Although the antibody approach has been successful, it increases the risk
of severe allergic
reactions as well as the
possibility that the patient's
immune system will become sensitized, destroying the antibodies and making long - term treatment less effective.
Possibilities include environmental toxins linked to crops or to plant decay by - products (e.g., bacterial / fungal toxins), as well as a combination
of the former with agricultural practices, atmospheric chemistry, and an idiosyncratic
immune reaction in genetically susceptible children (28, 29).