A second study in the journal also suggests that there could be a window of opportunity during childhood to reduce the risk of
poor lung function in later life.
The authors found that around three - quarters of infants aged one to six months
with poor lung function improved throughout their childhood, indicating a window of opportunity to increase lung function and potentially reduce risk of COPD in later life.
Three - quarters of chronic obstructive pulmonary disease (COPD) cases have their origins in
poor lung function pathways beginning in childhood.
«Maternal smoking in pregnancy may set children with asthma on a trajectory
of poor lung function in later childhood, and other studies suggest this effect may be lifelong,» Whittaker Brown said in a journal news release.
«Reduction of maternal smoke exposure and personal smoking and promotion of immunisation are identified as public health targets to
prevent poor lung function pathways.
The multisite team, led by researchers from the University of Alabama at Birmingham, suggests that ECAC, as measured by computed tomography scanning, is associated
with poor lung function and respiratory symptoms.
Respiratory acidosis is a result
of poor lung function, which leaves blood over-saturated with carbon dioxide.
Stronger associations between higher levels of pollution around pregnant women and
poorer lung function in their subsequent children appeared among allergic children and those of lower social class.
Over time, the lung is changed by secretions from the M2 cells, which cause the lung tissue to remodel itself, contributing to irreversible obstruction and
poor lung function.
«It has long been thought that ECAC did not contribute to
poor lung function or respiratory symptoms,» said Surya Bhatt, M.D., assistant professor in the Division of Pulmonary, Allergy and Critical Care Medicine at UAB and lead author of the study.
«As we learn more about improving asthma outcomes in children, it is important to find out not only what environmental exposures are implicated in
poor lung function, but also when those exposures are most harmful,» Whittaker Brown said.
Tramadol should never be given to dogs with kidney disease, a poorly functioning liver, a history of seizures, or
poor lung function.