If Juno shows
positive results in its studies for JCAR017, the stock is poised to increase.
Not exact matches
Actual
results and the timing of events could differ materially from those anticipated
in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy
in clinical testing; Alder's ability to conduct clinical trials and
studies of eptinezumab sufficient to achieve a
positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes
in economic and business conditions; and other factors discussed under the caption «Risk Factors»
in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.
The late MIT economist Rudiger Dornbusch made an extensive
study of the
results of populist economic programmes around the world, finding that while they sometimes had immediate
positive results, over the medium - and long - term they were catastrophic for the working class
in whose name they were launched.
June 2014 — Facebook data scientists publish a
study detailing the
results of an experiment on nearly 700,000 users to determine whether showing them more
positive or negative sentiment posts
in the News Feed would affect their happiness levels (as deduced by what they posted).
That's why, when Biogen shared initial
positive results from an early
study in December, the stock jumped 6 percent — and has continued climbing, up 39 percent since Dec. 1, compared with a 19 percent gain for the Nasdaq biotechnology index.
Biotech Announces
Positive Topline Data
in Tourette Syndrome Source: Streetwise Reports (4/11/18) Francois Brisebois, a Laidlaw & Co. analyst, reviewed the recently released
study results and upcoming catalysts.
A new hormonal therapy designed to treat uterine fibroids called relugolix has finished a Phase 3
study in Japan, and the
results are
positive.
This is exactly what the
study discovered: A paper
in psychology or psychiatry is about five times as likely to report a
positive result as one
in astrophysics.
The truth
in many peer - reviewed and stoichmetrically valid research
studies show
positive and healthy outcomes as a
result of prayer.
This
study leaves open the question of whether the green tea tested
in this
study is contaminated with gluten or if something
in the green tea is causing false
positive results.
However,
results from
studies undertaken
in 2011 — 12 and 2012 — 13 provide further evidence of
positive results achieved through the active use of environmental water.
In fact, one
study found that soy protein supplements did not produce the same
positive results when compared with whey — suggesting that whey has some advantage over protein sources.
A
study found that different flavors of peanuts — salted, spicy, honey - roasted, or unsalted —
result in positive health benefits.
A recent
study from India published
in the Journal of Food Science Technology showed
positive results in improving glucose metabolism
in high fructose diets
in rats.
Though we found some rigorous
studies that after controlling for certain variables showed
positive results of the AP program, especially
in the sciences, we believe more research needs to be done before we can verify the broad claim that taking AP classes makes students more likely to succeed
in college.
While these reported interventions target the infant, other interventions target the mother - infant interaction48 or the whole family (rather just the mother) 49,50 to improve parental skills by providing practical parental care techniques (such as sleeping habits and feeding)
in combination with psychoeducation about the postpartum period and mindfulness techniques.48 This set of
studies have shown
positive results such that maternal depression, anxiety scores48 and baby crying times, 48,50 were reduced.
Although not directly comparable, our findings are
in broad agreement with those from routine data in Scotland that have indicated a positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our findings reinforce those of Coutinho and colleagues who reported that high exclusive breastfeeding rates achieved in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in broad agreement with those from routine data
in Scotland that have indicated a positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our findings reinforce those of Coutinho and colleagues who reported that high exclusive breastfeeding rates achieved in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in Scotland that have indicated a
positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our findings reinforce those of Coutinho and colleagues who reported that high exclusive breastfeeding rates achieved
in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented
in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in combination with post-natal home visits.35 Similarly
in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in Italy, training of staff with an adapted version of the Baby Friendly course content
resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in high breastfeeding rates at discharge, with a rapid decrease
in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in the days after leaving hospital.36
In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
In contrast, a cluster randomized trial
in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational
study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in Germany.38 Mothers
in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in Belarus stay
in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in hospital post-partum for 6 — 7 days, and
in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in Germany for 5 days, with post-natal support likely to be particularly important
in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in countries where mothers stay
in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based interventio
in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based intervention.
While weight gain during pregnancy is normal and necessary,
studies have shown that certain ranges of weight gain given a specific body mass index (BMI)
result in more
positive outcomes for both fetus and mother.
Some triggers for purging behavior also found
in study results includes personality shifts such as increased negative affect, or extreme changes
in negative emotions or lowered self - esteem before a purging episode followed by an increase
in positive affect following purging.
She writes, «Some
studies of children
in Asia and Africa have found a
positive relationship between prolonged breastfeeding and growth, with a decrease
in the incidence of malnutrition.4 - 6 Other research has reported a negative association between prolonged breastfeeding and growth,
resulting in lower nutritional status.7, 8»
Another
study (Artini, DiBerardino, Papini, Genazzani, Simi, Ruggiero, & Cela, 2013) offered similar
positive results on ovarian function, as well as improvement of insulin sensitivity
in women with PCOS who were taking myo - inositol (
in this
study, the dosage was only 2g per day).
The clinical trial
in humans was based on
positive results of a
study in mice published
in Nature Communications
in Sept. 2015.
In one study that pooled numerous surveys of researchers in diverse fields, a third of scientists owned up to questionable research practices like cherry - picking data that yield positive result
In one
study that pooled numerous surveys of researchers
in diverse fields, a third of scientists owned up to questionable research practices like cherry - picking data that yield positive result
in diverse fields, a third of scientists owned up to questionable research practices like cherry - picking data that yield
positive results.
«We know that urate has neuroprotective properties
in animal models, and an unusual convergence of human
studies suggested its possible use as a disease - modifying strategy
in Parkinson's; so the
positive results of this trial are very encouraging.»
According to a new
study published online today
in Science, the tiny differences found
in previous
studies may have
resulted from a slight tendency on the part of political conservatives to «self - enhance,» or view themselves
in an unrealistically
positive light.
«The counterintuitive finding that extremely difficult experiences can sometimes also be very meaningful experiences is consistent with what we see
in our
studies with psilocybin — that resolution of a difficult experience, sometimes described as catharsis, often
results in positive personal meaning or spiritual significance,» Griffiths says.
«Our review of the literature showed several
positive trial
results, but we also found important research limitations
in the
studies, indicating a need for higher quality, more definitive trials on antidepressant use for postsurgical pain.»
Results of a multi ‐ center clinical
study found a 31 percent reduction
in unnecessary biopsies due to false ‐
positives as a
result of using the phi test.1
«Such a high rate of a false
positives in this particular
study was unexpected,» says Tandy - Connor, who believes that some of the discrepancies
in the
results can be explained by technical differences between the various testing methods used.
«Future
studies are necessary to determine the incidence of
positive xenodiagnostic
results for B. burgdorferi after antibiotic treatment, if these
results represent viable organisms or remnants of infection, and whether these
results can be related to ongoing symptoms
in patients after therapy for Lyme disease,» they write.
The
results of the new
study are notable because
positive effects of an intervention, especially one that aims to improve self - regulation and academic achievement, can be difficult for researchers to find, said McClelland, the Katherine E. Smith Healthy Children and Families Professor
in the College of Public Health and Human Sciences.
If the
results of this
study are also
positive, then this will
result in a change
in practice.»
The negative - valence mechanism that AGRP neurons utilize contrasts with the majority of hunger - associated neurons previously
studied, which stimulate reward pathways and
result in positive feelings when hunger is satisfied.
When comparing testing sites that dispensed coupons with those that did not,
study results show there was no significant improvement
in the percentage of people who were successfully linked to medical care after HIV diagnosis, possibly due to the fact that there were fewer than anticipated HIV -
positive individuals identified at the HIV test sites.
Several
studies published
in PLoS Medicine this week conclude that the MTB / RIF test is very effective at diagnosing TB
in HIV -
positive patients, which is particularly difficult because they often have smear - negative
results because their TB is disseminated or extrapulmonary.
A gene that has
positive effects during puberty can be bad for us
in adulthood,» says
study leader Lukas Pezawas, describing the
results.
«Despite the
positive results shown through research, the successful transition from nondegradable plastic mulch to biodegradable plastic mulch use
in agriculture, ultimately, will be grower driven,» said Jeremy Cowan, lead author of a
study appearing
in HortTechnology.
Specifically, Delfraissy says if the monkey
studies and the finer analysis of patient samples have
positive results, perhaps the standard of care should include favipiravir as part of the control arm
in studies of ZMapp and other experimental treatments.
The
study, appearing March 9
in the journal Scientific Reports, directly tested the antibodies used
in previous analyses and showed that they cross-reacted with proteins other than irisin, yielding a false
positive result.
The drug has shown
positive results in recent
studies of mouse models of these diseases.
In their study (1), Sebastiani et al. used a number of different genotyping platforms and neglected to perform data quality - control steps, which resulted in their reporting several false - positive single - nucleotide polymorphism (SNP) association
In their
study (1), Sebastiani et al. used a number of different genotyping platforms and neglected to perform data quality - control steps, which
resulted in their reporting several false - positive single - nucleotide polymorphism (SNP) association
in their reporting several false -
positive single - nucleotide polymorphism (SNP) associations.
The short note, by Editor -
in - Chief Bruce Alberts, acknowledged that the
study's authors «used a number of different genotyping platforms and neglected to perform data - quality control steps, which
resulted in their reporting several false -
positive single - nucleotide polymorphism (SNP) associations.»
Overall,
studies in the field indicate that children from low - income families tend to show the most gains from social emotional learning interventions, but
results for other groups of students are more mixed, although a number of
studies show
positive effects.
«The
results of the
study are truly promising, since we were able to show for the first time that A2A adenosine receptor antagonists actually have very
positive effects
in an animal model simulating hallmark characteristics and progression of the disease.
Based on the
results, published today
in JAMA Internal Medicine, the
study authors recommend communications training for physicians that fosters
positive experiences for patients without agreeing to all requests for particular diagnostics or treatments.
Similarly,
in a re-analysis of
results of a previous
study, my colleague Brooke Macnamara and I found that fluid intelligence — the general ability to reason and think logically — was a strong
positive predictor of skill
in the board game GO, as measured by a laboratory task that was specially designed to measure a GO player's ability to evaluate game situations and select optimal moves.
Additional limitations to the traditional approach include: costly failures to replicate
positive results in larger trials; difficulty
in determining the reasons for negative
results; low yield
in terms of identifying disease or intervention mechanisms due to an exclusive focus on symptom change and clinical endpoints; and, the expensive and very lengthy practice of first establishing multi-component psychosocial treatments followed by years of «unpacking»
studies.
The company has seen
positive results from
studies for anti-caries and periodontal therapy that look promising
in their ability to affect plaque reduction, influencing dental hygiene and systemic medicine.
Of the 22 patients whose tumors successfully grafted, six died before data from the mice were available, but
in 13 of the remaining 16 cases, there was a positive correlation between mouse and human results.2 In a second study, performed in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutations
in 13 of the remaining 16 cases, there was a
positive correlation between mouse and human
results.2
In a second study, performed in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutations
In a second
study, performed
in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutations
in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on
results from personalized PDX mice had partial tumor remissions, even
in cases where genetic sequencing of the tumor showed no actionable mutations
in cases where genetic sequencing of the tumor showed no actionable mutations.3
But CMS agreed to fund the bulk of the $ 100 million IDEAS
study by reimbursing participants for their PET scans, and researchers hope
positive results will persuade them to cover it
in the future.