Sentences with phrase «positive outcome of your trial»

You may also consider hiring a traffic ticket attorney to represent you in court and ensure a positive outcome of your trial.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Long - term outcome of a randomized controlled universal prevention trial through a positive parenting program: is it worth the effort?

The success of Legacy has been documented empirically in a pair of randomized controlled trials showing positive results on children's behavioral outcomes.

We found that only about one - third of the public trust medical evidence, with about two - thirds prioritising the advice of friends and family, and that about three in five British adults and four in five doctors believe that clinical trials funded by the pharmaceutical industry are often biased to produce a positive outcome.

After the positive results from a random drug test, she was pulled from her security post at Gracie Mansion and remains on paid desk duty in Queens pending the outcome of the trial.

A novel strategy to screen pregnant women for malaria with rapid diagnostic tests and treat the test - positive women with effective antimalarials does not lower the risk of adverse pregnancy outcomes compared with treating all pregnant women with the malaria preventive sulfadoxine - pyrimethamine (SP) in sub-Saharan Africa, according to an open label randomized trial published this week in PLOS Medicine by Feiko ter Kuile, of the Liverpool School of Tropical Medicine, and colleagues.

«Since several BACE1 inhibitors are currently being evaluated in clinical phase 3 trials for the treatment of Alzheimer's disease, the identification of potential side effects will be of great importance to ensure a positive clinical outcome,» said Dr. Jochen Herms, a Professor of translational brain research at Ludwig - Maximilians - University Munich.

«The recent niacin clinical trials offer important new evidence that raising «good» cholesterol (HDL) levels on top of statin therapy does not have the positive outcome that had been hoped for,» said Neil Stone, M.D., the Robert Bonow MD Professor in Cardiology at Feinberg and a cardiologist at Northwestern Memorial Hospital.

While some are suggesting the failure of these BACE1 trials indicate that the amyloid plaque hypothesis for Alzheimer's disease may in fact be wrong, other recent research still suggests more targeted methods of inhibiting the enzyme could result in positive outcomes.

If simply learning that one is biomarker positive causes a person to perform worse on cognitive testing, then primary outcomes data of AD trials may not be valid.

A meta - analysis of randomized controlled trials involving individuals with vascular disease, showed that mindfulness interventions reduced stress, depression and anxiety, as well as evidence that mindfulness has a positive impact on physical outcomes such as blood pressure and stress hormones.

We're thrilled that Magnolia's study — an independent, randomized control trial study, which is the gold standard for rigorous educational research — shows the positive and dramatic impact of our solutions on student learning outcomes.

So, there are a number of trials, albeit much smaller than this EEF trial, which suggest that a Lesson Study approach can have significant, positive impact on student outcomes, but only when the content is of high quality.

Our board of directors recognized that there was a potential for creating significant value for shareholders by continuing operations, but on balance our board of directors concluded that the risks of a negative outcome, either due to failure of our research and development efforts to yield a successful outcome, or the failure to obtain necessary financing even with positive clinical trial data, and the resulting lower liquidation value in the future, outweighed the potential value to shareholders from continuing operations.

Even had Myrexis capitalized R&D (which it didn't), the termination of drug trials (presumably because the trials were not worth pursuing as the likelihood of a positive outcome was low) would have triggered a reclassification of the capitalized expenditures to current expense, i.e. a «write down», leaving capitalized only that portion of any expenditures which had a reasonable probability of retaining value.

The majority of personal injury lawyers would only take a portion of your money (a contingency fee) if you receive a positive outcome at trial.

We have significant knowledge of antitrust and competition laws around the world and the practical trial and litigation experience required to achieve substantive and positive outcomes for our clients.

Fierce litigation is a part of our history, so we are always willing to go to trial to battle for a positive outcome.

New Haven, CT based criminal lawyer Norm Pattis, veteran of 100 + jury trials and high profile criminal defense expert for national media outlets, and the Connecticut criminal defense attorneys of The Pattis & Smith Law Firm have an extraordinary record of positive outcomes in CT felony and CT misdemeanor criminal cases including:

Britton conducted a RCT in a private independent school comparing a mindfulness meditation class with an active control (n = 101), finding that mindfulness was associated with reductions in thoughts of self - harm.35 A recent trial of a mindfulness program compared with a social responsibility control in a mostly middle - class population showed that mindfulness led to positive outcomes in psychological symptoms, cognitive control, interpersonal outcomes, and stress physiology.36 Although these findings are promising, little information is available on mindfulness instruction for low - income, urban, minority populations.

It is encouraging that the Family Links Nurturing Programme continues to be widely used throughout Wales, recognising the limitations of the trial and using other evidence of positive outcomes.

Importantly, states were required to spend at least three - quarters of the federal funds on home visiting models that met federal standards of evidence - based effectiveness.1 As many policy scholars have noted, that a national initiative brought the importance of evidence - based practice to the forefront of public policy is a triumph for social science and demonstrates the importance of rigorous program evaluation.2 With that triumph, however, comes a responsibility to ensure that the public's expectations for success of these programs are consistent with what researchers understand about the empirical evidence — will the same positive outcomes found in programs» randomized controlled trials emerge when those programs are taken to scale?

Further UK trials with long term follow up will also be needed, in particular larger trials, including all families, which use outcome measures capable of measuring change at the positive end of the mental health spectrum.

The conduct of such a trial would be greatly facilitated by the development of outcome measures which captured the full range of the components of positive mental health.

Group parenting programmes have been shown to have a positive impact on the mental health of children and parents in the short term.9 — 12 Positive results have been obtained from randomised controlled trials and other studies with parents of children with clinically defined behaviour disorders, 9,13,14 children at high risk of behaviour problems, 9,15 and to a lesser extent with normal populations.16, 17 They have also been obtained in trials of interventions for parents and children of different ages.18, 19 The number of trials carried out in the UK is small.13, 15,20,21 A recent systematic review concluded that these programmes are effective in the long term, 12 but most of the trials on which this review was based used a waiting list control design, and as a result outcome data are not reported on the control groups beyond 6positive impact on the mental health of children and parents in the short term.9 — 12 Positive results have been obtained from randomised controlled trials and other studies with parents of children with clinically defined behaviour disorders, 9,13,14 children at high risk of behaviour problems, 9,15 and to a lesser extent with normal populations.16, 17 They have also been obtained in trials of interventions for parents and children of different ages.18, 19 The number of trials carried out in the UK is small.13, 15,20,21 A recent systematic review concluded that these programmes are effective in the long term, 12 but most of the trials on which this review was based used a waiting list control design, and as a result outcome data are not reported on the control groups beyond 6Positive results have been obtained from randomised controlled trials and other studies with parents of children with clinically defined behaviour disorders, 9,13,14 children at high risk of behaviour problems, 9,15 and to a lesser extent with normal populations.16, 17 They have also been obtained in trials of interventions for parents and children of different ages.18, 19 The number of trials carried out in the UK is small.13, 15,20,21 A recent systematic review concluded that these programmes are effective in the long term, 12 but most of the trials on which this review was based used a waiting list control design, and as a result outcome data are not reported on the control groups beyond 6 months.

Though based around sovereign tribal government in Indian country, the principles of «contracting and compacting», the experience to date and the positive outcomes appear to have a quite close bearing on recent Australian developments such as the COAG «whole - of - government» trials.

Compared to control groups, babies of parents enrolled prenatally in home visiting programs had better birth outcomes, and the programs were found to have a positive impact on breastfeeding and immunization rates., In other randomized trials, participating children were found to have a reduction in language delays at 21 months, reductions in mental health problems, fewer behavior problems, and increased mental development.

A study of individual cognitive therapy for bipolar disorder showed positive outcomes at 1 - year follow - up, but the benefits were reduced over time, suggesting the need for booster sessions to sustain the gains.19 As with many forms of therapy, CBT has been found to be more successful in reducing relapse in the depressive pole compared with the manic pole.30 A large randomised trial of CBT showed no difference between CBT and treatment as usual, when all participants were included in the analyses.31 However, results of a post-hoc analysis suggested that CBT was effective for participants who reported fewer than 12 prior episodes of illness and were not acutely unwell when therapy began; numbers of episodes of mania rather than depression seemed to predict treatment response.32 Such data can help guide the clinical application of CBT for bipolar patients.

Long - term outcome of a randomized controlled universal prevention trial through a positive parenting program: Is it worth the effort?

The trial indicated positive effects on two out of five language outcomes.

Editors» Strategic Implications: In this important and well controlled trial, the authors demonstrate that university partnership - supported community teams, especially when supported with ongoing technical assistance, can continue to produce positive outcomes even after much of the control over delivery of programs is turned over to representatives of the communities in which they are implemented.