Reporting their laboratory findings in the journal Aging, the team observed that addition of DPI to a mixed
population of cells eliminated the tumour initiating cancer stem cells.
Not exact matches
In order to eradicate those HIV reservoirs, researchers must find a way to
eliminate persistent
populations of cells with integrated HIV proviruses.
The study, which appears August 3 in the peer - reviewed journal Nature Communications, showed that pairing the chemotherapy with an experimental drug
eliminates the deadly
population of cells believed to be responsible for repopulating the tumor.
This murine model system offers a superior source
of immortalized
cell populations as many
of the difficulties associated with the in vitro transfection process are
eliminated (e.g., initial requirement for many
cells, different sites
of gene integration, multiple copy number; Ref.
Here, we elaborate on how these findings pertain to cancer
cells dispersed in the tumor - adjacent stroma
of breast cancer tissues, and how BH3 - mimetics may provide a therapeutic strategy to
eliminate cancer
cell populations that have passed through an EMT.