Not exact matches
Alexion Reports First Quarter 2018 Results and
Positive Topline Data
from ALXN1210
Phase 3 PNH Switch Study
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from the build
phase to exit with the goal of helping create companies that have a strong
positive impact on the economic health of their local communities.
The internal
phase changes that separate matter
positive potential energy
from gravitation negative potential energy are no more mysterious than other
phase changes like separating ice
from water.
Thus «the supervention of the later
phases does not involve elimination by negative prehensions; such eliminations of
positive prehensions in the concrescent subject would divide that subject into many subjects, and would divide those many subjects
from the superject» (PR 240F).15
The first part of a possible Whiteheadian explanation for these phenomena consists in the fact that actual occasions making up, say, the eyes, are basically selective in «receiving» their data
from the external world due both to (i) the presence of negative as well as
positive prehension in the first
phase of concrescence (those that exclude and include data in the concrescence, respectively), and (ii) the activity of «transmutation» in a subsequent
phase.»
This is backed up by the contention that there is no elimination in subsequent
phases: «Thus the supervention of the later
phases does not involve elimination by negative prehensions; 13 such eliminations of
positive prehensions in the concrescent subject would divide that subject into many subjects, and would divide those many subjects
from the superject» (PR 240/368).
If it's a
positive omen you are after for Juventus, aiming to prevent Madrid
from reaching the final four for the first time since 2010, the last player to knock them out prior to that
phase was Lyon's Miralem Pjanic — who is now on the books at Juventus.
The
positive phase was suspected to be behind the 12 - year drought Australia has just emerged
from, as well as torrential rains that swept across East Africa in 1997.
Carbon monoxide has a simple but distinctive outermost orbital structure with two side - by - side lobes sticking out
from the end of the tip, one with a
positive phase and the other a negative
phase.
There are almost as many methods of training as there are trainers, but over time the basic strategy has shifted away
from punishment or avoidance training (negative reinforcement) to
positive reinforcement, where the dog is rewarded for doing the correct thing during most
phases of training rather than being punished for not doing what the trainer wants.
International researchers prospectively analyzed and compared tumor and matched plasma DNA for EGFR mutations
from 1060 patients that were screened as part of a
phase IV, open - label, single - arm, first - line gefitinib in EGFR mutation
positive Caucasian patients.
Researchers
from the University of California Irvine have shown that a phenomenon known as the Atlantic Multidecadal Oscillation (AMO)-- a natural pattern of variation in North Atlantic sea surface temperatures that switches between a
positive and negative
phase every 60 - 70 years — can affect an atmospheric circulation pattern, known as the North Atlantic Oscillation (NAO), that influences the temperature and precipitation over the Northern Hemisphere in winter.
Although just published in The Lancet, those findings have since been overtaken by strikingly
positive results
from the larger
phase III trials.
«To evaluate these findings in a group with only one HER2 treatment, we are currently analyzing data
from another clinical trial, the GeparQuinto clinical trial, which is a randomized,
phase III clinical trial evaluating two different neoadjuvant therapy regimens with a single anti-HER2 treatment [trastuzumab or lapatinib] for women with HER2 -
positive breast cancer,» said Loibl.
Thompson and Solomon (2002) showed that the Southern Annular Mode (a pattern of variability that affects the westerly winds around Antarctica) had been in a more
positive phase (stronger winds) in recent years, and that this acts as a barrier, preventing warmer air
from reaching the continent.
While this is still only interim data
from an early
phase trial, this study is a
positive result for Spark Therapeutics and Pfizer, as well as future patients.
CAMBRIDGE, Mass., April 27, 2017 — Moderna Therapeutics, a clinical stage biotechnology company that is pioneering messenger RNA (mRNA) Therapeutics ™ to create a new generation of transformative medicines for patients, today announced
positive interim data
from an ongoing
Phase 1 study of mRNA - 1440, an mRNA infectious disease vaccine against avian H10N8 influenza, demonstrating mRNA - 1440 induced high levels of immunogenicity, and was safe and well tolerated.
deCODE genetics (Nasdaq: DCGN) today announced
positive results
from its preliminary
Phase II clinical trial (
Phase IIa) of Cephalon Inc.'s (Nasdaq: CEPH) CEP - 1347 in asthma.
This approval will also allow ReNeuron to expand its ophthalmology program; it plans to soon apply to increase its
Phase I / II trial on RP
from six to 20 patients with a view to progress to a
Phase II / III on delivery of
positive data.
Regeneron Pharmaceuticals this week reported
positive results
from two
phase 3 trials of Eylea (aflibercept) injection for diabetic macular edema (DME).
Using reanalysis moisture budgets and drawing on the attribution work of others (e.g. Hendon et al. [2013]-RRB-, Fasullo et al. [2013] demonstrate that the 2011 La Niña was also distinct
from others in the altimeter era in that it coincided with a strong negative
phase of the Indian Ocean Dipole (IOD) and
positive phase of the Southern Annular Mode (SAM)(Fig. 3c).
The
positive safety profile to date, the evidence supporting engraftment of the cells post-implantation, and the improvements we are seeing in upper extremity motor function highlight the promising findings coming
from this
Phase 1 / 2a clinical trial, which will guide us as we work to design future studies.
GenSight Biologics announces publication of
positive data
from Phase I / II trial and long - term follow - up of GS010 in Ophthalmology, the journal of the American Academy of Ophthalmology
However, subset analyses of
phase III trials suggest that patients with EGFR mutation -
positive NSCLCs do not benefit
from immunotherapy compared with docetaxel.
Reykjavik, ICELAND, January 9, 2008 — deCODE genetics (Nasdaq: DCGN) today announced
positive topline results
from its
Phase IIa clinical trial for DG051, the company's leukotriene A4 hydrolase inhibitor being developed for the prevention of heart attack.
deCODE genetics (Nasdaq: DCGN) today announced
positive top - line results
from its
Phase I multiple dose clinical trial of DG051, which the company is developing for the prevention of heart attack.
The
positive results
from the two
phase III studies of ipilimumab were made possible in part through the evolution of the clinical science, which is based on new models of academic - industry partnership to advance immunotherapy development.
Following
positive initial results
from Phase I safety trials evaluating direct administration of VRC01, an HIV - specific antibody that is able to neutralize a broad variety of HIV strains, the National Institute of Allergy and Infectious Diseases (NIAID) is preparing for a series of further studies to see if this broadly neutralizing antibody is effective in preventing transmission of HIV
from mothers to their infants, as well as among high - risk adults.
PPMD and Action Duchenne hosted a webinar update last week on the recent report that Summit has announced
positive 24 - week interim results
from the open - label
Phase 2 proof of concept clinical trial, PhaseOut DMD.
ViaCyte reported
positive preliminary results
from the Company's
Phase 1/2 clinical trial of PEC - EnCap (also known as VC - 01) product candidate.
When the PDO is in a
positive (warm)
phase, a low - pressure center called the Aleutian Low hovers over the state and relatively warm winter winds blow into Alaska
from the southwest, according to the National Oceanic and Atmospheric Administration (NOAA).
the static or isometric
phase, during which time the weight is changing
from the negative to the
positive phase (in other words, «holding» the weight)
stay strong Charlotte, i love reading your blog and you have inspired me in many ways, not just fashion wise, im sure you will continue to inspire me throughout this
phase, but first and foremost look after yourself and keep
positive, sending love
from london, and anyway scars are sooo hot right now;) x
A
positive response
from potential consumers helped Chevy to decide upon a production schedule that has brought these two design packages out of a prototypical stage and into a production
phase, relatively quickly.
Adoption age is a balancing act between protecting puppy
from fear experiences during fear imprinting
phase, and making sure it gets heaps of
positive exposure to a wide range of people, places and things before 12 to 14 weeks of age to ensure successful socialization.
So I want to foster a
positive blog, that moves us all forward, away
from our Brandon
phase.
83 WebHubTelescope: Marler, you don't seriously believe that there is some new state of matter or new
phase transition that allows water vapor to be a
positive feedback
from 255K to 288K but then do a U-turn and become a negative feedback when the temperature hits 289K?
Marler, you don't seriously believe that there is some new state of matter or new
phase transition that allows water vapor to be a
positive feedback
from 255K to 288K but then do a U-turn and become a negative feedback when the temperature hits 289K?
Note especially Figure 2 and the related statement, «In 1976, a stepwise shift appears in the temperature data, which corresponds to a
phase shift of the Pacific Decadal Oscillation
from a negative
phase to a
positive phase.»
Adam G: You can not conclude that just
from looking at a basin which has less than 15 % of the total global tropical cyclone activity, and also selecting groups of years that coincide exactly with the
positive and negative Atlantic Multi-decadal Oscillation
phases, which would dominate over any AGW trend in this basin if it exists.
[Response: There is evidence that the enhanced continental winter warming in the Northern Hemisphere, which has resulted at least in part
from a recent trend towards the
positive phase of the Arctic Oscillation (AO), may in fact also represent a response to anthropogenic impacts on climate.
Typically, during a
positive phase of the AO, surface winds push ice away
from the shores of Siberia, and any young, thin ice that is subsequently formed is prone to melting in summer.
We are pleased to recognize the
positive impact with over $ 18 million in supplies, equipment, utilities and fuel sourced
from local businesses during the construction
phase and more than $ 20,000 contributed to local organizations to assist in their missions.»
Where things get a little mysterious is in the attribution of the warming subsurface to a change in the NA gyre circulation, which is attributed to a switch in the NAO (North Atlantic Oscillation)
from a
positive to a negative
phase.
The study, published in the journal Nature Geosciences, suggests that the change of
phase of the Interdecadal Pacific Oscillation (IPO)
from positive to negative, or vice versa, could initiate chain reaction of climate impact that may affect the sea ice formation in the Antarctic region.
You just need to add that more zonal jets when the sun is active widen the subtropical high pressure cells and allow more energy into the oceans to skew Enso in favour of El Nino over and above the basic 60 year periodicity so as to get the observed millennial climate cycling.and the temperature stepping
from one PDO
positive or negative
phase to the next.
Nor does it deal with the upward or downward stepping of temperatures
from one
positive or negative ocean
phase to the next.
The graphic below (Roemmich & Gilson [2011]- The Global Ocean Imprint of ENSO) is derived
from ARGO subsurface temperature observations for the region 60 ° N - 60 ° S, the red line denotes the
positive / negative
phases of ENSO, and the black line is the sea surface temperature anomaly.
Interactions between externally - forced climate signals
from sunspot peaks and the internally - generated Pacific Decadal and North Atlantic Oscillations «When the PDO is in
phase with the 11 year sunspot cycle there are
positive SLP anomalies in the Gulf of Alaska, nearly no anomalous zonal SLP gradient across the equatorial Pacific, and a mix of small
positive and negative SST anomalies there.
This could help explain the slowdown of the Atlantic Meridional Overturning Circulation (AMOC)
from 2006 onwards, but regardless, the slow down of the AMOC might help shift the climate system back toward the
positive IPO
phase.