium called Saccharopolyspora erythraea, which together produce an enzyme called a polyketide synthase, which produces one particular polyketide.

The bacteria make polyketides with the assistance of a family of enzymes called polyketide synthases (PKSs).

But polyketide synthases don't work without a co-factor called phosphopantetheine, so the researchers also introduced a gene from the soil bacterium Bacillus subtilis that encodes the enzyme that attaches phosphopantetheine to the polyketide synthase.

Despite the substantial differences between these two classes of natural products, each is synthesized biologically under the control of exceptionally large, multifunctional proteins termed polyketide synthases (PKSs) and non-ribosomal peptide synthetases (NRPSs) that contain repeated, coordinated groups of active sites called modules, in which each module is responsible for catalysis of one complete cycle of polyketide or polypeptide chain elongation and associated functional group modifications.

Taek Soon Lee earned a B.S. in Chemistry at Seoul National University (Korea) and a Ph.D. in Chemistry at Stanford University in 2006 studying type II aromatic polyketide synthases with Professor Chaitan Khosla.

Amoroso, Jon William (2014) Reactive Probes for Manipulating Polyketide Synthases, and Photoreactive Probes for Strained Alkyne Kilauea; Mount Etna; Mount Yasur; Mount Nyiragongo and Nyamuragira; Piton de la Fournaise; Erta Ale

Amoroso, Jon William (2014) Reactive Probes for Manipulating Polyketide Synthases, and Photoreactive Probes for Strained Alkyne,, May, 2004.