Sentences with phrase «poor survival»

A major reason for poor survival rates is late diagnoses, by which time the cancer cells have spread to secondary sites.

Patients whose tumors had a gene - expression signature associated with poor survival lived for a period that was 23 percent shorter than patients whose tumors did not have such a signature.

This is the first study to suggest that red blood cell transfusions from young donors and from female donors may be associated with poorer survival in recipients.

Baseline health - related QoL scores predicted very poor survival among a subset of women with PRR - ROC, and together with prognostic clinical factors like hemoglobin, ascites, neutrophil - to - lymphocyte ratio, platelet counts, and serum CA - 125, improved overall survival prediction.

DENVER — Leptomeningeal metastases (LM), a devastating complication and predictor of poor survival in lung cancer patients, was found to be more prevalent in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations.

The event was a great success, but the only problem was that many of the plants that were planted in the woods had a very poor survival rate, because the rains had lessened and the soil was starting to dry up.

Among patients with metastatic breast cancer, high evening levels and low diurnal deviation characterized patients compared with healthy controls, and low diurnal deviation predicted poorer survival.

Deshpande aims to make a big impact with this work — he's first focusing on a group of acute myeloid leukemia (AML) with very poor survival outcomes.

Some historical evidence suggests that, in ancient times, first babies had particularly poor survival rates, and slow lactogenesis following a first birth may have been a significant part of it.

Study leader Dr Jessica Petrick, said: «This study highlights how weight gain over the course of our lives can increase the risk of developing these two cancer types, both of which have extremely poor survival.

Patients with comorbidity were found to have poorer survival at each stage, he said, and the difference in survival between patients with and without comorbidity seemed to be greater in less advanced stages.

«To give crude data on the survival rate among all such infants, regardless of whether treatment efforts were made, is misleading and helps to make poor survival a self - fulfilling prophecy.»

«This could lead to a more aggressive cancer and worse outcomes for cancer patients ─ poorer survival rates.»

Although low - protein foods translate into poorer survival for many organisms, «this locust is king of what we typically consider to be junk food,» Cease explains.

Patients choosing nodal observation, but ultimately requiring delayed lymphadenectomy, risk unresectable regional recurrence and increased morbidity, a longer stay in the hospital, and potentially poorer survival.

Despite intensive efforts to improve BC treatments, patients with TN BC still exhibit poor survival, with half developing resistance to chemotherapy.

That means they have a high likelihood of disease recurrence and poor survival odds despite receiving standard chemotherapy and optimum surgery.

«At the same time, as the human ZNF217 is associated with poor survival in a variety of cancers, understanding how this protein operates in physiological conditions may help to predict cancer risk, achieve earlier diagnosis and provide novel therapeutic approaches.»

A protein called CSN6 has been found to be correlated with poor survival among patients with colorectal cancer, according to a study at The University of Texas MD Anderson Cancer Center.

In 25 % of subjects cirrhosis was apparent at first diagnosis was determined to be a predictor of poor survival and need for liver transplantation.

Higher levels of hypoxia in a tumour are strongly linked to poor survival rates in cancer patients, he said, and hypoxic tumours are often resistant to treatment.

AML is an aggressive blood cancer characterised by an accumulation of dysfunctional blood cells in the body, and AML diagnosis is often associated with poor survival.

«Poor survival among colorectal cancer patients tied to biomarker csn6.»

«Patients with colon cancer lacking in AIM2 have been found to have poor survival, but we have identified a possible personalized therapeutic strategy to help them,» said Jenny Ting, William R. Kenan Jr..

The study also indicated that genomic diversity may also have useful clinical applications for predicting tumor invasion, metastasis and poor survival in patients.

Cancer stem cells survive after chemotherapy and radiation treatment and are associated with recurrence, metastasis and poor survival in clinical trials.

In addition, alterations in the expression of enzymes that change the methylation of histones have been linked to disease and poor survival in a variety of conditions.

Poor survival of in vitro embryos may have contributed to the pessimistic view about natural human embryo survival, says Dr Jarvis.

One of the molecular partners is annexin A2, a protein that scientists say was already linked to poor survival rates in these cancers.

«Recurrent or metastatic cervix cancer is really difficult to treat with a low response rate and poor survival.

«This study suggests that reluctance to insure prescription drugs may result in increased recurrence and poor survival among women with breast cancer, one of the largest groups of cancer survivors.»

Esophageal cancer is increasing in prevalence and has poor survival rates, particularly in less - developed regions and for men.

Kidney dysfunction is a frequent complication affecting more than 50 percent of all cancer patients, and is directly linked to poor survival.

We identified and validated 6 immunologically distinct subgroups, with the largest having the lowest immune scores and the poorest survival.

The poor survival in advanced ovarian cancer is due both to late diagnosis, as well as to the lack of effective second - line therapy for patients who relapse.

Several retrospective studies have suggested a correlation between pSTAT3 expression in colorectal cancer and poor survival.

Patients with chronic myeloid leukemia in the blast phase pose a significant therapeutic challenge and have poor survival, even in the tyrosine kinase inhibitor era, according to a new study.

Increased expression of inflammatory cytokines correlates with higher tumor grade, greater metastatic potential, and higher incidence of resistance to treatment, all of which predict a poorer survival.

«Since reduced AIM2 activity in colorectal cancer patients is associated with poor survival, it might be useful to detect the level of AIM2 expression in polyps taken from colonoscopy and use this as one of the biomarkers for prognosis,» Kanneganti said.

TCGA researchers also established how sets of genes are expressed in a fashion that can predict patient survival - identifying patterns for 108 genes associated with poor survival and 85 genes associated with better survival.

Poznansky adds that the tumors that might be treated with the mesothelin - targeting vaccine — ovarian cancer, pancreatic cancer and mesothelioma — all have poor survival rates.

Improving the quality and quantity of research into cancers with the poorest survival rates, including brain and pancreatic cancers, remains a key priority across all aspects of our research activity.

Stage IV cancer is the most advanced form of the disease, and usually has a poor survival rate in comparison to earlier stages of the disease.

That's important, since studies hint at a link between obesity and poorer survival rates among women who've had breast cancer.

It is an important time to make a distinction between a healthy, young or adult cat that is in this category from one that is a young kitten or very sick homeless cat; these have poor survival rates in the «wild» and they may be best candidates for trapping or catching and taking in to shelters.

Pups less than 8 days old have a poor survival rate, but you should still try.

Puppies born to malnourished dogs have reduced birth weights, are prone to hypoglycemia, and have poor survival rates (Schroeder et al., 1994).