Sentences with phrase «polymer scaffold»

«Our experimental model represents a promising technique to culture human liver cells and prepare them for transplantation on a biodegradable polymer scaffold into the peritoneal cavity,» concluded Dr. Pollok.
Macchiarini produced artificial windpipes by taking a polymer scaffold and «seeding» it with stem cells from the recipient, which he claimed colonized the scaffold and eventually grew into a living organ.
The tracheae were made of a polymer scaffold that was seeded with the patients» own stem cells.
Ozone treatment caused no changes in the PLGA and no loss of function, with cells still able to grow on the polymer scaffold, as they would in treatments.
Patient Andemariam Beyene died after the implant, a polymer scaffold seeded with his own stem cells, failed.
One would culture thin sheets of meat, seeded by cells from a living animal, on a reusable polymer scaffold; the other would grow meat on small edible beads that stretch with changes in temperature.
These tiny polymer scaffolds contain channels that are about 100 micrometres wide, about the same diameter as a human hair.
The polymer scaffolding itself simply biodegrades after several months.
He then seeded the cells on a polymer scaffolding, infused them with apatite (a mineral component of bone), and injected the mix into small holes he had drilled into the animals» skulls.
Tissue engineered tri-leaflet heart valve — preliminary fabrication of biodegradable polymer scaffolds.
Snapshot: Polymer scaffolds for tissue engineering.
Analysis of 3D bone ingrowth into polymer scaffolds via micro-computed tomography imaging.
Human liver cells were distributed across a three - dimensional porous structure of the polymer scaffolding.
Stephan realized that he could load anti-tumor T cells — immune cells specially engineered to recognize and destroy cancers — into dissolving polymer scaffolds and place them directly at tumor sites.

Not exact matches

The researchers in Bayreuth also found out that the elongated polymers possess a scaffold formed by its side chains, which stabilizes the elongated structure.
In nature, the resilient lignin polymer helps provide the scaffolding for plants, reinforcing slender cellulosic fibers — the primary raw ingredient of cellulosic ethanol — and serving as a protective barrier against disease and predators.
The principle component of the new panel, hydrogel — a polymer network filled with water — is safe to use in and on the human body, having already found use in applications ranging from drug delivery to creating scaffolds for tissue engineering and wound healing.
Tissue engineers hope to one day grow organs on polymer foam scaffoldings, much as topiary gardeners grow animal - shaped bushes on elaborate trellises.
In a study last year, Lancaster, now at the MRC Laboratory of Molecular Biology in Cambridge, England, and Knoblich got more consistent results by adding polymer filaments as scaffolding to guide the organization of the minibrain models.
These tiny polymer microparticles could one day serve as scaffolding for tissues to rebuild themselves.
The scaffold is made from a polymer sheet and zapped with a laser to form a honeycomb structure of individual pores, each shaped like a concertina roughly 500 micrometres long.
Standard tissue engineering involves seeding types of cells, such as those that form ear cartilage, onto a scaffold of a polymer material called a hydrogel.
Traditional hydrogels made up of either synthetic polymers or natural biomolecules often serve as passive scaffolds for molecular or cellular species, which render these materials unable to fully recapitulate the dynamic signaling involved in biological processes, such as cell / tissue development.
This, says NIST materials scientist Carl Simon, has led to a large and rapidly expanding collection of possible 3D scaffolds, ranging from relatively simple gels made of collagen, the body's natural structural matrix, to structured or unstructured arrangements of polymer fibers, hydrogels and many more.
Their results, published this week in Applied Physics Letters, from AIP Publishing, report that these nanoscale polymers, which are biocompatible, could have a wide range of biological applications such as for drug delivery scaffolds or miniature implantable sensors.
He has pioneered the development of porous polymers that can be assembled into ordered 2D - grids or 3D scaffolds.
The company's first product, Meniscofix ™, is a biodegradable polymer, fiber - reinforced scaffold for total meniscal replacement.
Osteogenic differentiation of mesenchymal progenitor cells in computer designed fibrin - polymer - ceramic scaffolds manufactured by fused deposition modeling.
Dynamics of in vitro polymer degradation of polycaprolactone - based scaffolds: Accelerated versus simulated physiological conditions.
We study cell (endothelial cells, fibroblasts, osteoblasts) guidance cues on biodegradable scaffolds (e.g. polymers).
Comparison of Human alveolar osteoblasts cultured on polymer - ceramic composite scaffolds and tissue culture plates.
Design, fabrication and physical characterization of scaffolds made from biodegradable synthetic polymers in combination with rp systems based on melt extrusion.
They had to find the right blend of polymers to be both flexible and strong, which turned out to be a one with long - chain polymers that have strands like spaghetti and one with shorter chain polymers that act like a scaffold.
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign
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