Limited evidence from studies evaluating the use of screening pelvic examination alone for ovarian cancer detection generally reported
low positive predictive values.
They found that both cancer prevalence and
positive predictive value of lung cancer screening with LDCT were higher in the 65 + cohort than in the under - 65 cohort.
The results of the study demonstrated that analyzing ctDNA from plasma is feasible for the identification of EGFR mutations with mutation status concordance in 1,162 matched samples of 89 % (sensitivity 46 %; specificity 97 %; positive predictive value [PPV] 78 %; negative PV 90 %).
«The tests are artificial and contrived,» said Dr. Gary J. Patronek, an adjunct professor at the veterinary medicine school at Tufts, who published an analysis concluding that the tests have no
more positive predictive value for aggression than a coin toss.
Researchers concluded that excess iodine intake can induce production of TPO and TG antibodies, both of which have
positive predictive value for Hashimoto's thyroiditis (3).
He found that a score of 14 is
a positive predictive value for peanuts, and thus likely to indicate a reaction.
The strongest predictors of respiratory distress were maximal volume > 24.0 cm (3) by MRI (100 % sensitivity, 91 % specificity, 60 %
positive predictive value, and 100 % negative predictive value) and maximal volume > 34.0 cm (3) by US (100 % sensitivity, 85 % specificity, 54 % positive predictive value, and 100 % negative predictive value).
One way that investigators determine whether a medical test should be used as a guide to a patient's condition is by applying a somewhat obscure statistical ratio called
a positive predictive value, or PPV.
This equates to
a positive predictive value of 40 percent for detecting invasive ovarian cancer.
The Positive Predictive Value (PPV) was 95.8 %, and the Negative Predictive Value (NPV) 99.2 %.
Of the women who get a positive result, only 135 of them really have GDM; this is
the positive predictive value and, in this case, it's 135/1180 = 11.44 %.
Testing the levels of your antibodies can give
you a Positive Predictive Value of developing an autoimmune disease.
There is a factor called PPV, or
Positive Predictive Value.
Using Ioannidis» formula for
positive predictive value, we find:
Based on a sensitivity of 45 %, a specificity of 85 % and a prevalence of 10 % (realistic estimates consistent with a non-referred population of children), only 25 % of children with externalising behaviour will have antisocial behaviour or conduct disorder (
the positive predictive value, -LCB- relative risk in a longitudinal study is 3.0, 95 % CI 1.2 to 6.3 -RCB- †).
Using the 1 - month prevalence of major depression derived from the Diagnostic Interview Schedule (DIS) as criterion, the weighted sensitivity of the CES - D was 100 %; specificity 88 %; and
positive predictive value 13 · 2 %.
When a positive response to either or both of the 2 questions was considered, the sensitivity was 74 %, the specificity was 80 %,
the positive predictive value was 36 %, and the negative predictive value was 95 %.
Key Question # 1 (accuracy of screening tools): Studies on the accuracy of screening tools will be included if they compared a screening instrument with a valid criterion standard, defined as a DSM diagnosis of MDD or an ICD diagnosis of depressive episode based on a validated diagnostic interview procedure, and if they reported data allowing determination of sensitivity and specificity,
positive predictive value, and negative predictive value.
Positive predictive value: the proportion of people who score positive on the test who actually have the disorder.
The estimates of sensitivity, specificity and
positive predictive value, being based on a large random sample, offer improved guidelines for the use of the EPDS by the primary care team.
However, in the study of Mazefsky et al. (2011), it was also found that the results of the internal reliability of the self - report questionnaire were as good, or better, than those of the standardization samples and that of all self - report measures, the RCMAS (Revised Children's Manifest Anxiety Scale; Reynolds and Richmond 1985) showed the most promise (with rather high specificity and
positive predictive values).