«These results are powerful in that early diagnosis of mental
illness could
possibly happen with a simple blood test,
leading to better interventions, therapy and treatment options.»
This could, in very rare cases,
possibly lead to side effects, such as extreme tiredness (after a treatment), a general feeling of
illness.»
Specifically, the ACE Study model relies strongly on the idea that adverse childhood experiences create a burden of psychological stress that changes behavior, cognitions, emotions, and physical functions in ways that promote subsequent health problems and
illness.22 Among the hypothesized pathways, adverse childhood experiences
lead to depression and posttraumatic stress disorder, which in turn can
lead to substance abuse, sleep disorders, inactivity, immunosuppression, inflammatory responses, and inconsistent health care use,
possibly leading to other medical conditions later in life.23, 24 Therefore, childhood behavioral and emotional symptoms very likely represent a crucial mediator linking adverse childhood experiences and the longer term health - related problems found in the ACE substudies.