Sentences with phrase «positive tumor expression»

Not exact matches

The trial investigated the drug in two separate cohorts of patients: Cohort A, which included 170 patients with heavily pretreated metastatic triple negative breast cancer (mTNBC) regardless of PD - L1 expression, and Cohort B, which included 52 patients with PD - L1 - positive tumors who received it as first - line therapy.

When the team analyzed tissues from 261 patients with NSCLC, they found an inverse correlation between the two molecules; that is, more than 80 percent of patient tissues with low levels of the tumor suppressing C / EBPα were positive for BMI1 expression.

The authors looked at gene expression in a panel of 50 ERBB2 (Her2) positive breast tumors and found that this pattern held up: DNA hypomethylation is associated with decreased gene expression in breast cancer.

A, HIF - 1α and Glut1 expression in ER - α — positive (i) and negative (ii) xenografts compared with tumor size (mm3).