Results: Target SSTR2 gene expression occurred exclusively in «proinflammatory» M1 macrophages, specific (68) Ga - DOTATATE ligand binding to SST2 receptors occurred in CD68 -
positive macrophage - rich carotid plaque regions, and carotid SSTR2 mRNA was highly correlated with in vivo (68) Ga - DOTATATE PET signals (r = 0.89; 95 % confidence interval [CI]: 0.28 to 0.99; p = 0.02).
B. Hall et al (2016) Aging of mice is associated with p16 (Ink4a)- and β - galactosidase -
positive macrophage accumulation that can be induced in young mice by senescent cells (http://www.aging-us.com/article/100991)
However, muscle from both lean and obese animals was infiltrated and surrounded by adipose tissue that contained significant numbers of F4 / 80 -
positive macrophages (a and b).
The percentage of F4 / 80 -
positive macrophages within this adipose tissue was markedly increased in obese compared with lean mice (e, P < 0.005).
Lymph node gp120 specific B cells extract locally injected HIV - 1 gp120 from SIGN - R1
positive macrophages that line the subcapsular sinus overlying the lymph node interfollicular channels.
Not exact matches
On top of their
positive effect on pathogens,
macrophages can also play a negative role in cancer biology.
Steve Gerondakis and colleagues establish that Rel (from the c - rel gene) in mice is a
positive or negative regulator of transcription in
macrophages and that Rel has distinct roles in different
macrophage populations.
The Rel subunit of NF - kappaB - like transcription factors is a
positive and negative regulator of
macrophage gene expression: distinct roles for Rel in different
macrophage populations.
Infiltrating cells in the myocardium and skeletal muscle were
positive for the T - cell marker CD3 or the
macrophage marker CD68.
Doing so lets
macrophages transfer
positive ions — and a
positive electric charge.
The large pigmented CD68 -
positive cells observed in the subretinal space at 13 weeks are likely to be
macrophages / microglia filled with melanin [46], [47] from the transplanted human iPS - RPE cells.
In Part 1 of this two part article I reviewed the
positive results of a research study for cancer treatment that combined the ketogenic diet, Bravo Yogurt, and a newly formulated
macrophage activating factor called Rerum.
It is one of the
positive acute - phase proteins that all respond in this general way when your pet's
macrophages and T - cells release pro-inflammatory cytokines.