The researchers performed a «genome - wide» study in children with newly diagnosed CD, before any treatment, to look for
possible epigenetic changes that may affect gene behavior.
Not exact matches
As a cancer researcher, do you think the mechanisms of tumor growth are somehow
changing to come into line with your perceptions, or is it
possible that the process of our learning more about DNA mutations and cell architecture and nutrient exchange and
epigenetic effects make it
possible for us to inch ever closer to understanding that which is already going on under our noses?
In the future, it may be
possible to screen sperm during IVF or block unwanted
epigenetic changes with drug therapy, says Teague.
What is more, she even thinks it
possible that the
epigenetic changes were somehow triggered by the cave environment in the first place.
It might be
possible then to link the alterations to environmental
changes such as stressful events or diet, which have been shown to cause inheritable
epigenetic changes in mice.
Although there is evidence from mice that these
changes can be inherited, classical genetics says this shouldn't be
possible because
epigenetic marks on sperm and eggs are wiped clean after fertilisation.
With additional research and knowledge, she said, it may also be
possible one day to use these
epigenetic changes as markers, which can tell that a child is at risk of obesity and other diseases.
And because
epigenetic changes typically occur early in life, it may one day be
possible to identify young people at risk for suicide by studying their methylation patterns and then to treat them with drugs that regulate this mechanism, Szyf notes.
Is it
possible that we can see
epigenetic changes in the human brain because of exposure to environmental toxins?
In agreement with the hypothesis that such adaptations are due to
epigenetic changes occurring during preimplantation, we have detected
epigenetic labile genes in the mouse embryo genomes that allow us to study the best IVC method to produce competent and healthy embryos to ensure that assisted reproductive technologies are utilized in the most efficient and safest
possible manner.
The thing that was surprising to the scientists was the size of the effect — children differ in how fat they are, but measurement of the
epigenetic change at birth made it
possible for the scientists to predict 25 % of this variation.