Sentences with phrase «polymorphism in»
Polymorphism in serotonin transporter gene associated with susceptibility to major depression
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Association analysis between a functional polymorphism in the monoamine oxidase A gene promoter and severe mood disorders
A study of the association of (Val66Met) polymorphism in the brain - derived neurotrophic factor gene with alcohol dependence and extreme violence in Chinese males
Fowler et al. (2009) found that a variable number tandem repeat (VNTR) polymorphism in the gene encoding monoamine oxidase A (responsible for catabolism of serotonin and other catecholamine neurotransmitters), and an insertion / deletion polymorphism in the SLC6A4 promoter (5 - HTTLPR) were associated with what the authors term the «emotional dysfunction» aspect of psychopathy (a construct that corresponds with CU traits) in a sample of adolescents with attention deficit hyperactivity disorder (ADHD)[18].
A meta - analysis of association studies between the 10 - repeat allele of a VNTR polymorphism in the 3 ′ UTR of dopamine transporter gene and attention deficit hyperactivity disorder
Previous research has reported that a functional polymorphism in the monoamine oxidase A (MAOA) gene promoter can moderate the association between early life adversity and increased risk for violence and antisocial behavior.
We tested the hypothesis that a repeat polymorphism in the rhesus macaque MAOA gene promoter region influences aggressive behavior in male subjects.
In conclusion, despite its limitations, this study supports and extends the findings of previous reports showing that the MAOA polymorphism in combination with early experience modulates individual proclivity to later - life physical aggression.
Bax promoter G (－ 248) A polymorphism in a Turkish clinical breast cancer patients: A case - control study
Interleukin - 10 gene promoter polymorphism in patients with schizophrenia in a region of East Turkey
However, researchers at the University of California — Berkeley wanted to find out if there might a genetic component that could predict how couple interactions affect marital satisfaction.5 Specifically, the team decided to look at the 5 - HTTLPR polymorphism in the promoter region of the serotonin transporter gene.
We studied the well known functional polymorphism in the 5 ′ flanking regulatory (promoter) region of the gene (SLC6A4) coding for the serotonin transporter protein.
For those of you not on Team Cilantro, consider this your talking points... and impress your naysaying cilantro - loving friends by boasting about your unique version of a single - nucleotide polymorphism in the area of chromosome 11!
The same authors examined this slc1a2 polymorphism in shiba inu and found dogs with the genotype CC were significantly less aggressive to strangers than those with a genotype TC.
Meta - analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity.
: To investigate whether the +1730 G / A polymorphism in the estrogen receptor (ER)- beta gene is associated with susceptibility to polycystic ovary syndrome (PCOS).
Similarly, in a rodent model of PCOS, levels of ERβ protein were decreased in the granulosa layers of cystic follicles.67 Idiopathic ovulatory dysfunction has been found to be associated with a G / A (1730) polymorphism in ERβ.2.
MAIN OUTCOME MEASURE (S): Genotype distribution and allele frequency of the +1730 G / A polymorphism in the ER - beta gene.
This study analyzes the correlates of two genetic polymorphisms, the TaqI A polymorphism in the dopamine receptor D2 (DRD2) gene and the 48 base pair (bp) repeat polymorphism in the dopamine receptor D4 (DRD4) gene.
Recently Corbett - Detig et al found evidence that linked selection strongly constrains levels of polymorphism in species with large census sizes.
Because the data do not fit theoretical null distributions, attempts to infer natural selection from polymorphism data will require genome - wide surveys of polymorphism in order to identify anomalous regions.
We genotyped the APOBEC3A / B deletion polymorphism in a large population based sample consisting of 11,106 Caucasian (Norwegian) individuals, including 7,279 incident cancer cases (1,769 breast -, 1,360 lung -, 1,585 colon -, and 2,565 prostate cancer) and a control group of 3,827 matched individuals without cancer (1,918 females and 1,909 males) from the same population.
A natural A → G polymorphism in the XMRV genome [23], [38] is present at position 790 (cyan lollipop).
In a proof of principle study, we found that a previously undescribed single nucleotide polymorphism in the binding domain of the erythrocyte binding like protein (EBL) conferred a dramatic change in red blood cell invasion in mutant rodent malaria parasites Plasmodium yoelii.
94/3: 15 A survey of DNA methylation polymorphism in the human genome identifies environmentally responsive co-regulated networks of epigenetic variation.
Tristan Ferroir et al., «Carbon Polymorphism in Shocked Meteorites: Evidence for New Natural Ultrahard Phases,» Earth and Planetary Science Letters, Vol.
- Polymorphism in Fibronectin Binding Protein A in Staphylococcus Aureus are Associated with Infection in Cardiovascular Devices; Vance Fowler, MD, Duke.
After a chance discovery, another polymorphism in the dopamine D4 receptor gene is linked to attention deficit hyperactivity disorder
An advantage of clear over white egg mass morphs in metabolically demanding microhabitats suggests a role of symbiotic algae in the maintenance of a polymorphism in the spotted salamander (Ambystoma maculatum).
Its application to a model system of symmetric tilt boundaries in Cu uncovers an unexpected rich polymorphism in the grain boundary structures.
Association between functional polymorphism in EGF gene and malignant melanoma.
Leu7Pro polymorphism in the neuropeptide Y (NPY) gene is associated with impaired glucose tolerance and type 2 diabetes in Swedish men
Furthermore, another polymorphism in women was found to be associated with elevated first - phase insulin secretion (193).
Pro12Ala polymorphism in the peroxisome proliferator - activated receptor - γ2 (PPARγ2) is associated with higher levels of total cholesterol and LDL - cholesterol in male caucasian type 2 diabetes patients
the presence of this mitochondrial sequence polymorphism in mice homozygous for the ahl allele results in age related hearing loss by 3 months of age, which is absent when the CAST / Ei mitochondrial sequence is instead present
Dr. Rotimi's lab has shown that a polymorphism in the endothelial nitric oxide gene is associated with diabetic retinopathy in Africans.
A scan for human - specific relaxation of negative selection reveals unexpected polymorphism in proteasome genes Somel, M., M. A. W. Sayres, G. Jordan, E. Huerta - Sanchez et al. 2013.
Genome - wide patterns of nucleotide polymorphism in domesticated rice.
Genome - wide patterns of nucleotide polymorphism in domesticated rice Caicedo, A. L., S. H. Williamson, R. D. Hernandez, A. Boyko et al. 2007.
A scan for human - specific relaxation of negative selection reveals unexpected polymorphism in proteasome genes.
Behavioural scores, however, were not correlated with this polymorphism in our population.
High blood pressure, for instance, has been linked to a polymorphism in the angiotensinogen gene that increases a person's sensitivity to salt.
A functional polymorphism in the promoter region of the human serotonin transporter gene (SLC6A4) has been associated with several dimensions of neuroticism and psychopathology, especially anxiety traits, but the predictive value of this genotype against these complex behaviors has been inconsistent.
«What we found is that if people have a specific polymorphism in the BDNF gene, they recovered to a greater extent than those with a different variant of the gene.»
The other part of the atlas was a physical map of the genome created by a group of researchers from the Center for the Study of Human Polymorphism in Paris.
DNA polymorphism in the Y chromosome, examined at a 729 - base pair intron located immediately upstream of the ZFY zinc - finger exon, revealed no sequence variation in a worldwide sample of 38 human males.
CONCLUSIONS: The common polymorphisms in MTHFR are not associated with embryo quality or with short - term pregnancy outcomes.
Identification of novel polymorphisms in the glucokinase and glucose -6-phosphatase genes in infants who died suddenly and unexpectedly
It has been estimated that 5 % to 10 % of infants who die from SIDS have novel mutations in the cardiac sodium or potassium channel genes that result in long QT syndrome as well as in other genes that regulate channel function.44 A recent report described important new molecular and functional evidence that implicates specific SCN5A (sodium channel gene) β subunits in SIDS pathogenesis.47 The identification of polymorphisms in genes pertinent to the embryologic origin of the autonomic nervous system in SIDS cases also lends support to the hypothesis that a genetic predisposition contributes to the etiology of SIDS.
Predisposition to vascular disease was my focus here, using genetic epidemiological studies to identify novel polymorphisms in a range of candidate genes.