Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of
human material, such as
postmortem brains, primary
cell systems, and neural
cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem
cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.