The cells exhibited many functions associated with tumor progression; their presence within mouse tumors substantially accelerated cancer
growth, and in human
lung tumors, a SiglecFhigh neutrophil signature was associated with
poor patient survival.
DENVER — Leptomeningeal metastases (LM), a devastating complication and predictor of
poor survival in
lung cancer patients, was found to be more prevalent in non-small cell
lung cancer (NSCLC) patients with epidermal
growth factor receptor (EGFR) mutations.