Sentences with phrase «postmortem brains of patients»
A recent human study also indicated a genetic association of the αCaMKII gene with bipolar disorder, and decreased expression of αCaMKII has been observed in postmortem brains of patients with bipolar disorder.
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More than a hundred years ago, German physician Alois Alzheimer did a grim postmortem analysis of the dementia - ravaged brain of one of his patients.
Postmortem studies of the brains of Alzheimer's patients show a dramatic destruction of neurons, and particularly neurons which secrete or utilise the neurotransmitter acetylcholine.
Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.
Several postmortem studies report the presence of inflammatory markers in the brains of depressed or mood - disordered patients.
Observations of reactive microglia in postmortem brain samples of PD patients had led to suggestions that microglia are involved in the neuropathological changes in DA neurons that are inherent to this disease.»