Sentences with phrase «positive tumors in mice»

The conjugate, which they named «chemocoxib A,» reduced growth of COX - 2 positive tumors in mice by 50 percent, but didn't have any effect on tumors that didn't express the enzyme.

Not exact matches

Shah next plans to rationally combine the toxin - secreting stem cells with a number of different therapeutic stem cells developed by his team to further enhance their positive results in mouse models of glioblastoma, the most common brain tumor in human adults.

The new technology was tested in mice for the ability to generate antibodies in their blood stream that would target human PSMA as well as target PSMA - positive tumors.

Of the 22 patients whose tumors successfully grafted, six died before data from the mice were available, but in 13 of the remaining 16 cases, there was a positive correlation between mouse and human results.2 In a second study, performed in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutationsin 13 of the remaining 16 cases, there was a positive correlation between mouse and human results.2 In a second study, performed in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutationsIn a second study, performed in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutationsin collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutationsin cases where genetic sequencing of the tumor showed no actionable mutations.3

E, in vivo tumor formation for ER - positive (MCF7) and negative (468) cells following 21 % or 1 % pretreatment (numbers represent mice in group).

In the study, researchers removed the ovaries of female mice to mimic the effects of post-menopausal women before implanting estrogen - receptor positive cancer tumors into the test subjects.

After embedding ER positive / PR positive breast tumors in a number of mice, they exposed some of the mice to estrogen only, others to both estrogen and progesterone, and others to no hormones at all.