Sentences with phrase «polymerization of actin»

In cells, proteins that induce the polymerization of actin, such as the Arp2 / 3 complex, also control it.

Not exact matches

As a first demonstration, the Hopkins group examined cells before and after treating them with a compound that inhibits the polymerization of a protein called actin.

In a paper published this week in Current Biology, postdoctoral fellow David Kast, PhD, and professor Roberto Dominguez, PhD, and three other colleagues from the Department of Physiology at the Perelman School of Medicine at the University of Pennsylvania, show for the first time that the formation of ephemeral compartments key in this process require actin polymerization by the Arp2 / 3 complex, a composite of seven proteins.

The «fuel» for the biogenesis and movement of autophagosomes is provided by actin polymerization powered by the Arp2 / 3 complex, which is recruited to autophagosomes by WHAMM.

When the actin polymerization occurs at one spot on the surface of an autophagosome, which coincides with the location of WHAMM on these organelles, an actin comet tail is formed, and the rapid assembly / disassembly of the actin polymers «pushes» the autophagosome toward the lysosome for final processing.

The rockets work like this: A protein anchored to the bacterium's membrane triggers the rapid polymerization of the protein actin; this provides an explosive boost, so the bacterium can push through the membrane of white blood cells and burst out to infect another cell.

One possibility is that it acts directly to enhance the polymerization of tubulin and actin, the monomeric proteins that give rise respectively to microtubules and micro filaments.

Coordination between membrane trafficking and actin polymerization is fundamental in cell migration, but a dynamic view of the underlying molecular mechanisms is still missing.

Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP.

Since the viscosity of actin solution increases due to polymerization, the rate was accessible.

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2 - mediated Rac activation and actin polymerization.

Localization of all seven messenger RNAs for the actin - polymerization nucleator Arp2 / 3 complex in the protrusions of fibroblasts.

The Wiskott - Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF - $ ąppa $ B (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement.

I was measuring how the presence of certain proteins influences the polymerization rate of actin filaments.

Defects in nuclear actin polymerization and myosin motor function result in heterochromatin repair defects and widespread chromosome rearrangements, revealing the importance of the relocalization pathway in genome integrity.

«George was one of the first biophysicists who married experiments and theory by developing computational models of a bewildering variety of molecular machines — kinesin motor, flagellar rotary motor, RNA polymerase and protein translocation motors, «one - shot» actin polymerization motor and «slime - gun» motor of bacterial gliding,» Magilner said.