Sentences with phrase «population of patients who»

This means there's a large population of patients who may be eligible to take pan beta blockers while being treated with immunotherapy.

Commenting on the results, Dr Andrés Poveda, head of the Gynaecological Cancer Clinic, Oncology Foundation Institute Valencia, Spain, said: «This study more than doubles the population of patients who benefit from a PARP inhibitor.»

No Association Between Response Rates and Survival in Newly Diagnosed Multiple Myeloma: Results of a recent meta - regression analysis of 63 randomized clinical trials out of Greece concluded that there was no association between conventional response outcomes, such as complete response (CR) or very good partial response (VGPR), and overall (OS) or progression - free survival (PFS) in patients with newly diagnosed multiple myeloma in populations of patients who received stem cell transplant and those who did not.

Not exact matches

The country's ageing population is creating lots of demand in healthcare, including for those who dispense medication and monitor patient health

The Pittsburgh - based specialty pharmacy grew its revenue by 13,380 percent in three years to $ 42 million by focusing on the small populations of underserved patients who need orphan drugs to treat serious illnesses.

Once she can start aggregating data from her patients with data from other doctors who are using the app, she will have a huge number of data points that she can use to track everything from the efficacy of the surgery in certain patient populations, to which doctors might get the best outcomes.

Both of these types of organizations, among others, tend to have diverse populations, it would be nothing short of doctrinaire to impose a particular religious dogma on the medical care of everyone who is a patient, a student or an employee.

As a general internist who has cared for patients at Bellevue Hospital in New York, Dr. Shah knows firsthand the impact on vulnerable populations of inadequate resources.

The FDA also expanded the approval of pembrolizumab to treat the majority of people with NSCLC who had received prior chemotherapy, greatly increasing the patient population that can benefit from the treatment.

One of the four outlets had patients who were significantly younger than the local population, and three of the four had more male customers than expected and a different mix of race and ethnicity.

And since a medical condition with an apparent patient population of one could hardly garner federal funding, Rienhoff recast himself as a citizen scientist, a do - it - yourselfer who now finally has a candidate gene in hand.

While based on nationwide data, the study was limited to patients in the VA system, who may differ from the general population of ulcerative colitis patients.

He specifically wants to expand the population of stem cells that will induce regeneration of neurons and blood vessels in patients who have suffered a hemorrhagic stroke, the kind of stroke which is caused by blood clot.

Median follow - up time from randomization for the entire patient population was 4.2 years, and findings reflect the 866 patients who reached two - year follow - up at the time of reporting in May 2016.

If a bacterial population can become antibiotic - resistant even when only a small number of individuals have the appropriate genetic mutations, doctors who collect and analyze small bacterial specimens from patients may underestimate just how resistant the infection is as a whole, Collins notes.

According to the nationally representative study, patients who will gain Medicaid under expansion programs supported by the ACA will be younger (average age of 36 versus 38), with a larger proportion being male (49 percent versus 33 percent) and white (60 percent versus 50 percent) compared to the current Medicaid population.

«The patient population that is indicated for bariatric surgery is different than the universe of patients who are just morbidly obese.

«Today, people who have been given a new heart experience increased physical function, quality of life, and overall life span; however, most patients continue to have limitations in their physical function and reduced quality of life compared to the general population due to side - effects from anti-rejection medications and because heart rate regulation is impaired after heart transplantation,» said Dall.

The combination should be studied in other populations of patients, Adelson added, including those who are newly diagnosed with metastatic breast cancer and those who have already progressed on fulvestrant.

They noted that 27 (15 percent) of trauma centers serve a population that is more than 50 percent minority, while 154 have patients who are predominantly white.

If so, says Grover Bagby, a hematologist who directs the Oregon Cancer Center at the Oregon Health Sciences University in Portland, further work to decipher the protein's exact function could shed light on how to treat a much larger population of patients with leukemia, certain other forms of cancer, and aplastic anemia.

Future research should look at data from state prescription drug monitoring programs and data on other substance use to get a more comprehensive view of how patients are using opioids,» said Karen E Lasser, MD, MPH, a general internist at BMC with expertise in improving the quality of care for underserved patient populations, who served as co-principal investigator of the study.

• 25.3 % of COPD patients from other populations had heart failure compared to 11.3 % in their counterparts who did not have COPD.

«The patients who sought care for chronic breathlessness appeared to have a significantly impaired quality of life than the general population.

Patient recruitment is an enormous problem in many medical studies, and researchers often end up paying for the participation of students, poor people, drug abusers, the homeless, illegal immigrants, and others who may not adequately represent the population in terms of health or lifestyle.

«It's not just for the individual patient, but for the larger population, by reducing transmission of HIV to the general community,» said Philippa Easterbrook, a scientist with the WHO, at a briefing on the new plan last week in London.

«In our large population - based study of more than 6,000 adults with CAP and almost 30,000 matched controls, we found that CAP patients have high rates of long - term morbidity and mortality compared to those who have never had CAP, irrespective of their age.»

ACS occurred in the general population at a rate of 3.3 / 1,000 person - years, compared to 5.7 / 1,000 person - years among those patients with RA actively on TNF inhibitor treatment and 8.6 / 1,000 person - years among those with RA who had never taken a biologic medication.

The authors of the current study hypothesize that these previous trials may have inadvertently selected subjects who would be nonresponsive to the medication and conclude that future efficacy trials may require the identification of subgroups of patient populations.

Providers that receive additional payments for population management or care coordination could use some of those resources to coordinate care with health supporters who are playing key roles in chronically ill patients» health management.

«The results of our study could offer new treatment to this population of patients, identifying a subset of malignant pleural mesothelioma who expressed PD - L1 and could be treated with targeted therapies to PD - L1,» Cedres says.

By tuning the model to replicate population data, such as the number of people at risk for developing TB and the fraction of TB patients who have drug resistance, the model can predict changes in the TB disease burden — or number of cases — over many years.

Böhm recommends additional research to demonstrate the efficacy of renal denervation and to identify the patient populations who might benefit most from the procedure.

A new population - based study has found that patients with glioblastoma who died in 2010, after the Food and Drug Administration (FDA) approval of bevacizumab, had lived significantly longer than patients who died of the disease in 2008, prior to the conditional approval of the drug for the treatment of the deadly brain cancer.

China has many times more people who have strokes every year than the United States because of the size of the population and higher stroke rates, which allowed investigators to screen 41,561 patients in just three years at the 114 clinical sites, and enroll 5,170 patients in the trial.

To determine whether scientific studies since 2002 found additional evidence on the usefulness of omega - 3 fish oil supplements, the authors focused on studies related to preventing a first heart attack in the general population, or in patients who were at high risk for heart disease, and preventing recurrent events and death in patients who had a prior heart attack, congestive heart failure, stroke, or atrial fibrillation.

«Our findings provide the first general population - based evidence that osteoarthritis patients who have total knee or total hip replacement surgery are at increased risk of heart attack in the immediate postoperative period,» concludes Dr. Zhang.

In one study, Okunrintemi and colleagues evaluated patient experience, healthcare expenditure and resource use in a large population of adult cardiovascular disease patients, dividing them into two groups: those who had been diagnosed with depression and those who had not been diagnosed with depression.

But patients who had neurological infections had a higher risk of dying of some other diseases than the general population.

«Recently, analyses of patients who received checkpoint blockade identified neutrophil - to - lymphocyte ratio < 3 and normal lactate dehydrogenase as positive predictors of response; however, in our lymphodepleted patient population, neither separated patients who achieved responses from those who did not clearly enough to warrant use as an inclusion criterion,» the researchers wrote.

«Remarkably, the advantage of 15 - mg / kg ATLG over the 30 - mg / kg dose was evident in patients transplanted from donors with one or more HLA disparities, who represented almost half of the study population,» the researchers wrote.

«Here we see that the same IL - 21B gene polymorphisms seem to influence the response to influenza virus vaccination, at least in a population of transplant patients who, because of their transplant status, have to receive immunosuppressing drugs.

One possible explanation for any improvements seen in the survival of patients who stop smoking might be a reduction in mortality from cardiorespiratory causes, as the risk of death from these diseases reduces after cessation.9 18 Consequently, we estimated the expected contribution of cardiovascular and respiratory diseases by using life tables as above to find the number of cardiorespiratory deaths prevented by smoking cessation in the general population.

Because humans are born with a stable population of RPE cells that stay put throughout life, the researchers expected that fixing the cells once would make a lasting impact — and indeed, the vision of patients who got the therapy improved after a single treatment.

The resulting sample, however, may represent a population of alcohol - dependent patients who could be treated within a medical setting in which health care professionals are in a unique position to intervene, given their ongoing relationships with patients.

Label the FDA approved label is the official description of a drug product which includes indication (what the drug is used for); who should take it; adverse events (side effects); instructions for uses in pregnancy, children, and other populations; and safety information for the patient.

Further research is warranted to determine whether, in fact, the antisense strategy to target hepatic ApoC - III will result in the lowering of CVD risk in patients with mild - to - moderate hypertriglyceridemic, who comprise approximately 28 % of the general population (41).

The team also followed a group of patients in the early stages of HD and, for comparison, a control population who did not carry the HD mutation.

The current study can be compared to that of Young and Schmidt, who investigated changing bacterial populations in stool samples from a single patient with self - resolving AAD subsequent to amoxicillin - clavulanic acid treatment [82].

«However, given the prevalence of depression, anxiety, and suicidal ideation / suicide in the general population, and especially the adolescent population who may be candidates for isotretinoin therapy,» state AAD guidelines for the use of the acne medication, «the prescribing physician should continue to monitor for these symptoms and make therapeutic decisions within the context of each individual patient.»