Maitz MF, Freudenberg U, Tsurkan MV, Fischer M, Beyrich T, Werner C. Bio-responisve
polymer hydrogels homeostatically regulate blood coagulation Nature Communications, Doi: 10.1038 / ncomms3168 (2013)
Not exact matches
The use of
hydrogels dressings is a concept stolen from disciplines such as geriatrics, where patients suffer bed wounds and these water - based
polymer matrix dressings are applied to maintain moisture, inhibit scab or crust formation, reduce pain, and enhance epithelial migration for wound repair.
What makes them absorbent is the
hydrogels, or
polymers, which can absorb up to 100 times their weight.
In related work for drug - release systems built from biocompatible and biodegradable
polymers, IMRE has developed injectable
hydrogels to deliver drugs.
He and his colleagues began by designing a
hydrogel, a network of
polymers that absorbs large amounts of water.
Her team developed an earlier bacterial
hydrogel made with the algae - produced
polymer alginate, but did not cast it into functional products.
The team's
hydrogel has two sugar - based
polymer ingredients — hyaluronic acid and the seaweed extract carrageenan — to provide structure and to nourish the bacteria.
The principle component of the new panel,
hydrogel — a
polymer network filled with water — is safe to use in and on the human body, having already found use in applications ranging from drug delivery to creating scaffolds for tissue engineering and wound healing.
Another treatment option being explored is injectable
hydrogels, substances that are composed of water and a
polymer.
It can handle a multitude of stiff and elastic materials including
hydrogels, silver nanoparticle - based conductive inks, liquid crystal elastomers and shape memory
polymers, or SMPs.
For instance, his group developed a
hydrogel that forms additional crosslinks between the
polymer chains after injection.
Furthermore, bacteria, unlike mammalian cells, are compatible with most
hydrogels — gel - like materials that are made from a mix of mostly water and a bit of
polymer.
Stroock created the same tension in his transpiring system by using a high - tech fabric of cross-linked
polymers called a
hydrogel.
The research, focused on developing thermosensitive nano -
hydrogels which, through a polymerization technique, mixes substances with different chemical and physical characteristics, achieving a chemical reaction and forming a set of small spheres called
polymers.
Standard tissue engineering involves seeding types of cells, such as those that form ear cartilage, onto a scaffold of a
polymer material called a
hydrogel.
The researchers first prepared the anesthetic
hydrogels with a
polymer to help it stick to the lining of the mouth.
By introducing different degradable groups to the
polymer chains, the researchers were able to alter how long it took for the
hydrogels to degrade.
To form a
hydrogel, the researchers mixed these particles with a
polymer — in this case, cellulose.
This is a representation of
hydrogel polymers (straight lines) trapping stem cells (light - colored figures) and water (blue).
Benoit and her team were able to manipulate the time it took for
hydrogels to dissolve by modifying groups of atoms — called degradable groups — within the
polymer molecules.
To make the nanosponge -
hydrogel, the team mixed nanosponges, which are nanoparticles that absorb dangerous toxins produced by MRSA, E. coli and other antibiotic - resistant bacteria, into a
hydrogel, which is a gel made of water and
polymers.
«The resulting
hydrogel composed of physically self - assembled CarHC
polymers exhibited a rapid gel - sol transition on light exposure, which enabled the facile release / recovery of 3T3 fibroblasts and human mesenchymal stem cells (hMSCs) from 3D cultures while maintaining their viability.»
Traditional
hydrogels made up of either synthetic
polymers or natural biomolecules often serve as passive scaffolds for molecular or cellular species, which render these materials unable to fully recapitulate the dynamic signaling involved in biological processes, such as cell / tissue development.
This, says NIST materials scientist Carl Simon, has led to a large and rapidly expanding collection of possible 3D scaffolds, ranging from relatively simple gels made of collagen, the body's natural structural matrix, to structured or unstructured arrangements of
polymer fibers,
hydrogels and many more.
Hydrogels are
polymers that absorb moisture.
Gregory explains, «Using a hand - held laser, we were able to selectively and quickly shrink the
hydrogel (a hydrophilic
polymer gel comprised mostly of water) in desired areas.
Hydrogels are soft networks of
polymers with high water content, like jello.
Specific duties will include basic and advanced
polymer chemistry protocols, cell culture and expansion,
hydrogel biomaterial characterization, physical characterization of biomaterials, assembly of 3D constructs using biofabrication and bioprinting techniques, collection and organization of data, and assisting in the preparation of reports and manuscripts.
Two microRNAs with synergistic effects, one that suppresses tumor growth and another than inhibits tumor promotion, are combined in an RNA triple helix, complexed with a dendrimer to form nanoparticles, which are incorporated with a
polymer to form a
hydrogel that inhibits tumor growth when applied to the tumor.
Hydrogels and macroporous sponges based on
polymers are two examples of such materials and they have structures that encourage new tissue to grow.
«When this
polymer forms a
hydrogel, it will entrap the cells.
Hydrogel Templates for the Fabrication of Homogeneous
Polymer Microparticles.
Osteogenic induction of human bone marrow - derived mesenchymal progenitor cells in novel synthetic
polymer -
hydrogel matrices.
The researchers made the
hydrogels by mixing together microbeads of one type of
hydrogel that degrades very rapidly in a solution of another
polymer that degrades much more slowly.
Many of these materials are not new:
hydrogels, liquid - crystal elastomers, and even more conventional
polymers like polystyrene.
The new
hydrogel type can be seen in these electron microscopy images, which show the nanogel and
polymer structure at different magnifications (Image: MIT)
The device is composed of a
polymer base containing an array of imprinted or shaped «
hydrogels,» a mesh of molecules that can absorb water like a sponge.
This
hydrogel material is made with plant cellulose - an organic
polymer that makes up plant cell walls and keeps our masks pieced together - and soothing aloe juice.
Tags for this Online Resume: biomaterials, biopolymers, cell culture, stem cells, rheology, materials science, scientist, associate scientist, biomedical engineer,
hydrogels,
polymers
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite
hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques,
polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable
hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed
hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured
hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of
hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-
polymer using various
polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-
polymer Loaded antibiotic on grafted co-
polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign