Sentences with phrase «populations of cells from»

Not exact matches

And with 7billion on the planet (and growing), these «young people missing millions from their generation» should be thankful that clusters of cells can be medically removed, preventing unwanted births and (perhaps) even saving the human population from growing to a point of unsustainability.

In the clearest possible case, the ANT - OAR cell would differ from a zygote on all of the parameters noted above: The ANT - OAR cell would have a pattern of gene expression that is clearly distinct from a zygote; it would generate a homogeneous population of cells rather than multiple cell types; it would undergo simple cleavage divisions and not produce any multicellular structures.

I know it's popular to think of movies where Floyd is sharing his cell with a hardened criminal and having to worry about being shanked, but it's much more likely that he spends a bunch of time away from general population, being kept safe and probably watching TV and reading his days away.

Sampling was conducted via a stratified dual frame probability sample of landline and cell phone telephone numbers (both from Survey Sampling International) from within New York State weighted to reflect known population patterns.

They're not the only ones, of course, since political organizers from Manila to D.C. have found that cell phones are profoundly political devices, particularly when they reach populations that are otherwise effectively off the grid.

Sampling was conducted via a stratified dual frame probability sample provided by Survey Sampling International of landline and cell phone telephone numbers from within New York State weighted to reflect known population patterns.

However, the MIT team adapted it to randomly turn on or off distinct gene sets across large populations of cells, allowing the researchers to identify genes that protect cells from a protein associated with Parkinson's disease.

In the course of examining single unit responses from the cortex of unrestrained and unanesthetized cats, we have come upon a population of cells that appears to be sensitive to auditory stimuli only if the cat «pays attention» to the sound source.

Through a variety of «high tech» approaches, including the isolation of monoclonal antibodies from single B cells and ultra-deep sequencing of shifting viral populations over more than three years of infection, the researchers studied one woman who developed potent broadly neutralizing antibodies.

In order to thoroughly investigate cures for a diverse population, cell lines from a large sampling of individuals are needed.

We don't need to use a cocktail of small molecules, growth factors or other supplements to create a population of bone cells from human pluripotent stem cells like induced pluripotent stem cells,» Varghese said.

He then evaluated the levels of specific microRNAs in populations of highly metastatic, compared to poorly metastatic, cancer cells taken from the same patient.

Although some teams have managed to produce nearly pure colonies of certain kinds of neural cells from ES cells, no one has managed to concoct a recipe that will direct the cells to become, say, a pure population of dopamine - producing neurons that could replace those missing in Parkinson's disease.

Next, they used a technique called fluorescence - activated cell sorting to separate out the newly differentiated retinal ganglion cells from a mixture of different cells into a highly purified cell population for study.

Dr Ignacio Vazquez - Garcia, the first author from the Wellcome Trust Sanger Institute and University of Cambridge, said: «We found that the degree of diversity within the cell population — known as clonal heterogeneity — played a major role in the acquisition of antimicrobial resistance.

Professor Gianni Liti, a senior author on the paper from the Institute for Research on Cancer and Ageing, Nice, said: «We were able to study the evolution in time by combining genome sequences of the cell populations and tracking the growth characteristics of the yeast cells.

By varying the compositions of lipids, cues, and diffusible factors in the scaffolds, we engineered a very versatile and flexible platform that can be used to amplify specific T cell populations from blood samples, and that could be deployed in existing therapies such as CAR - T cell therapies,» said Mooney, Ph.D., a Core Faculty member at the Wyss Institute and leader of its Immunomaterials Platform.

Using only the DNA from sloughed - off cells floating in the ocean, scientists have been able to determine the population size and genetic properties of one of the world's largest and most mysterious animals: the whale shark.

Using fluorescent markers, Fuchs and her colleagues isolated two distinct populations of stem cells from mouse skin.

«The recent discovery of tumor - promoting milieus, referred to as metastatic niches, that are established at distant sites prior to or upon the arrival of disseminated tumor cells could explain cancer cells that relapse early, but in late relapsing populations, what tumor cells do from the time of dissemination to the time they become clinically detectable has been a big question.»

The research team with international collaborators analysed more than 100 patient samples from ovarian and other cancer types to discover a distinct population of cells found in some tumours.

«By combining the genetic analysis of a small population of immune cells from healthy skin with functional experiments we were able to define two subgroups of memory immune cell and in detail decipher / dissect how these cells behave in healthy and inflamed skin,» explains Liv Eidsmo, researcher at Karolinska Institutet's Department of Medicine.

Moreover, the stressed mice's gray hairs and the cell populations in their follicles were indistinguishable from those of elderly mice, suggesting that genotoxic stress might drive natural graying as well.

National Institutes of Health researchers studying zebrafish have determined that a population of cells that protect the brain against diseases and harmful substances are not immune cells, as had previously been thought, but instead likely arise from the lining of the circulatory system.

In the cases, just this last couple of elections, where stem cell politics, for example, has been played out in the electoral process, stem cell research is [has] done better than the winning candidates for offices; and I think, apart from that, I think that we do have a serious problem in general education of the sciences and that accounts for the reluctance of a large segment of the population to accept the principles of evolution and think that there is still a debate about it, which there isn't — and that's a problem we need to solve, — but I still think there is an incredible constituency for science in this country.

Dr Saraswat explained that the impact of endometriosis — a relatively common condition in which cells from the lining of the uterus (endometrium) are found elsewhere in the pelvic area — is relatively unknown in pregnancy in general populations of women, with most studies performed in infertile women having assisted reproduction.

Conservation work to defeat the disease has including removing infected individuals from the population and new research in Evolutionary Applications explains how this gives us a unique opportunity to understand how human selection alters the evolution of cancerous cells.

DFTD is an asexually reproducing clonal cell line, which during the last 16 years has been exposed to negative effects as infected devils, approximately 33 % of the population, have been removed from one site, the Forestier Peninsula, in Tasmania between 2006 and 2010.

Lepidoptera genetics is notorious for the fact that chromosome counts can vary between populations of the same species and occasionally even within cells from the same individual, he explains.

The team also demonstrated the utility of the platform by applying it to examine a growth - modulating feedback circuit whose dynamics is qualitatively altered by circuit - host couplings and revealing the behaviors of a toggle switch across scales from single - cell dynamics to population structure and to spatial ecology.

With the results from both Korea and the UK the presence of both diet and microbe - induced populations of pTreg cells may be required for the development of complete tolerance to food antigens.

Microfluidic tools for precision measurements of cell migration speed reveal that migratory speed of individual cells changes stochastically from parent cells to their descendants, while the average speed of the cell population remains constant through successive generations.

The second branch of the combination therapy, the low - dose metronomic chemotherapy, was similarly found to exert its therapeutic effect through a novel, hitherto unrecognized mechanism: The metronomic chemotherapy turned out to not primarily target the tumor cells, but to act on the recruitment of yet another tumor - promoting cell population from the bone marrow.

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

The researchers tested the drug on mice with H. pylori infections from several different cell lines, and found that the drug was effective against the H. pylori while maintaining populations of healthy gut bacteria.

Researchers at the Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem — Inserm / AFM / UEVE), in collaboration with CNRS and Paris Descartes University, have recently developed a new approach to better control the differentiation of human pluripotent stem cells, and thus produce different populations of motor neurons from these cells in only 14 days.

Developing therapeutic cell populations from human ES cells will be far more demanding: cells will have to be stable, predictable, pure, have proven functionality, be nontumor - forming, and be «scalable» — capable of growing in very large numbers.

Western Pygmies I love population genetics for its ability to peer back into human history through the medium of DNA's ATCGs.One of the stars of this discipline is Sarah Tishkoff, a standout in African genetics, someone who will readily haul a centrifuge into the bush in Cameroon.Tishkoff of the University of Pennsylvania is lead author on a paper published online July 26 in Cell that details whole - genome sequencing of five individuals each from three extant hunter - gatherer groups — the Pygmies of Cameroon as well as the Hadza and the Sandawe of Tanzania.

The new study from Tonegawa's group builds on previous research demonstrating that episodic memories are physically represented in populations of cells in parts of the hippocampus.

To further clarify this notion, we examined the specificity of miR - 7 expression in CSCs and non-stem cell population from MDA - MB231, 231BoM, and 231BrM.

«We wanted to know if eradication of this very small population of stem cells would improve organ function, and both kidney and heart were completely protected from developing fibrosis - related complications (e.g., kidney failure and heart failure),» said Humphreys, who also heads the Onco - Nephrology Program at the Dana - Farber Cancer Institute.

The selection strategy targeted cell populations expressing the inducible endothelial cell adhesion molecules, E-selectin and VCAM - 1, and proved successful in generating microvascular endothelial cell lines from a number of different organs.

Perigonadal adipose tissue was collected from female B6.V Lepob / ob mice, digested, and centrifuged to yield a buoyant adipocyte - enriched cell population (gray bars) and a pellet of SVCs.

Thus, our selection strategies, which were based on targeting endothelial populations that expressed both of these inducible glycoproteins, suggest that the endothelial cell lines generated in this study are most likely from this microcirculatory region.

Expression analysis of macrophage and nonmacrophage cell populations isolated from adipose tissue showed that adipose tissue macrophages are the primary sources of TNF - α and other proinflammatory molecules in adipose tissue.

Once endothelial cells are removed from a heterogeneous population of cells, it is often difficult to obtain a sufficient number of cells for experimental analysis.

To determine whether adipose tissue macrophages express any molecules implicated in obesity - associated complications, we isolated three cell populations from the parametrial adipose tissue of three obese B6.V Lepob / ob mice: (a) an adipocyte - enriched population, (b) a stromal vascular macrophage F4 / 80 + population, and (c) an F4 / 80 — stromal vascular population.

Researchers at the Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem — Inserm / AFM / UEVE) have recently developed a new approach to produce different populations of motor neurons from these cells in only 14 days.

From these you can now obtain an arsenal of viral factors, lentiviruses or retroviruses, and it's actually a starting cell population of choice.

In this study, we used an in vivo strategy to determine if functional retinas could be generated from a defined population of pluripotent Xenopus laevis cells.